Hielscher Ultrasonics
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Video: UIP400MTP – Uniform Microplate Sonication

An aluminum foil erosion test shows the uniform cavitation erosion of the aluminum foil in the area of the multi-well plates to be sonicated. Another test shows the emulsification of clear oil and water in all wells of the 96-well plate.

UIP400MTP for Multi-Well-Plate Sonication - Ultrasonic Intensity Uniformity

 

The UIP400MTP microplate sonicator delivers uniform sonication results within short processing times.
The multi-well plate sonicator UIP400MTP demonstrates remarkable uniformity of ultrasonic energy distribution across all wells, as validated by standardized test procedures. In the video, a thin sheet of aluminum foil is sonicated, and the cavitation effect produces evenly distributed pitting marks over the entire foil, confirming homogeneous acoustic intensity. In a subsequent test, a 96‑well plate containing a biphasic mixture is sonicated, and each well rapidly forms a stable and visually identical emulsion. These results underscore that every well – whether in small‑scale assays or high‑throughput workflows – receives the same level of ultrasonic energy, ensuring reproducible processing conditions and highly consistent experimental outcomes.

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Multi-Sample Sonication

The Hielscher UIP400MTP is a versatile and powerful sonicator designed for multi-well plates, PCR plates, and sample tubes. With 400 watts of continuous output power, it excels in applications such as cell lysis, protein extraction, DNA/RNA fragmentation, and nanomaterial dispersion, delivering uniform sonication across all wells. The UIP400MTP offers precise control over key parameters, built-in temperature monitoring, and 24/7 operational capability, making it ideal for high-throughput workflows in demanding lab environments.

Sonicator for Multi-Well Plates - Hielscher UIP400MTP - 400 Watts Ultrasonic Power

High Throughput Sonication

The Hielscher UIP400MTP is a high-throughput sonicator designed for multi-well plates and vial holders, delivering up to 50 times the intensity of an ultrasonic bath. With 400 watts of power, it excels in applications like cell disruption, protein extraction, DNA fragmentation, and sample homogenization, offering unmatched uniformity and ease of use. Built for precision and reliability, it features temperature control, automated data logging, and 24/7 operation, making it an indispensable tool for analytical and research labs worldwide.

Multi-Well-Plate Sonicator for High Throughput Sample Preparation

Multi-Sample Uniformity

The UIP400MTP sonicator is designed for multi-well and microtiter plates, delivering exceptionally uniform ultrasonic intensity across all wells. Real-time tests, such as aluminum foil erosion and oil-water emulsification, demonstrate its consistent cavitation and emulsification effects in every well of a 96-well plate. This ensures identical results for applications like dispersion, homogenization, extraction, emulsification, and DNA shearing across all wells.

Multi-Well-Plate Sample Sonication Uniformity

We will be glad to discuss your process.