Ultrasonic topic: "Ultrasonic Processing in the Pharma Industry"
Power ultrasonics is a highly efficient and reliable tool for the production of vaccines, nano-formulated drugs and drug carriers (e.g. liposomes). Hielscher Ultrasonics’ lab, pilot and industrial systems produce pharma-grade micron- and nano-emulsions / -dispersions, liposomes as well as vaccines. Hielscher’s ultrasonic systems are equipped with CIP (clean-in-place) and SIP (sterilize-in-place) and guarantee thereby safe and efficient production according to pharmaceutical standards. All specific ultrasonic processes can be easily tested in lab or bench-top scale and then be linearly scaled up to industrial production.
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Coronavirus (COVID-19, SARS-CoV-2) and Ultrasonics
Ultrasonication is a powerful tool used in biology, molecular chemistry and biochemistry as well as in the production of pharmaceuticals. Bio-sciences use ultrasonic homogenizers to lyse cells and extract proteins and other intracellular materials, the pharma industry applied ultrasonics to…
https://www.hielscher.com/coronavirus-covid-19-sars-cov-2-and-ultrasonics.htmPharmaceuticals Encapsulated in Lipid Nanoparticles with Ultrasonics
Nano-size drug carriers are widely used to deliver pharmaceutically active compounds into the targeted cells. In order to encapsulate the active substances into a drug carrier with a high bioavailability, solid lipid nanoparticles are used. Ultrasonic nano-emulsification and encapsulation is…
https://www.hielscher.com/pharmaceuticals-encapsulated-in-lipid-nanoparticles-with-ultrasonics.htmUltrasonics in Virus Research
Ultrasonic lysis and extraction is a reliable and long-time established method for the disruption of cells and the subsequent release of viruses, viral proteins, DNA, and RNA. Ultrasonics in Coronavirus Research The extraction of viruses from organ tissue is an…
https://www.hielscher.com/ultrasonics-virus-research.htmClear Nano-Emulsions with Stuph and Ultrasonics
Clear nano-emulsions have a wide range of applications in food, beverage and cosmetic formulations. Stuph Corp supplies is various food-grade, high-quality emulsifiers for the preparation of clear nano-emulsions for the use in food, drinks, tinctures, concentrates as well as skin…
https://www.hielscher.com/clear-nano-emulsions-with-stuph-and-ultrasonics.htmUltrasonic Deacetylation of Chitin to Chitosan
Chitosan is a chitin-derived biopolymer which has many applications in pharma, food, agriculture and industry. Ultrasonic deacetylation of chitin to chitosan intensifies the treatment significantly - leading to an efficient and fast process with a high chitosan yield of superior…
https://www.hielscher.com/ultrasonic-deacetylation-of-chitin-to-chitosan.htmUltrasonically Polyhydroxylated C60 (Fullerenol)
Water-soluble polyhydroxylated C60 fullerene, called fullerenol or fullerol, is a strong free radical scavenger and is therefore used as an antioxidant in supplements and pharmaceuticals. Ultrasonic hydroxylation is a rapid and simple one-step reaction, which is used to produce water-soluble…
https://www.hielscher.com/ultrasonic-polyhydroxylated-c60-fullerenol.htmUltrasonic Collagen Extraction from Jellyfish
Jellyfish collagen is a high-quality collagen, which is unique but exhibits similar properties to type I, II, III and type V collagen. Ultrasonic extraction is a purely mechanical technique, that increases yield, accelerates the process and produces high molecular weight…
https://www.hielscher.com/ultrasonic-collagen-extraction-from-jellyfish.htmW.Last – High Quality Extracts with Sonication
W.Last is an experienced company based in South Africa, which specializes in the production of premium extracts and tinctures from botanicals. W.Last uses ultrasonic extraction to manufacture their high-quality extracts, which are used for medicinal purpose, food flavouring and in…
https://www.hielscher.com/w-last-high-quality-extracts-with-sonication.htmUltrasonic Extraction of Quillaja Saponins
Saponin extracts of the Quillaja saponaria Molina tree are the main source of saponins for industrial applications. Ultrasonic extraction of Quillaja saponins yields in high quality saponins. Ultrasonic extraction is a highly efficient method to produce high yields of Quillaja…
https://www.hielscher.com/ultrasonic-extraction-of-quillaja-saponins.htmUltrasonic Capsaicin Extraction from Hot Chili Peppers
Capsaicin is the main flavour and spice compound in hot peppers, also known as chilies. To produce high-quality capsaicin as aromatic flavour and medicinal ingredient, an efficient, yet mild extraction technique is required to prevent degradation. Ultrasonic extraction is a…
https://www.hielscher.com/ultrasonic-capsaicin-extraction-from-hot-chili-peppers.htmUltrasonic Quercetin Extraction
Quercetin is a plant compound of the group of polyphenols, which is known for manifold health beenfits. In order to produce high-quality quercetin for food additives and supplements, an efficient, yet mild extraction technique is required to prevent decomposition. Ultrasonic…
https://www.hielscher.com/ultrasonic-quercetin-extraction.htmUltrasonic Anthocyanin Extraction
Anthocyanins are widely used as natural colorant and nutritional additive in food products. Ultrasonic extraction is a highly efficient and simple technique to obtain high-quality anthocyanins. The use of probe-type sonicators promotes the release of high-quality anthocyanins from plants resulting…
https://www.hielscher.com/ultrasonic-anthocyanin-extraction.htm










