Utrasonic topic: "Ultrasonic liposome production and its advantages"

A liposome is a spherical vesicle with at least one lipid bilayer. Liposomes are widely used as vehicles for drug and nutrient delivery. Due to its composition and size, liposomes offer a great bioavailability and absorption rate in the body. Sonication is the preferred technique to prepare loaded liposomes, such as small, unilamellar vesicles (SUV) with diameters in the range of 15-50nm or large, multilamellar vesicles (LMV) with a size of with a mean diameter of 120-140nm. The majority of liposomes is composed of phospholipids, e.g. phosphatidylcholine, but other lipids, such as egg phosphatidylethanolamine, are successfully used too, if compatible with lipid bilayer structure.
Hielscher ultrasonicators are reliable tools to produce nano-sized liposomes and to formulate liposomal products. To ensure reproducibility and highest quality standards of the liposomal products, Hielscher ultrasonicators can be precisely controlled. The most important ultrasonic process parameters such as amplitude, time, temperature, and pressure can be exactly set and monitored. An integrated SD-card automatically protocols the ultrasonic parameters and facilitates thereby reproducibility and quality control.
Read more about the use of ultrasonic processors for the preparation of liposomes!

Ultrasonication is used to produce liposomes

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超音波抽出は、エッセンシャルオイル、ポリフェノール、フラボノイドおよび他の生理活性代謝産物をStachys parviflora(baggibuti)などの植物から単離するための簡単で効率的かつ迅速な技術です

Ultrasonic Extraction of Polyphenols from Baggibuti (Stachys parviflora)

Baggibuti(Stachys parviflora L.)植物の抽出物は、けいれん、関節痛、てんかん、転倒病、およびドラクンキュリア症の治療に使用される漢方薬として評価されています。超音波抽出器は、Stachys parvifloraからのポリフェノールおよび他の植物化学物質の単離に首尾よく適用されている。…


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