Utrasonic topic: "Ultrasonic Cell Disruption"
Cell disruption is a technique or process used to release and isolate biological molecules from inside a cell. Ultrasonication is a highly efficient method to perforate and disrupt cell walls and membranes so that the intracellular material and the targeted biomolecules are released into the solvent. As a non-thermal, mild , yet highly efficient technique, ultrasonic disruptors are used in lab and industry to lyse cells and to produce superior extracts. Ultrasonic cell disruptors are used to prepare DNA and RNA as well as to extract bioactive compounds such as vitamins, polyphenols or natural pigments.
Read more about the manifold applications of ultrasonic cell disruption and extraction!

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Sonication Devices for your Lab Tasks
Sonication devices, particularly probe-type sonicators, are highly specialized tools widely employed in both laboratory and industrial settings. These instruments harness the power of ultrasound to efficiently process various materials. By transmitting ultrasonic energy through a probe (or horn) into a…
https://www.hielscher.com/sonication-devices-for-your-lab-tasks.htmVideo: Multi-Sample Sonicator
Effortless Chromatin, DNA, RNA, and Protein Shearing with Unmatched Consistency. The UIP400MTP multi-sample sonicator delivers superior sonication performance with short processing times, outstanding uniformity and at minimal operating costs. The Hielscher UIP400MTP multi-sample sonicator is a versatile, high-performance ultrasonic…
https://www.hielscher.com/video-multi-sample-sonicator.htmVideo: Botanical Extraction
In this presentation we explain botanical extraction. We explain the challenges of producing high-quality botanical extracts and how a sonicator can help you to overcome these challenges. This presentation will show you how ultrasonic extraction works. You will learn,…
https://www.hielscher.com/video-botanical-extraction.htmUltrasonic Lysis: Step-by-Step Guide to Perfecting Cell Disruption
Do you want to master the science of cell lysis? Look no further! In this step-by-step guide, we will walk you through the process of ultrasonic cell disruption and ensure that your cell lysis technique gets you optimal results. Whether…
https://www.hielscher.com/ultrasonic-lysis-step-by-step-guide-to-perfecting-cell-disruption.htmAgeing and Oaking of Wines with Ultrasound
Wine ageing and oaking contribute heavily to the final taste and quality of wine. Both processes are known to undertake long time, often the maturation process goes over serval years. Ultrasound is a highly efficacious and rapid technology, which intensifies…
https://www.hielscher.com/ageing-and-oaking-of-wines-with-ultrasound.htmPolyphenol-Rich Wines with Power-Ultrasound
Ultrasonication improves the extraction of phenolic compounds from grape to must, which contributes to the total polyphenol content - thereby improving the further ageing process of wine. The application of power ultrasound gives higher extraction yields and accelerates the maturation…
https://www.hielscher.com/polyphenol-rich-wines-with-power-ultrasound.htmUltrasonication Outcompetes Other Extraction Methods by Speed
The rapid procedure of ultrasonic extraction and the therefrom resulting time savings in extract production are one of many advantages of ultrasonic extraction of bioactive compounds from plants. Ultrasonic extraction has been scientifically compared to alternative extraction techniques such as…
https://www.hielscher.com/ultrasonication-outcompetes-other-extraction-methods-by-speed.htmUltrasonic Lysis of Bioengineered Cells in Industrial Production
Bioengineered bacteria species such E. coli as well as genetically modified mammalian and plant cell types are used widely in biotech to express molecules. In order to release these synthesized bio-molecules, a reliable cell disruption technique is required. High-performance ultrasonication…
https://www.hielscher.com/ultrasonic-lysis-of-bioengineered-cells-in-industrial-production.htmUltrasonic DNA Fragmentation for Next Gen Sequencing
Next Generation Sequencing (NGS) requires the reliable shearing and fragmentation of genomic DNA in order to sequence genomic DNA strands and to create genome libraries. The controlled fragmentation of DNA into DNA fragments is an essential sample preparation step required…
https://www.hielscher.com/ultrasonic-dna-fragmentation-for-next-gen-sequencing.htmUltrasonication to Improve Algae Cell Disruption and Extraction
Algae, macro- and microalgae, contain many valuable compounds, which are used as nutritional foods, food additives or as fuel or fuel feedstock. In order to release the target substances from the algae cell a potent and efficient cell disruption technique…
https://www.hielscher.com/ultrasonication-to-improve-algae-cell-disruption-and-extraction.htmUltrasonic Lysis of Drosophila Melanogaster Samples
Drosophila melanogaster is widely used in laboratories as model organism. Therefore, pre-analytical preparation steps such as lysis, cell disruption, protein extraction and DNA shearing of Drosophila melanogaster samples must be frequently carried out. Ultrasonic dismembrators are reliable and efficient and…
https://www.hielscher.com/lysis-of-drosophila-melanogaster-samples.htm96-Well Plate Sonicator UIP400MTP for High-Throughput Sample Prep
96-well plates, microplates, multi-well plates, microtiter plates or ELISA plates are used for the mass sample cultivation and processing of biological samples. With the microtiter plate ultrasonicator UIP400MTP, Hielscher offers a unique ultrasonic solution of the uniform and reliable sample…
https://www.hielscher.com/microtiter-plate-mass-sample-preparation-by-ultrasonication.htm