Ultrasonic topic: "Ultrasonic Processing in the Pharma Industry"
Power ultrasonics is a highly efficient and reliable tool for the production of vaccines, nano-formulated drugs and drug carriers (e.g. liposomes). Hielscher Ultrasonics’ lab, pilot and industrial systems produce pharma-grade micron- and nano-emulsions / -dispersions, liposomes as well as vaccines. Hielscher’s ultrasonic systems are equipped with CIP (clean-in-place) and SIP (sterilize-in-place) and guarantee thereby safe and efficient production according to pharmaceutical standards. All specific ultrasonic processes can be easily tested in lab or bench-top scale and then be linearly scaled up to industrial production.
Found 63 hits. Showing results 49 - 60.
Ultrasonic Avocado Oil Extraction
Ultrasonic extraction and malaxation increases yield of extra virgin avocado oil production. Sonication is a gentle non-thermal process and thereby is appropriate to produce the highest grade of extra virgin avocado oil. The ultrasonically assisted oil pressing not only improves…
https://www.hielscher.com/ultrasonic-avocado-oil-extraction.htm
Ultrasonic Psilocybin Extraction from Mushrooms
Psilocybin is the hallucinogenic substance present in magic mushrooms. For convenient consumption and reliable dosing, psilocybin is normally extracted and used in form of tinctures or enriched foods. As ultrasonic extraction gives high psilocybin yield in a very rapid extraction…
https://www.hielscher.com/ultrasonic-psilocybin-extraction-from-mushrooms.htm
Ultrasonic Preparation of Platelet Rich Serum
Platelet-rich plasma (PRP) is blood plasma that has been enriched with platelets, which is used for medical and estethic treatments. Ultrasonic lysis and conditioning is an very effective method to prepare platelet-rich plasma. Hielscher Ultrasonics offers various ultrasonic systems matching…
https://www.hielscher.com/ultrasonic-preparation-of-platelet-rich-serum.htm
Surfactant-Free Cosmetic Emulsions by Power Ultrasonics
Due to the increasing demand for eco-friendly cosmetics, the cosmetic industry is focussing on the formulation of surfactant-free emulsions. Pickering emulsions are surfactant-/emulsifier-free w/o- or o/w-mixtures stabilized by particles. Ultrasonic mixing and emulsification is an excellent technique to formulate highly…
https://www.hielscher.com/surfactant-free-cosmetic-emulsions-by-power-ultrasonics.htm
Ultrasonic-Enzymatic Diacylglycerol Production
Diacylglycerol (DAG) rich oils have shown a high nutritional value since they are digested and metabolized in a way, which significantly reduces body weight. Diacylglycerol can be produced by the hydrolysis of palm oil using a commercial lipase as a…
https://www.hielscher.com/ultrasonic-enzymatic-diacylglycerol-production.htm
Ultrasonic High Speed Batch Mixers
Wetting, hydration, homogenization, grinding, dispersion, emulsification and dissolving are common applications for Hielscher's ultrasonic high speed batch mixers. Ultrasonic batch mixing is carried out at high speed with reliable, reproducible results for outstanding process results at lab, bench-top and full…
https://www.hielscher.com/ultrasonic-high-speed-batch-mixers.htm
Closed Ultrasonic Reactor for Pharmaceutical Batch Processing
Many processes as mixing, dispersing and extraction of high-value materials are carried out as batch process. Hielscher's closed ultrasonic reactor is ideal for an integrated ultrasonic processing under closed and precisely controlled conditions. Hielscher's closed ultrasonic reactor is perfectly suitable…
https://www.hielscher.com/closed-ultrasonic-reactor-for-pharmaceutical-batch-processing.htm
Sonofragmentation – The Effect of Power Ultrasound on Particle Breakage
Sonofragmentation describes the breakage of particles into nano-sized fragments by high power ultrasound. In contrast to the common ultrasonic deagglomeration and milling - where particles are mainly grinded and separated by inter-particle collision - , sono-fragementation is distinguished by the…
https://www.hielscher.com/sonofragmentation-the-effect-of-power-ultrasound-on-particle-breakage.htm
Ultrasonic Treatment of Nanoparticles for Pharmaceuticals
Probe-type sonicators play a crucial role in pharmaceutical research and manufacturing by providing a powerful and controlled means of achieving particle size reduction, cell disruption, and homogenization. Sonicators utilize ultrasonic waves to generate cavitation, resulting in the formation and collapse…
https://www.hielscher.com/ultrasonic-treatment-of-nanoparticles-for-pharmaceuticals.htm
Ultrasonication Accelerates the Suzuki Coupling Reaction
The Suzuki Cross-Coupling (also known as Suzuki-Miyaura Coupling) is an organic reaction with the aim to synthesize biphenyl derivatives, vinyl aromates (e.g. styrenes), poly-olefins, as well as alkyl bromides. The reaction base materials are an aryl- or vinyl-boronic acid with…
https://www.hielscher.com/ultrasonication-accelerates-the-suzuki-coupling-reaction.htm
Ultrasonically Assisted Fermentation for Bioethanol Production
Ultrasonically-assisted fermentation can enhance bioethanol production by promoting the breakdown of complex carbohydrates into simpler sugars, making them more readily available for yeast to convert into ethanol. Simultaneously, sonication also improves the efficiency of yeast cell wall permeability, allowing for…
https://www.hielscher.com/ultrasonically-assisted-fermentation-for-bioethanol-production.htm
Ultrasonically Induced and Enhanced Phase Transfer Catalysis
High power ultrasound is well-known for its contribution to various chemical reactions. This is the so-called sonochemistry. Heterogeneous reactions – and especially phase transfer reactions – are highly potential application fields for power ultrasound. Due to the mechanical and sonochemical…
https://www.hielscher.com/ultrasonically-induced-and-enhanced-phase-transfer-catalysis.htm