50 mL Falcon Tube Sonicator
Falcon Tube Sonication in Microbiology and Formulation
Molecular biologists can rapidly lyse E. coli or yeast cells in closed 50 mL Falcon Tubes using this VialTweeter, preserving sterility and preventing solvent loss. Meanwhile, specialists in the cosmetics and pharmaceutical industries leverage the same powerful sonication to produce stable emulsions or liposomal dispersions with highly consistent droplet sizes. Whether you need enhanced cell disruption, nanoparticle dispersions, or improved product homogeneity, the closed system approach supports a broad range of workflows.
Nanoparticle Sonication and Advanced Materials Research
Many academic labs and research centers rely on this VialTweeter to break up tightly bound nanoparticle agglomerates. By directing high-intensity ultrasonic waves through the wall of a sealed 50 mL Falcon tube, the system creates uniform suspensions of metal oxides, carbon nanotubes, or polymer-based particles. Such precise dispersions benefit cutting-edge research in advanced coatings, battery development, and particle functionalization.
Sonicating Carbon-Nano-Tubes in a Falcon Tube
Sterile Sonication Workflows in Biotech and Pharma
For those requiring aseptic conditions — such as vaccine production or bacterial culture treatment — this Falcon tube sonicator enables sonication without opening the tube. This preserves a controlled environment and supports reproducible results. The polypropylene construction of typical 50 mL conical centrifuge tubes also accommodates a wide range of solvents and reagents, simplifying integration into existing lab protocols.
VialTweeter Sonicator for 50 mL Falcon Tubes.
Inline Sonication and Electrochemical Enhancements
By adding a specialized reactor lid, the 50 mL conical tube becomes an inline sonication system with an inlet at the bottom and outlet at the top. Fluid continuously flows through the cavitation zone, ensuring uniform, high-intensity treatment for applications like flow chemistry or enzymatic reactions.
Ultrasonic Inline Reactor in a 50mL Falcon Tube
Sono-Electro-Chemistry
Another specialized lid transforms the Falcon tube into a sono-electrochemical cell, featuring ports for electrodes, gas discharge, and liquid recirculation. Here, powerful sonication eliminates gas bubbles on the electrode surface, boosting current flow and accelerating electrochemical reactions. Learn more about sono-electrochemistry and its advantages!
Sono-Electro-Chemistry in a 50mL Falcon Tube
Key Advantages
- Powerful cell lysis for microbiological studies (e.g., E. coli, yeast)
- Stable emulsification of liposomal formulations in pharmaceutical research
- Homogenization and dispersal of nanoparticles in advanced materials development
- Sterile workflows for biotech applications (vaccines, bacterial cultures)
- Continuous or recirculating flow chemistry setups for rapid pilot-scale testing
- Sono-electrochemical reactions with enhanced mass transfer and accelerated kinetics
Efficiency and Scale-Up
Researchers can quickly test variables in a 50 mL conical sample vial, then transfer optimized protocols to larger ultrasound reactors with minimal adjustment. This seamless scale-up path shortens the time from laboratory experimentation to full production.
Other Vial Sizes and Microplate Sonication
The Hielscher VialTweeter can be adapted for closed-vessel sonication of many container types, reducing the need for cleaning probes or exposing operators to aerosols. For smaller volumes and higher throughput, the Hielscher UIP400MTP offers efficient sonication of micro-well plates.
The Hielscher VialTweeter for 50 mL Falcon tubes is readily available for all processes. If you require sonication for different sizes or shapes of sample vials, please contact us!