UIP550MTP Microplate Sonicator

The most powerful ultrasonic solution for uniform sonication of 12-, 24-, 48-, 96-, and 384-well plates. Achieve consistent cell lysis, protein extraction, and DNA fragmentation across all wells simultaneously.

UIP550MTP – 550 W Ultrasonic Power for High-Throughput Sample Preparation

96-well plates, microplates, multi-well plates, microtiter plates or ELISA plates are used for the mass sample cultivation and processing of biological samples. With the microtiter plate ultrasonicator UIP550MTP, Hielscher offers a unique ultrasonic solution of the uniform and reliable sample preparation of 12-, 24,-, 48-, 96-, or 384-well plates. Common applications of the microtiter ultrasonicator UIP550MTP include cell lysis, protein extraction, cell homogenization and solubilization as well as DNA fragmentation.

• 550W Ultrasonic Power – the UIP550MTP processes demanding samples with ease
• Kompatibel mat all Standard Multi-Well Plack
• Uniform sonication of each well
• Precisely adjustable amplitudes and advanced temperature control
• Fully automatable for high-throughput workflows

Who is the UIP550MTP Designed for?

For laboratories that already value the UIP400MTP, the UIP550MTP offers the next step: more ultrasonic capacity, more processing intensity, and more confidence when working with difficult samples, higher sample loads, or time-sensitive protocols.

Why Choose the UIP550MTP?

The UIP550MTP is built for buyers who need reliable, scalable, and reproducible microplate sonication. It enables simultaneous treatment of samples across the plate, reducing manual handling and eliminating the inconsistencies associated with probe-by-probe sonication. Since the samples remain in their plates or vessels, the UIP550MTP supports clean, efficient workflows with reduced risk of cross-contamination.
Use the UIP550MTP when you need a powerful microplate sonicator for high-throughput sample preparation, automated laboratory workflows, reproducible assay preparation, biological sample processing, and demanding research or analytical protocols.
 

Choose your own plate! The UIP550MTP works with any standard multi-well plate.

Advantages of the Hielscher Microplate Sonicator UIP550MTP

✅ High-Power, Focused Sonication: Achieving consistent and efficient sample disruption in multiwell plates can be difficult when using traditional methods like plate shakers or bead mills. These techniques often produce inconsistent lysate quality, which can negatively impact downstream applications. The Hielscher microplate sonicator UIP550MTP provides a solution by using high-intensity ultrasound waves to create cavitation, ensuring uniform disruption across all wells and resulting in reliable lysate preparation throughout the plate.

✅ High-Throughput: Scalability is another important factor in multiwell plate sample processing. Traditional equipment is often limited in handling multiple plates, making large-scale processing cumbersome. The UIP550MTP sonicator solves this issue by being compatible with standard plate formats (12-, 24-, 48-, 96-, or 384-wells). Its compact design allows for the easy addition of multiple units, enabling high-throughput sample preparation and simultaneous sonication of multiple plates.

✅ Sterile Sonication: Cross-contamination is a frequent concern with traditional methods, as sample splashing or carryover between wells can compromise data quality. The UIP550MTP minimizes this risk by indirectly sonicating the plates, removing the need for beads or chemicals. By covering the plates with foil or a lid, a closed system is created, preventing cross-contamination.

✅ Käschte-Effizienz: Cost and flexibility are also key considerations. Many high-throughput sonicators require expensive proprietary plates, which limits options and increases costs. The UIP550MTP, however, works with any standard multiwell plate, allowing researchers to choose the most suitable and cost-effective plates for their experiments, reducing expenses on consumables.

✅ Streamlined Workflows: Traditional sample preparation techniques can be labor-intensive, requiring repetitive manual steps and long processing times. The UIP550MTP sonicator simplifies the workflow, reducing hands-on time and labor. It provides fast, simultaneous treatment of all wells, eliminating the need for multiple incubation steps or manual transfers. Specific sonication protocols can be saved and easily repeated, ensuring consistent and reproducible results.

