Hielscher Ultrasonics
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Ultrasonic topic: "Ultrasonic Lysis and Cell Disruption"

Lysis is the term which describes the disruption of cell walls or membranes. Ultrasonic disruptors are a reliable tool to break cells in order to release intracellular compounds such as DNA, proteins, organelles, and phytochemicals. For ultrasonic lysis (aka cell disruption), high-intensity / low-frequency ultrasound waves are applied to disrupt the cell membranes. Since ultrasonication promotes mass transfer, the intracellular material is released into the surrounding solvent. The fluid containing the contents of lysed cells is called a lysate.
Cell lysis is the first step in cell fractionation, organelle isolation and protein extraction and purification.
Read more about ultrasonic cell disruptors and ultrasonic lysis!

Sonicators as the UP200St are used to prepare genetic material such as DNA, RNA, miRNA and the subsequent gene transfection via sonoporation. Sonoporation allows to transfect plant cells with genetic material using agrobacterium.

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Sonicator UIP1000hdT for nano-dispersion and encapsulation of phase-change materials (PCMs)

Ultrasonic Homogenizers

Ultrasonic homogenizers are powerful tools to mix and homogenize solid-liquid and liquid-liquid suspensions. Ultrasonic homogenization is a mechanical process to reduce particles in a liquid so that they become uniformly small and evenly distributed. Hielscher offers powerful ultrasonic homogenizers for…

https://www.hielscher.com/homogenize_01.htm
Ultrasonic disperser for of specialty inks (Click to enlarge!)

UP50H – Compact Lab Homogenizer

The ultrasonic processor UP50H is typically used for the sonication of small lab samples. This homogenizer allows for the handheld or stand-mounted emulsification, dispersing, dissolving or cell disruption. The ultrasonic processor UP50H (50 watts, 30kHz) is the smallest model of…

https://www.hielscher.com/50h_p.htm

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