Ultrasonic topic: "Ultrasonic Cell Disruption"
Cell disruption is a technique or process used to release and isolate biological molecules from inside a cell. Ultrasonication is a highly efficient method to perforate and disrupt cell walls and membranes so that the intracellular material and the targeted biomolecules are released into the solvent. As a non-thermal, mild , yet highly efficient technique, ultrasonic disruptors are used in lab and industry to lyse cells and to produce superior extracts. Ultrasonic cell disruptors are used to prepare DNA and RNA as well as to extract bioactive compounds such as vitamins, polyphenols or natural pigments.
Read more about the manifold applications of ultrasonic cell disruption and extraction!
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GDmini2 – Ultrasonic Inline Micro-Reactor
The GDmini2 is an ultrasonic micro-reactor for the indirect, temperature-controlled sonication of liquid media. Applications include: Homogenization, emulsification, particle synthesis, solvent extraction, cell lysis and fragmentation. The GDmini2 is an ultrasonic homogenizer in the shape of a straight glass tube.…
https://www.hielscher.com/gdmini2-ultrasonic-inline-micro-reactor.htmClosed Ultrasonic Reactor for Pharmaceutical Batch Processing
Many processes as mixing, dispersing and extraction of high-value materials are carried out as batch process. Hielscher's closed ultrasonic reactor is ideal for an integrated ultrasonic processing under closed and precisely controlled conditions. Hielscher's closed ultrasonic reactor is perfectly suitable…
https://www.hielscher.com/closed-ultrasonic-reactor-for-pharmaceutical-batch-processing.htmUltrasonic Tissue Homogenizers
Ultrasonication is a safe & efficient method of tissue homogenization. Ultrasonic applications include the preparation tissue and suspensions, the extraction of proteins, DNA/ RNA and active compounds, as well as the activation / inactivation of enzymes and yeasts. The precise…
https://www.hielscher.com/ultrasonic-tissue-homogenizers.htmSonication for Cell Lysis: Cell Disruption and Extraction
Ultrasonic cell lysis is a widely applied sample‑preparation technique in modern biotech laboratories. Its primary purpose is to disrupt cellular membranes or entire cells in order to release intracellular components such as proteins, nucleic acids, or organelles. In daily lab…
https://www.hielscher.com/ultrasonic-lysis-cell-disruption-extraction.htmUltrasonically Assisted Saffron Extraction
Ultrasound is well known for its extraction capacity. The ultrasonically assisted extraction of active compounds, flavours and spices from plant material is a very successful application as ultrasonically generated cavitation disruptes plant cells and enhances mass transfer so that the…
https://www.hielscher.com/ultrasonically-assisted-saffron-extraction.htmPower Ultrasound for the Improvement of Juices & Smoothies
Researches from the Technical University Berlin found that ultrasonication is a very effective processing method to improve fruit and vegetable juices as well as smoothies. Being a non-thermal food process technique, ultrasound provides a mild but effective treatment that intensifies…
https://www.hielscher.com/power-ultrasound-for-the-improvement-of-juices-smoothies.htmAlgae Grow Lab – Ultrasonic Algae Extraction
Algae Cultivation Algae Grow Lab developed a series of tubular and flat photobioreactors for algae cultivation as well as a process of cell ultrasonic destruction based on Hielscher ultrasonic processors equipped with flow cells. The general flow diagram of the…
https://www.hielscher.com/algae-grow-lab.htmUltrasonic Extraction and Preservation
Ultrasonic extraction and preservation utilizes using power ultrasound for the disintegration of cell structures (lysis). Breaking cells with ultrasonics results in highly efficient extraction of intra-cellular compounds as well as microbial inactivation. Due to numerous advantages, ultrasonication is widely used…
https://www.hielscher.com/extraction_01.htmUltrasonic Homogenizers
Ultrasonic homogenizers are powerful tools to mix and homogenize solid-liquid and liquid-liquid suspensions. Ultrasonic homogenization is a mechanical process to reduce particles in a liquid so that they become uniformly small and evenly distributed. Hielscher offers powerful ultrasonic homogenizers for…
https://www.hielscher.com/homogenize_01.htmUP200H / UP200S – Ultrasonic Power for the Lab
The ultrasonic lab devices UP200H (200W, 24kHz) and UP200S (200W, 24kHz) are well suited for all general ultrasonic applications in small and medium scale. The applications include: Homogenization, disintegration, emulsification, cell disruption, degassing or sonochemistry. The production of these models…
https://www.hielscher.com/200s_p.htmUP50H – Compact Lab Homogenizer
The ultrasonic processor UP50H is typically used for the sonication of small lab samples. This homogenizer allows for the handheld or stand-mounted emulsification, dispersing, dissolving or cell disruption. The ultrasonic processor UP50H (50 watts, 30kHz) is the smallest model of…
https://www.hielscher.com/50h_p.htmUltrasonic Disintegration of Cells
Ultrasonication is an effective means of disintegrating cell structures. Therefore, sonicators are widely used in laboratories to break open cells, extract intracellular molecules, proteins and organelles for research and analysis. On industrial scale, ultrasonic disintegration and lysis is used to…
https://www.hielscher.com/cell_disintegration_01.htm










