Universal Compatibility: Sonicate Multi-well Plates with the UIP400MTP

The UIP400MTP multi‑well plate sonicator is engineered for universal compatibility, enabling efficient, non‑contact ultrasonic processing across virtually all standardized microplate formats without the need for proprietary consumables. It accepts and operates seamlessly with 6‑, 12‑, 24‑, 48‑, 96‑, and 384‑well plates, regardless of whether they have flat, U‑, V‑, or round bottoms and are coated or uncoated.

Optimize Your Workflow with the UIP400MTP Multiwell Plate Sonicator

• Cell & Tissue Lysis
  Effective disruption of mammalian, bacterial, yeast, plant cells, fresh frozen or FFPE tissue – ideal for DNA/protein extraction (genomics, NGS, proteomics).
• Nucleic Acid Shearing
  Controlled fragment lengths (e.g. for NGS libraries) with high reproducibility.
• Cell Detachment
  Excels the gold standard of cell scraping: The UIP400MTP effectively detaches and dislodges cells from plates.
• Protein Extraction & Homogenization
  Reliable extraction from cell cultures or tissue; excellent for downstream proteomics.
• Assay Mixing, Biofilm Removal
  Enhances ELISA reagent mixing; biofilm dislodging in micro cavity plates.
• PCR / qPCR Workflows
  Sonication inside PCR plates aids cell lysis, reagent blending, pathogen DNA prep.

Efficiency & Throughput

Powerful simultaneous, uniform non-contact sonication of 1 – 384 wells with the UIP400MTP offers a distinct advantage over bead beating, enzymatic kits or ultrasonic baths.
Contact-less sonication avoids plate-to-plate or well-to-well cross-contamination; sealed plates or foil covers avoid sample loss and contamination.
Programmable settings save valuable time and avoid human error, thereby streamlining workflows and enabling automation

Frequently Asked Questions about Multi-well Plates

What are the Formats of Multiwell Plates?

Multiwell plates are manufactured in standardized formats such as 6‑, 12‑, 24‑, 48‑, 96‑, 384‑, and 1536‑well configurations, allowing parallel processing and compatibility with automated systems.

What are the Different Types of Microplates?

Microplates vary by material, surface treatment, and design, including cell‑culture treated plates, non‑treated assay plates, filter plates, deep‑well plates, PCR plates, and specialized low‑attachment or high‑binding surfaces.

What are Multiwell lates?

Multiwell plates are flat plates containing multiple small wells arranged in a matrix, used as standardized vessels for high‑throughput biological, chemical, or analytical assays.

What are the Different Types of 96‑Well Plates?

Common 96‑well variants include flat‑bottom, U‑bottom, and V‑bottom designs, available in clear, black, or white polymers, with options for tissue‑culture treatment, low‑attachment coatings, or specialized optical properties.

What are Cell Culture Plates?

Cell culture plates are standardized, sterile plastic plates–typically polystyrene–that contain multiple wells designed to support the attachment, growth, and maintenance of cells under controlled laboratory conditions.
They are produced with specific surface treatments (for example, tissue‑culture treated surfaces that promote cell adhesion) or specialized coatings such as extracellular matrix proteins, ultra‑low attachment (ULA) coatings for spheroid formation, or micropatterned surfaces to guide cell behavior.
Cell culture plates are available in multiwell formats (e.g., 6‑, 12‑, 24‑, 48‑, and 96‑well) and are compatible with standard incubators, imaging systems, and liquid handling platforms.

What are 3D Cell Cultures?

3D cell cultures are in vitro systems where cells are grown within a three‑dimensional matrix or scaffold, allowing them to form tissue‑like architectures and cell–cell/extracellular matrix interactions that closely mimic in vivo physiology.

Literature / References