Ultrasonic Laboratory Devices
Typical applications of ultrasonic homogenizers include sample preparation, disintegrating and cell lysis, homogenizing, dispersing and disaggregation, particle size reduction and the acceleration of chemical reactions (sonochemistry). Hielscher offers a wide range of ultrasonic homogenizers to be used for these applications in a wide range of volumes from approx. 50µL to 2000mL. The selection of the ultrasonic processor depends on the sample volume to be sonicated. The table below, lists all laboratory devices and the recommended volume respectively.
|Device||Power [W]||Freq. [kHz]||Type||Volume [mL]|
|VialTweeter at UP200St||200||26||stand-alone||0.5||–||1.5|
|UP50H||50||30||handheld or standmounted||0.01||–||250|
|UP100H||100||30||handheld or standmounted||0.01||–||500|
|UP200Ht||200||26||handheld or standmounted||0.1||–||1000|
|UP200St_TD with SonoStep||200||26||stand-alone||30||–||500|
|Ultrasonic CupHorn||200||26||CupHorn, sonoreactor||10||–||200|
|UIS250L||250||24||laboratory sieving system|
|GDmini2||200||26||contamination-free flow cell|
Designed for the Lab
Hielscher ultrasonic laboratory devices are designed for the lab. They are very simple to setup. The handheld and standmounted devices combine generator (power supply) and transducer (converter) in a single housing. This saves desktop space and weight. Hielscher is the only manufacturer of handheld ultrasonic processors. The only plug to be connected is the main power plug, that fits into standard 115V~ or 230V~ outlets. The operation of the ultrasonic homogenizers is very simple. The devices are tuned to the optimal resonant frequency automatically, so there is no need for manual adjustments. The ultrasonic amplitude is adjustable from 20 through 100%. Alternatively to the continuous operation a cycle of intense sonication bursts can be a adjusted, e.g. for the sonication of heat-sensitive tissue.
Accuracy for Reproducible Results
For the preparation of samples as well as for the development of new applications, it is important to have a good control over all sonication parameters in order to obtain reproducible results. Hielscher ultrasonic devices allow you to control the amplitude of sonication. This is the most important sonication parameter. The mechanical amplitude is monitored constantly in the device to eliminate any deviation from the adjusted value. This makes the amplitude independent of other factors, such as immersion depth, liquid temperature or viscosity. Therefore, you can repeat each sonication by selecting the same amplitude again.
Hielscher ultrasonic laboratory devices can run continuously – 24hrs/7days, if needed. By using the laboratory devices in combination with flow cell reactors, you can process larger sample volumes. In this case, the liquid is pumped into the reactor made of glass or stainless steel. For example, a UP400St can process approx. 10 to 50 liters per hour. There it is exposed to defined intense sonication before it reaches the exit of the reactor cell. In order to cool heat-sensitive material during sonication, the flow cells are jacketed to improve heat dissipation.
When applied to liquids, ultrasound causes cavitation. The cavitational noise is in the human audible range. Sound protection boxes are available for the ultrasonic laboratory devices to reduce the noise emission to more convenient levels. This is recommended for typical laboratory environments. The sound protection boxes include a stand pole and an adjustable table (acrylic glass) to hold the sample. Click here to read more about ultrasonic noise emission!