UP50H – Compact Lab Homogenizer

The ultrasonic processor UP50H is typically used for the sonication of small lab samples. This homogenizer allows for the handheld or stand-mounted emulsification, dispersing, dissolving or cell disruption.

The UP100H is a compact yet powerful ultrasonic device for handheld and stand-mounted operation.The ultrasonic processor UP50H (50 watts, 30kHz) is the smallest model of our aesthetic laboratory devices, that are only supplied by Hielscher Ultrasonics in that compact form. The UP50H is used in particular in medical, biological or chemical laboratories, where small volumes need to be sonicated. Application fields are found mainly in the analytical field with applications such as the disruption of tissues, the cracking of bacteria or the homogenizing of samples in the food industry.
This device is perfectly suited for handheld operation with its lightweight 1.1kg, but it can also be operated at a stand. Generator and the transducer are combined in one unit, so there is only one cable. One power supply cord – that’s all. For volume samples from 10µL up to 250mL we offer various replaceable sonotrodes with diameters from 0.5 to 7mm. Further accessories such as flow cells made of stainless steel or glass or a timer are part of our standard program. Click at the links below, to read more about the applications of our ultrasonic devices.

The UP50H can be used in combination with a flow cell D7K for the sonication of material in continuous flow, e.g. at 10 to 50mL/min. By this, you can simulate continuous sonication processes in smallest scale. For samples larger than 250mL we recommend using the UP100H (100 watts), UP200Ht (200 watts) or the UP400St (400 watts).

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  • UP50H ultrasonic lab homogenizer for handheld and/or standmounted operation

    for handheld operation or for stand use, 50 watts, ultrasonic frequency 30kHz, automatic frequency tuning system, amplitude adjustable from 20 to 100%, pulse adjustable from 0 to 100%, dry running protected, with 9-pin DSUB interface, in portable case, with stand holder for use with stand ST1-16 or sound protection box SB2-16, with mounting tools, IP30 grade, titanium horn with female thread M6x0.75
    dimensions (LxWxH): 185x130x85mm, weight: 1.1kg



  • made of titanium, tip diameter 1mm, approx. length 80mm, male thread M6x0.75, for samples from 0.1ml up to 5ml



  • made of titanium, tip diameter 2mm, approx. length 80mm, male thread M6x0.75, for samples from 2ml up to 50ml



  • made of titanium, tip diameter 3mm, approx. length 80mm, male thread M6x0.75, for samples from 5ml up to 100ml



  • made of titanium, tip diameter 7mm, approx. length 80mm, male thread M6x0.75, for samples from 10ml up to 250ml



  • made of titanium, tip diameter 7mm, approx. length 80mm, male thread M6x0.75, with seal for closed systems



  • made of titanium, tip diameter 7mm, approx. length 160mm, male thread M6x0.75, with seal for closed systems



  • Stand for lab sample sonication

    diameter 16mm, made of stainless steel, base length 300mm, width 150mm, height 500mm



  • Clamp for lab sample sonication

    clamp for holding diam. 0 to 63mm, made of aluminum, for use with stand stands of up to 16.5mm, e.g. ST1-16



  • LabLift, e.g. for the intense sonication of liquids in glass beakers in the laboratory.

    for the easy positioning of samples under the ultrasonic probes to control immersion depth, stainless steel, footprint 100x100mm, adjustable height: 50 to 125mm



  • Timer to predefine sample sonication time

    from 00:00 to 99:59 (min:sec)



  • made of stainless steel, with cooling, hose connectors, for fluids, autoclavable, for operation with sonotrode MS7D, volume approx. 13ml, with stand-adapter for stand ST1-16 (diameter 16mm)



  • made of glass, with cooling, hose connectors, for fluids, autoclavable, for operation with sonotrode MS7D (or with sonotrode MS7L2D in combination with flask adapter NSA1), volume approx. 80ml, with clamp for installation at stand, e.g. stand ST1-16 (diameter 16mm)



  • for standard flask-neck, vertically adjustable, suitable for sonotrode MS7L2D in combination with flow cell GD7K



  • Sound Protection Box SB2-16

    sound protection box, acryl glass, with divisible rod Ø16mm, vertically adjustable table, anti-slip mat, dimensions (LxWxH): 29x20x35cm, weight: 13kg, sound insulation: 22dB (A) open air measurement



  • Power Meter

    versatile, for display of current power, cumulated energy and cumulated operation time, 115V~1P, 50-60Hz



  • Power Meter

    versatile, for display of current power, cumulated energy and cumulated operation time, 230V~1P, 50-60Hz


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This video of the UP100H ultrasonic homogenizer shows its compact design and versatile applicatioos, such as dispersing, homogenizing, mixing, degassing or emulsification.

Ultrasonicator UP100H (100 Watts) - Compact Ultrasonic Homogenizer

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The ultrasonic device UP50H is a uniquely compact and powerful device for lab applications, such as homogenizing, dispersing, emulsifying and deagglomerating.
UP50H with MS7

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The compact and powerful ultrasonic disintegrator UP50H can be used at a stand or in handheld operation.

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The Ultrasonic Processor UP50H in Research and Science

The UP50H is a popular 50 watts powerful ultrasonic lab homogenizer, frequently used in research laboratories and R&D facilities. Below you can find the FactSheet of the UP50H as well as a selection of scientific articles featuring the probe-type sonicator UP50H. The articles span from cell disruption and lysis, emulsification, to the extraction of bioactive compounds from botanicals. If you are looking for a specific application and related scientific references, please contact us.

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