Ultrasound-Assisted Extraction

Ultrasound-assisted extraction is a very efficient and easy-to-use method for the extraction of bioactive compounds from botanicals. This extraction technique is known for its efficiency, and the ability to preserve the integrity of bioactive compounds during extraction. Ultrasound-assisted extraction leverages the mechanical energy of ultrasonic waves to facilitate the extraction of valuable components from plant matrixes, a process that is not only rapid but also produces better yields compared to traditional extraction methods.

The Essence of Ultrasound-Assisted Extraction

Ultrasound-assisted extraction is a non-thermal extraction method, that preserves heat-sensitive compounds. It utilizes the mechanical energy of ultrasonic waves to generate cavitation bubbles in a slurry or paste of botanical material. The implosions of these microbubbles generate intense local high pressure and strong shear forces, which disrupt cell walls and enhance the mass transfer of solutes into the solvent. This mechanism allows for the efficient extraction of bioactive compounds, including antioxidants, essential oils, phenolic compounds, and flavonoids, under milder conditions and in significantly less time than conventional methods.

Hielscher Ultrasonic Devices: Enhancing Extraction Efficiency

Hielscher Ultrasonics specializes in the development and manufacturing of high-performance ultrasonic systems for many applications, including ultrasound-assisted extraction. Hielscher Ultrasonics is the leader in the development of high-performance, high-power ultrasonic systems. Hielscher sonicators are crucial for ensuring the consistency and quality of the extracted compounds, making Hielscher a reliable choice for both research and commercial purposes. Hielscher ultrasonic devices are designed to deliver precise control over the ultrasonic parameters, enabling the optimization of extraction processes for maximum yield and quality. The use of Hielscher ultrasonic processors and flow cells in ultrasound-assisted extraction is characterized by its versatility, scaling from laboratory to industrial extraction applications with ease.

Comparison of extraction efficiency

Comparison of Extraction Efficiency

Hielscher sonicator for the ultrasound-assisted extraction of bioactive compounds

Ultrasound-assisted extraction (agitated batch)

Botanical Extraction: A Prime Application of Ultrasound-Assisted Extraction

One of the primary advantages of ultrasound-assisted extraction is its versatility. The application of Hielscher sonicators has been particularly beneficial in the field of botanical extraction, where it is used to extract essential oils, flavonoids, phenolic compounds, and other bioactive substances from plant materials. The efficiency of Hielscher ultrasonic processors ensures a higher yield of extract with enhanced quality, compared to conventional extraction methods. Ultrasound-assisted extraction requires lower temperatures and shorter extraction times, which not only reduce energy consumption but also minimize the solvent waste generated during the process. Furthermore, the ability of this extraction method to operate effectively with a variety of solvents, including water and ethanol, which are safer for both human consumption and the environment, underscores its position as an eco-friendly extraction technique.

In this presentation we introduce you to the manufacturing of botanical extracts. We explain the challenges of producing high-quality botanical extracts and how a sonicator can help you to overcome these challenges. This presentation will show you how ultrasonic extraction works. You will learn, what benefits you can expect using a sonicator for extraction and how you can implement an ultrasonic extractor into your extract production.

Ultrasonic Botanical Extraction - How to use sonicators to extract botanical compounds

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Typical Botanicals Extracted by Ultrasound-Assisted Extraction

Below, you will find a list of common botanicals that are extracted using Hielscher sonicators. Please click on the links for more detailed information!

Operational Excellence with Hielscher Technology

Hielscher ultrasonic systems stand out for their robustness, scalability, and ease of use, making them indispensable tools in both research and industrial settings. Hielscher flow cell reactors, in particular, are engineered to facilitate continuous processing, thereby enhancing the throughput and efficiency of ultrasound-assisted extraction processes.

We would like to discuss your extraction requirements

Ultrasound-assisted extraction represents a significant advancement in the field of extraction technology. Its ability to efficiently extract bioactive compounds, coupled with the adaptability to various botanicals and scalability for industrial applications, positions Hielscher ultrasonic extractors as a key player in natural product extraction.
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Combination: Ultrasound-Assisted and Enzymatic Extraction

The combination of ultrasound-assisted extraction with enzymatic techniques can utilize the strengths of both methods. It is particularly beneficial in extracting valuable compounds from complex plant matrixes. This synergy stems the capacity to disrupt cell walls via cavitation, enhancing the substrate accessibility for enzymes, which in turn, facilitates the breakdown of complex molecules like cellulose and pectin.
An integrated approach significantly can enhance extraction efficiency and yields significantly, as the ultrasound pre-treatment markedly improves the penetration of enzymes, thereby accelerating the extraction process. Such a combination is gentle, preserving the bioactive compounds due to the mild conditions favored by enzymatic reactions, which avoid the degradation of thermally sensitive molecules.
Moreover, this synergistic method is economically advantageous. The increased extraction efficiency and yields brought about by combining ultrasound-assisted extraction with enzymatic extraction can lead to substantial reductions in production costs.



Frequently Asked Questions about Ultrasound-Assisted Extraction

How long does ultrasound assisted extraction take?

Typically, ultrasound-assisted extraction can significantly reduce extraction time, often completing processes in seconds to several minutes, a stark contrast to traditional methods that may take several hours to days.

What is an ultrasound extraction machine?

An ultrasound extraction machine is a device that uses ultrasonic energy to facilitate the extraction of compounds from various matrixes. It operates by emitting high-frequency sound waves that generate cavitation in the extraction solvent.

How does ultrasound affect extraction?

Ultrasound enhances extraction by generating cavitation, which leads to cell wall disruption, improved mass transfer, and increased solvent penetration into the plant matrix.

What are the benefits of ultrasound-assisted extraction?

The benefits include increased extraction efficiency, reduced solvent usage, lower energy consumption, and shorter extraction times, aligning with principles of green chemistry.

What are the pros and cons of ultrasound?

Pros include its non-thermal nature, scalability, and versatility across various applications. While potential drawbacks of adopting ultrasound-assisted extraction technology might include the upfront investment in equipment, these initial costs are rapidly counterbalanced by the substantial benefits. Notably, the enhanced yields and increased processing capacity directly contribute to higher revenue streams. Furthermore, the operational cost savings achieved through more efficient processes and reduced solvent use contribute significantly to offsetting the initial expenses, presenting a compelling economic case for the adoption of this technology.


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