Ultrasonic topic: "Ultrasonic Cell Disruption"
Cell disruption is a technique or process used to release and isolate biological molecules from inside a cell. Ultrasonication is a highly efficient method to perforate and disrupt cell walls and membranes so that the intracellular material and the targeted biomolecules are released into the solvent. As a non-thermal, mild , yet highly efficient technique, ultrasonic disruptors are used in lab and industry to lyse cells and to produce superior extracts. Ultrasonic cell disruptors are used to prepare DNA and RNA as well as to extract bioactive compounds such as vitamins, polyphenols or natural pigments.
Read more about the manifold applications of ultrasonic cell disruption and extraction!
Found 51 hits. Showing results 1 - 12.
Yeast Cell Lysis in Microplates Using High-Intensity Sonication
Microbiologists and life science researchers working with Saccharomyces cerevisiae, Pichia pastoris / Komagataella phaffii, and other yeast systems know the challenge: yeast cells are robust, reproducible lysis can be difficult, and manual sample disruption quickly becomes a bottleneck when many…
https://www.hielscher.com/yeast-cell-lysis-in-microplates-using-high-intensity-sonication.htm
Microplate Sonication in Shotgun Proteomics – Application Note
Shotgun proteomics depends on efficient, reproducible sample preparation to convert complex biological material into LC-MS/MS-ready peptides. The UIP400MTP microplate sonicator supports this process by enabling standardized, parallel sonication of small-volume samples, helping laboratories improve disruption, extraction, and resolubilization in microplate-based…
https://www.hielscher.com/microplate-sonication-in-shotgun-proteomics.htm
Sonication-Assisted Protein Extraction from Tumor Tissue – Protocol
This protocol describes a sonication-assisted protein extraction method for tumor tissue that advances the standard CPTAC urea lysis workflow by adding a controlled probe-sonication step during tissue disruption. Building on the established deep-scale CPTAC proteome and phosphoproteome preparation strategy, this…
https://www.hielscher.com/sonication-protein-extraction-from-tumor-tissue-protocol.htm
Probe-Type Sonicators for Reliable Lab Workflows
Hielscher Ultrasonics offers a comprehensive range of lab probe sonicators and ultrasonic lab homogenizers designed to meet the diverse needs of research, quality control, process development, and small-scale production. From compact devices for small sample volumes to high-power sonicators for…
https://www.hielscher.com/lab-probe-sonicators.htm
Hybrid Ultrasonics: Mano-, Thermo- and Electro-Sonication
Hybrid ultrasonics combines high-power sonication with controlled pressure, temperature, and electric fields to extend ultrasonic processing beyond conventional limits. By tuning cavitation intensity, reaction kinetics, and transport phenomena, hybrid ultrasonics enables faster extraction, finer emulsions, stronger dispersion, higher electrochemical efficiency,…
https://www.hielscher.com/hybrid-ultrasonics.htm
Video: Sonication of Carrot Juice for Stability and Better Taste
This video demonstrates how sonication stabilizes fresh organic carrot juice by disrupting cell structures and releasing flavors, shown via a refrigerated time-lapse. Using a purely mechanical process, Hielscher sonicators enhance stability, texture, and shelf life of juices, smoothies, purees,…
https://www.hielscher.com/video-sonication-of-carrot-juice-for-stability-and-better-taste.htm
Video: UP200Ht and UP200St – Lab Sonicators
This video features the Hielscher 200 Watts sonicators UP200Ht and UP200St with a digital touch interface to deliver precise, reproducible homogenization with integrated temperature monitoring. For more information about these sonicators, please click here!
https://www.hielscher.com/video-up200ht-and-up200st-lab-sonicators.htm
Sonication Devices for your Lab Tasks
Sonication devices, particularly probe-type sonicators, are highly specialized tools widely employed in both laboratory and industrial settings. These instruments harness the power of ultrasound to efficiently process various materials. By transmitting ultrasonic energy through a probe (or horn) into a…
https://www.hielscher.com/sonication-devices-for-your-lab-tasks.htm
Video: Multi-Sample Sonicator
Effortless Chromatin, DNA, RNA, and Protein Shearing with Unmatched Consistency. The UIP400MTP multi-sample sonicator delivers superior sonication performance with short processing times, outstanding uniformity and at minimal operating costs. The Hielscher UIP400MTP multi-sample sonicator is a versatile, high-performance ultrasonic…
https://www.hielscher.com/video-multi-sample-sonicator.htm
Video: Botanical Extraction
In this presentation we explain botanical extraction. We explain the challenges of producing high-quality botanical extracts and how a sonicator can help you to overcome these challenges. This presentation will show you how ultrasonic extraction works. You will learn,…
https://www.hielscher.com/video-botanical-extraction.htm
Ultrasonic Lysis: Step-by-Step Guide to Perfecting Cell Disruption
Do you want to master the science of cell lysis? Look no further! In this step-by-step guide, we will walk you through the process of ultrasonic cell disruption and ensure that your cell lysis technique gets you optimal results. Whether…
https://www.hielscher.com/ultrasonic-lysis-step-by-step-guide-to-perfecting-cell-disruption.htm
Ageing and Oaking of Wines with Ultrasound
Wine ageing and oaking contribute heavily to the final taste and quality of wine. Both processes are known to undertake long time, often the maturation process goes over serval years. Ultrasound is a highly efficacious and rapid technology, which intensifies…
https://www.hielscher.com/ageing-and-oaking-of-wines-with-ultrasound.htm