Utrasonic topic: "Ultrasonic Processing in the Pharma Industry"
Power ultrasonics is a highly efficient and reliable tool for the production of vaccines, nano-formulated drugs and drug carriers (e.g. liposomes). Hielscher Ultrasonics’ lab, pilot and industrial systems produce pharma-grade micron- and nano-emulsions / -dispersions, liposomes as well as vaccines. Hielscher’s ultrasonic systems are equipped with CIP (clean-in-place) and SIP (sterilize-in-place) and guarantee thereby safe and efficient production according to pharmaceutical standards. All specific ultrasonic processes can be easily tested in lab or bench-top scale and then be linearly scaled up to industrial production.
12 pages about this topic are being shown:
Artemisinin can be efficiently extracted using high-performance sonication. Ultrasonic extraction gives very high yields of artemisinin using mild solvents. The process of extraction applying ultrasound is accelerated drastically. The processing conditions in ultrasonic extractors are precisely controllable, which allows…https://www.hielscher.com/highly-efficient-artemisinin-extraction-with-sonication.htm
Deep eutectic solvents (DESs) and natural deep eutectic solvents (NADES) offer advantages as extraction solvents on many levels and are thereby a promising alternative to conventional organic solvents. Deep eutectic solvent work excellent in combination with ultrasonic extraction and…https://www.hielscher.com/extraction-with-deep-eutectic-solvents.htm
Ultrasonic extraction alone or in combination with alternative extraction methods such as solvent extraction or supercritical CO2 extractors is successfully used to extract the full spectrum of cannabinoids from the cannabis plant (hemp and marijuana). In marijuana, the main…https://www.hielscher.com/supercritical-fluid-extraction-improved-by-power-ultrasonics.htm
Ultrasonically-assisted production of antibiotics can increase their effectiveness, eben against drug-resistant bacteria: The increasing number of antibiotic-resistant bacteria strains is a still unsolved problem making bacterial infections, which have been successfully treated with antibiotics within the last decades, a…https://www.hielscher.com/ultrasonic-nanostructuring-of-antibiotics.htm
Ultrasonic horns or probes are used widely for manifold liquid processing applications including homogenization, dispersing, wet-milling, emulsification, extraction, disintegration, dissolving, and de-aeration. Learn the basics about ultrasonic horns, ultrasonic probes and their applications. Ultrasonic Horn vs Ultrasonic Probe Often,…https://www.hielscher.com/application-of-power-ultrasound-using-ultrasonic-horns.htm
Elderberry extracts are well-known for their antiviral properties and thereby heavily used as natural remedy to relieve flu symptoms such as fever, cough, and sore throat. To produce elderberry extracts with a high polyphenol and antioxidant content, a mild…https://www.hielscher.com/ultrasonic-elderberry-extraction.htm
Smart drugs and nootropic supplements are consumed as “cognitive enhancers” in order to increase cognitive function, brain capacity, concentration, memory and creativity, to boost motivation and mental energy as well as to support brain health. To promote the transport…https://www.hielscher.com/nootropics-and-smart-drug-formulations-with-ultrasonics.htm
Ultrasonication is well known to be highly efficient in the preparation of liposomal formulations. Typical liposome formulations encapsulate vitamin C, CBD, curcumin, quercitin, astaxanthin, peptides and manifiold other bioactive compounds using ultrasonication. Ultrasonic liposome encapsulation is a simple, fast…https://www.hielscher.com/liposomal-encapsulated-bioactive-molecules-with-ultrasonics.htm
The formulation of THC-enhanced beverages is challenging. - THC-infused drinks must be nano-emulsified in order to provide a high bioavailability and thereby potency, long-term stability and clear appearance. Ultrasonic nano-emulsification of THC into beverage is highly efficient and efficacious…https://www.hielscher.com/water-soluble-nano-thc-formulations-with-sonication.htm
To produce hand sanitizers and disinfecting solutions, a powerful mixing technology is required to obtain a consistent mixture. Ultrasonic mixers and agitators are the most reliable and efficient mixing technology for blending and emulsifying two or more phases in…https://www.hielscher.com/production-of-hand-sanitizers-with-industrial-ultrasonic-mixers.htm
Famotidine is a common pharmaceutical molecule used in heartburn medications. In order to overcome the poor solubility and the resulting poor bioavailability, famotidine can be formulated into solid-lipid nanoparticles using sonication as encapsulation technique. Ultrasonically Famotidine-Loaded Solid Lipid Nanoparticles…https://www.hielscher.com/ultrasonically-formulated-famotidine-solid-lipid-nanoparticles.htm
Nanostructure lipid carriers (NLCs) are an advanced form of nano-sized drug delivery systems featuring a lipid core and a water-soluble shell. NLCs have a high stability, protect the active bio-molecules against degradation and offer sustained drug release. Ultrasonication is…https://www.hielscher.com/ultrasonic-formulation-of-nanostructured-lipid-drug-carriers.htm