Ultrasonic topic: "Ultrasonic Processing in the Pharma Industry"
Power ultrasonics is a highly efficient and reliable tool for the production of vaccines, nano-formulated drugs and drug carriers (e.g. liposomes). Hielscher Ultrasonics’ lab, pilot and industrial systems produce pharma-grade micron- and nano-emulsions / -dispersions, liposomes as well as vaccines. Hielscher’s ultrasonic systems are equipped with CIP (clean-in-place) and SIP (sterilize-in-place) and guarantee thereby safe and efficient production according to pharmaceutical standards. All specific ultrasonic processes can be easily tested in lab or bench-top scale and then be linearly scaled up to industrial production.
Found 63 hits. Showing results 13 - 24.
Ultrasonic Nanostructuring of Antibiotics
Ultrasonically-assisted production of antibiotics can increase their effectiveness, even against drug-resistant bacteria: The increasing number of antibiotic-resistant bacteria strains is a still unsolved problem making bacterial infections, which have been successfully treated with antibiotics within the last decades, a worldwide…
https://www.hielscher.com/ultrasonic-nanostructuring-of-antibiotics.htm
Application of Power Ultrasound using Ultrasonic Horns
Ultrasonic horns or probes are used widely for manifold liquid processing applications including homogenization, dispersing, wet-milling, emulsification, extraction, disintegration, dissolving, and de-aeration. Learn the basics about ultrasonic horns, ultrasonic probes and their applications. Ultrasonic Horn vs Ultrasonic Probe Often, the…
https://www.hielscher.com/application-of-power-ultrasound-using-ultrasonic-horns.htm
Ultrasonic Elderberry Extraction
Elderberry extracts are well-known for their antiviral properties and thereby heavily used as natural remedy to relieve flu symptoms such as fever, cough, and sore throat. To produce elderberry extracts with a high polyphenol and antioxidant content, a mild yet…
https://www.hielscher.com/ultrasonic-elderberry-extraction.htm
Nootropics and Smart Drugs Formulations with Ultrasonics
Smart drugs and nootropic supplements are consumed as “cognitive enhancers” in order to increase cognitive function, brain capacity, concentration, memory and creativity, to boost motivation and mental energy as well as to support brain health. To promote the transport of…
https://www.hielscher.com/nootropics-and-smart-drug-formulations-with-ultrasonics.htm
Water-Soluble Nano-THC Formulations With Sonication
The formulation of THC-enhanced beverages is challenging. - THC-infused drinks must be nano-emulsified in order to provide a high bioavailability and thereby potency, long-term stability and clear appearance. Ultrasonic nano-emulsification of THC into beverage is highly efficient and efficacious resulting…
https://www.hielscher.com/water-soluble-nano-thc-formulations-with-sonication.htm
Production of Hand Sanitizers with Industrial Ultrasonic Mixers
To produce hand sanitizers and disinfecting solutions, a powerful mixing technology is required to obtain a consistent mixture. Ultrasonic mixers and agitators are the most reliable and efficient mixing technology for blending and emulsifying two or more phases in order…
https://www.hielscher.com/production-of-hand-sanitizers-with-industrial-ultrasonic-mixers.htm
Ultrasonic Formulation of Nanostructured Lipid Drug Carriers
Nanostructured lipid carriers (NLCs) are an advanced form of nano-sized drug delivery systems featuring a lipid core and a water-soluble shell. NLCs have a high stability, protect the active bio-molecules against degradation and offer sustained drug release. Ultrasonication is a…
https://www.hielscher.com/ultrasonic-formulation-of-nanostructured-lipid-drug-carriers.htm
Ultrasonic Nanoliposomes for Stabilised Allicin Formulations
Allicin is a bioactive compound, which can be extracted from fresh garlic cloves. Allicin is prone to degradation and must be therefore formulated into a stabilised supplement form in order to obtain a long-term potent formula. Ultrasonic encapsulation of allicin…
https://www.hielscher.com/ultrasonic-nanoliposomes-for-stabilised-allicin-formulations.htm
Ultrasonic Production of Liposomal Omega-3 Fatty Acids
Nanoliposomes are highly effective drug carriers used to enhance the bioavailability of bioactive compounds such as omega-2 fatty acids, vitamins, and other substances. Ultrasonic encapsulation of bioactive compounds is a fast and simple technique to prepare nanoliposomes with high drug…
https://www.hielscher.com/ultrasonic-production-of-liposomal-omega-3-fatty-acids.htm
Improved Remdesivir Solubility by Sonication
Remdesivir (GS-5734) is an anti-viral drug, which is under research for treating the Ebola virus disease and COVID-19, which is caused by the Sars-CoV-2 coronavirus. Remdesivir is pharmaceutical solution, which is administered intravenously. Whilst short ultrasonic dissolving alone enhances the…
https://www.hielscher.com/improved-remdesivir-solubility-by-sonication.htm
Ultrasonic Formulation of Niosomes
Niosomes are nano-sized vesicles, which can be used as carrier for drugs (e.g. cancer drugs) and other bioactive substances. Ultrasonic emulsification is a simple and rapid method to formulate small niosomes with a high drug load. Niosome Vesicles as Nano-Carrier…
https://www.hielscher.com/ultrasonic-formulation-of-niosomes.htm
Nano-Encapsulated Intranasal Vaccine Against S. Pneumoniae with Ultrasonics
Nanoparticle-based drug carriers are an evolving technology, which allows to formulate vaccine delivery systems with a high protection rate against various diseases. Ultrasonic emulsification and encapsulation is a highly efficient method to prepare loaded nano-structured drug carriers such as nanoparticles,…
https://www.hielscher.com/nano-encapsulated-intranasal-vaccine-against-s-pneumoniae-with-ultrasonics.htm