Ultrasonic topic: "Ultrasonic Lysis and Cell Disruption"
Lysis is the term which describes the disruption of cell walls or membranes. Ultrasonic disruptors are a reliable tool to break cells in order to release intracellular compounds such as DNA, proteins, organelles, and phytochemicals. For ultrasonic lysis (aka cell disruption), high-intensity / low-frequency ultrasound waves are applied to disrupt the cell membranes. Since ultrasonication promotes mass transfer, the intracellular material is released into the surrounding solvent. The fluid containing the contents of lysed cells is called a lysate.
Cell lysis is the first step in cell fractionation, organelle isolation and protein extraction and purification.
Read more about ultrasonic cell disruptors and ultrasonic lysis!
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Ultrasonic Processor UIP2000hd – High-Efficiency
The ultrasonic processor UIP2000hd (20kHz, 2000W) is a powerful and adaptable ultrasonic device for the industrial processing of liquids. It is used for applications, such as emulsification, dispersing & particle fine milling, lysis & extraction or homogenizing. Despite the enormous…
https://www.hielscher.com/i2000_p.htmUIP500hdT – Industrial Processing in Small Scale
The ultrasonic processor UIP500hdT (20kHz, 500W) is an industrial grade device for pilot testing and small scale processing of liquids. Amongst the most common applications of the UIP500hdT are homogenization, dispersing, emulsification, cell disintegration and sonochemical reactions. A full color…
https://www.hielscher.com/i500_p.htmUltrasonic Extraction and Preservation
Ultrasonic extraction and preservation utilizes using power ultrasound for the disintegration of cell structures (lysis). Breaking cells with ultrasonics results in highly efficient extraction of intra-cellular compounds as well as microbial inactivation. Due to numerous advantages, ultrasonication is widely used…
https://www.hielscher.com/extraction_01.htmUltrasonic Homogenizers
Ultrasonic homogenizers are powerful tools to mix and homogenize solid-liquid and liquid-liquid suspensions. Ultrasonic homogenization is a mechanical process to reduce particles in a liquid so that they become uniformly small and evenly distributed. Hielscher offers powerful ultrasonic homogenizers for…
https://www.hielscher.com/homogenize_01.htmUP400S – Powerful Sonication of Larger Samples
400 Watts ultrasonic power - The UP400S (400W, 24kHz) is a powerful and reliable ultrasonic device for the sonication of larger samples in the lab. Typical application include: Homogenization, deagglomeration, lysis and cell disintegration, protein extraction and the emulsification of…
https://www.hielscher.com/400s_p.htmUP50H – Compact Lab Homogenizer
The ultrasonic processor UP50H is typically used for the sonication of small lab samples. This homogenizer allows for the handheld or stand-mounted emulsification, dispersing, dissolving or cell disruption. The ultrasonic processor UP50H (50 watts, 30kHz) is the smallest model of…
https://www.hielscher.com/50h_p.htmUltrasonic Disintegration of Cells
Ultrasonication is an effective means of disintegrating cell structures. Therefore, sonicators are widely used in laboratories to break open cells, extract intracellular molecules, proteins and organelles for research and analysis. On industrial scale, ultrasonic disintegration and lysis is used to…
https://www.hielscher.com/cell_disintegration_01.htmUP100H – Compact Ultrasonic Laboratory Device
The ultrasonic processor UP100H (100W, 30kHz) is the perfect device for the sonication of small and medium size lab samples. This compact, yet powerful, lab homogenizer is commonly used for sample preparation, such as emulsifying, dispersing, dissolving and cell disruption.…
https://www.hielscher.com/100h_p.htm






