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Sterile Sonication of Falcon Tubes

The VialTweeter VT26dxx is an ultrasonic sample homogenizer designed specifically for Falcon tubes. The VialTweeter VT26dxx sonicates the sample in a Falcon tube indirectly, avoiding the insertion of an ultrasonic probe into the sample. This allows cross-contamination and sample loss completely marking a significant advancement in biological sample processing. By offering precise control over processing parameters such as amplitude, temperature and duration, the VT26dxx enhances quality and reliability in sample preparation

Sonication of Samples in Falcon Tubes

The Hielscher VT26dxx is an indispensable tool for laboratories that frequently work with Falcon tubes. The VT26dxx is a highly reliable, consistent, and contamination-free method for sonication of samples in Falcon tubes. By offering precise energy control, reducing contamination risks, and improving sample homogeneity, the Hielscher VialTweeter VT26dxx for Falcon tubes outperforms traditional ultrasonic baths in virtually every aspect.

The VialTweeter model VT26dxx is designed for the sterile sonication of samples in Falcon tubes.

The VialTweeter model VT26dxx is designed for the sterile sonication of samples in Falcon tubes

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Sonicator UP200St with VialTweeter VT26dxx for the sterile sonication of single vials such as Falcon Tubes

Sonicator UP200St with VialTweeter VT26dxx for the sterile sonication of single test tubes such as Falcon tubes

 

n this video, we showcase a specialized version of the Hielscher VialTweeter (https://www.hielscher.com/VT) designed for sonication of closed sample vials. The standard Hielscher VialTweeter is an essential tool in biotech research and sample preparation for analyzing a diverse range of laboratory samples. This device enables intensive, consistent, and reproducible sonication of up to 10 closed sample vessels simultaneously. This capability facilitates high-throughput processes such as cell disruption, DNA fragmentation, emulsification, dispersion, and degassing, all achieved with short sonication times. For sample vessels that don't fit the standard VialTweeter, Hielscher Ultrasonics offers custom larger or smaller versions, accommodating one to ten specialized sample vessels.

Ultrasonication of Closed Sample Vials - The Hielscher VialTweeter

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As research demands grow and evolve, this homogenizer exemplifies the forward-thinking design needed to meet the challenges of modern biological research. Researchers can look forward to achieving faster, more accurate results while preserving the quality and integrity of their valuable biological samples.

VT26dxx – Applications and Advantages

The VialTweeter model VT26dxx for ultrasonic sample homogenization in Falcon tubes is particularly advantageous in a variety of biological research applications, including:

  • Tissue Homogenization: For extracting RNA, DNA, or proteins from tissues, uniform and effective homogenization is essential. The ability of this homogenizer to break down tough tissues – such as muscle, liver, or plant material – within Falcon tubes makes it a valuable tool for genomics and proteomics studies.
  • Cell Suspensions and Microbial Cultures: Researchers working with microbial cultures or cell suspensions will appreciate the ability to quickly and uniformly resuspend cells after centrifugation. The gentle agitation settings also make it suitable for fragile cells that need to be kept intact.
  • Enzyme Reactions and Drug Studies: Homogenizing biological samples in drug discovery or enzymatic reaction studies ensures that the entire sample is consistently exposed to treatment, enhancing the accuracy and reproducibility of results.
  • Stem Cell Isolation: The indirect, yet intense sonication is ideal to isolate stem cells from adipose tissue under clinical conditions.
  • Protein Purification: Indirect sonication provides the energy necessary to lyse cells while maintaining protein integrity, ensuring more efficient purification processes.
  • Nanoparticle Dispersion: Uniform sonication energy is essential for the even dispersion of nanoparticles, and the Hielscher device delivers this consistency without the risk of contamination from probe contact.
  • Emulsification: Indirect sonication with the Hielscher device facilitates the creation of stable emulsions, useful in pharmaceutical and cosmetic research.
Powerful sample homogenization without cross-contamination and sample loss is reliably achieved using the VialTweeter VT26dxx.

VialTweeter VT26dxx for ultrasonic sample homogenization under sterile conditions

The VialTweeter-spec VT26dxx reliably sonicates single vials and test tubes such as Falcon tubes for sample homogenization, cell disintegration, protein extraction etc.

Sterile sonication of single test tubes with the VialTweeter VT26dxx

VialTweeter Sonicator for Sterile Sample Preparation

The VialTweeter offers a distinctive approach to single vial sonication, delivering powerful and reliable results that are essential for both research and clinical analysis. Its engineering, rooted in German quality, ensures durability and precision, setting it apart from other sonicators in the market. The ultrasonic sterile homogenizer is designed with customization in mind, allowing users to tailor it to their specific needs, which enhances usability and effectiveness. Additionally, Hielscher Ultrasonics is committed to exceptional customer service, ensuring that users receive the support they need for optimal performance. This combination of robust functionality, reproducible results, and dedicated service makes the VialTweeter a top choice for those requiring effective sonication solutions.

Design, Manufacturing and Consulting – Quality Made in Germany

Hielscher ultrasonicators are well-known for their highest quality and design standards. Robustness and easy operation allow the smooth integration of our ultrasonicators into industrial facilities. Rough conditions and demanding environments are easily handled by Hielscher ultrasonicators.

Hielscher Ultrasonics is an ISO certified company and put special emphasis on high-performance ultrasonicators featuring state-of-the-art technology and user-friendliness. Of course, Hielscher ultrasonicators are CE compliant and meet the requirements of UL, CSA and RoHs.

Ask for more information

Please use the form below to request additional information about the VialTweeter VT26dxx for single Falcon tubes, application details and price. We will be glad to discuss your sample preparation with you and to offer you an ultrasonic system fulfilling your requirements!









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This tutorial explains what type of sonicator is best for your sample preparation tasks such as lysis, cell disruption, protein isolation, DNA and RNA fragmentation in laboratories, analysis, and research. Choose the ideal sonicator type for your application, sample volume, sample number and throughput. Hielscher Ultrasonics has the ideal ultrasonic homogenizer for you!

How to Find the Perfect Sonicator for Cell Disruption and Protein Extraction in Science and Analysis

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Literature / References

Frequently Asked Questions

What is a Falcon Tube?

A Falcon tube is a type of conical centrifuge tube commonly used in laboratories for the storage and centrifugation of biological samples, such as cells, tissues, and fluids. Typically made from plastic, these tubes are available in various sizes, often ranging from 15 to 50 milliliters, and feature a screw-cap lid to prevent leakage. They are designed to withstand the forces generated during centrifugation and are often used in molecular biology, microbiology, and biochemistry applications for sample preparation and processing.

Where does the Name “Falcon Tube” come from?

The name “Falcon Tube” comes from the brand name of the product manufactured by Becton, Dickinson and Company (BD). The term originated in the 1960s when BD introduced these conical centrifuge tubes, and they became widely recognized in scientific and laboratory settings. The brand name “Falcon” is now often used generically to refer to similar types of centrifuge tubes, regardless of the manufacturer.


High performance ultrasonics! The Hielscher product range covers the full spectrum from the compact lab ultrasonicator over bench-top units to full-industrial ultrasonic systems.

Hielscher Ultrasonics manufactures high-performance ultrasonic homogenizers from lab to industrial size.

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