Ultrasonics for Vaccine Production

Ultrasonic Vaccine Production

For the preparation of vaccines, including inactivated, attenuated, protein subunit or conjugate vaccines, cells have to be either inactivated, lysed or killed. With the appropriate dose and intensity of sonication, cells and microbes can be treated in accordance to the process goal.

Apply ultrasonic waves to:

• disrupt and lysate cells
• inactivate viral and bacterial cells
• release of intracellular material, e.g. proteins, antigens
• stimulate bacterial activity
• prepare nano drug carriers
• activate/ inactivate enzymes
• prepare nano-emulsions and double emulsions

Ultrasonic Vaccine Preparation on Lab and Industrial Scale

Hielscher Ultrasonics offers a broad range of ultrasonic devices from lab scale to full industrial grade equipment for commercial production. We cover your needs from small ultrasonicators for your research department up to the full-stream processing of your commercially produced pharmaceuticals.

Reliable and Adjustable to Your Application Needs

By adjusting the parameters of ultrasonic processing, the effects of sonication can be precisely controlled. This means that a low amplitude and short sonication has very soft effects, while high amplitudes, elevated pressure and longer sonication duration results in intense processing.
Hielscher supplies powerful ultrasonic devices that can be precisely controlled in accordance to the process requirements. Manifold sonotrodes and accessories complete the offering.

Safe and Clean

Hielscher’s ultrasonicators can be easily installed in cleanroom laboratories and production facilities. The housings of our devices are made from antibacterial plastic or stainless steel. All wetted parts, such as our sonotrodes and flow cells, are made from titanium or stainless steel and can be autoclaved.
Hielscher Ultrasonics offer a manifold range of standard devices and accessories as well as customized equipment.

Advantages