✅ No Sample Loss: Sample recovery is often challenging with bead mills, as sample loss can occur during bead transfer. The UIP550MTP sonicator offers superior sample recovery and handling by eliminating the need for beads, reducing the complexity of separation steps and minimizing the risk of sample loss or contamination.

✅ Use Different Sample Vessels: The versatility of the UIP550MTP sonicator is another major advantage. It accommodates various plate formats and offers flexible sonication parameters, making it suitable for a wide range of sample types and applications. In addition to multiwell plates, it can be used for small vials, petri dishes, and other containers, for processes such as cell lysis, DNA fragmentation, emulsification, and degassing.

✅ Automation: Finally, the UIP550MTP sonicator integrates seamlessly with automated systems, allowing for smooth incorporation into auto-sampler lines. This compatibility ensures standardized, reproducible sample preparation, boosting efficiency and productivity in high-throughput environments.

Applications of the UIP550MTP High-Throughput Ultrasonicator

The UIP550MTP ultrasonicator fulfills numerous applications based on the type of sample. The following overview introduces you to the capabilities of the Hielscher UIP550MTP sonicator for sample preparation in biology, life science, genomics, proteomics and biomarker diagnostics.

Präzis Temperaturkontroll Wärend Microtiter Plate Sonication

De UIP550MTP ass en effektive 550-Watt Ultrasonikator deen Ultraschallwellen a Vibrationen duerch d'Mauere vun enger Mikroplatt iwwerdroe léisst, wat d'Proben indirekt beaflosst. Dëse Prozess erzeugt Kavitation an Scherrkräfte am Medium. Wéi aner mechanesch Zellstéierungsmethoden erzeugt d'Sonikatioun Hëtzt. Am Géigesaz zu anere Techniken bitt de UIP550MTP awer fortgeschratt Temperaturiwwerwaachung an erlaabt de Benotzer Temperaturgrenzen ze setzen fir d'thermesch Degradatioun vu biologeschen Proben ze verhënneren.
De UIP550MTP ass mat intelligenter Software ausgestatt, déi einfach iwwer en digitalen Touchscreen zougänglech ass. Dës Interface erlaabt Iech Temperaturgrenzen virzestellen an déi total Energieinput fir Är Probenveraarbechtung ze programméieren.

Iwwerwaachung vun der Probentemperatur: The UIP550MTP features an intelligent software system and a pluggable temperature sensor. By connecting the sensor to the UIP550MTP and placing the sensor tip into one of the microtiter wells, you can specify a temperature range for your sonication process using the digital touchscreen menu. The device will automatically stop when the maximum temperature is reached and pause until the sample cools down to the lower end of the specified temperature range. At that point, sonication will resume automatically. This feature helps prevent heat-induced sample degradation.

To further delay reaching the critical temperature limit, you can pre-cool the 96-well plate, microtiter plate, or ELISA plate and its samples.

Multi-Well Plate Sonicator UIP550MTP for High-Throughput Sample Prep

Customers around the world rely on the Hielscher UIP550MTP for efficient, reliable, and reproducible sample preparation in multi-well plates. This device simplifies daily tasks in biological, biochemical, life science, medical, and clinical laboratories. With its intelligent software and advanced temperature control, the UIP550MTP ensures precise temperature management, preventing heat-induced sample degradation. Ultrasonic sample preparation with the UIP550MTP consistently delivers dependable and reproducible results.

 
Looking for an ultrasonic system to process larger volumes? D'Tabell hei drënner gëtt Iech eng Indikatioun vun der ongeféier Veraarbechtungskapazitéit vun Hielscher Sonikatoren:
The table below lists our ultrasoniators from compact hand-held homogenizers and high-throughput / MultiSample sonicators to industrial ultrasonic processors for commercial liquid processing:
 

Literatur / Referenzen