Hielscher News
Hielscher News highlights the latest research, innovations, and applications in ultrasonic processing. From extraction and formulation to particle size reduction and cell disruption, our news articles provide concise insights into current scientific findings, industrial trends, and real-world use cases. Stay updated with expert analyses and practical information on how ultrasonic technology drives efficiency and performance across industries.
Ultrazvuk unapređuje materijale za promjenu faze za skladištenje energije
, Kathrin HielscherResearchers are increasingly using high-power ultrasonic processing (sonication) to improve the performance of phase-change materials (PCMs) used in thermal energy storage. By generating intense cavitation and micro-mixing, ultrasound enables the production of stable PCM dispersions, nano-enhanced PCMs, and nanoencapsulated materials with superior heat transfer and long-term stability. Studies show that sonication produces more homogeneous mixtures and smaller particle aggregates compared to conventional mixing methods, leading to more reliable thermal behavior and improved energy storage performance.
Advanced ultrasonic processors, such as those developed by Hielscher Ultrasonics, provide precise control over cavitation intensity and processing parameters, making them powerful tools for PCM research and scalable industrial production. The technology is already being used to disperse nanoparticles, create paraffin wax emulsions, and fabricate micro- and nano-encapsulated PCMs, helping researchers develop next-generation materials for building climate control, renewable energy storage, electronics cooling, and battery thermal management.
Kada žice moraju biti savršeno čiste: ultrazvučno inline čišćenje kao visokotehnološko rješenje
, Kathrin HielscherWhen surface cleanliness becomes a decisive factor in modern wire and cable production, ultrasonic inline cleaning offers a powerful solution. Even microscopic residues such as drawing oils, abrasion particles, or oxide layers can compromise downstream processes like electroplating, coating, welding, or soldering. Ultrasonically assisted systems remove these contaminants efficiently through acoustic cavitation – contact-free, reproducible, and fully integrated into high-speed production lines. Modular solutions such as the Hielscher USCM700 demonstrate how advanced filtration, scalable ultrasonic power, and compact inline design can enhance process stability, reduce chemical consumption, and ensure consistently high surface quality in demanding industrial applications.
https://www.hielscher.com/when-wires-must-be-perfectly-clean-ultrasonic-inline-cleaning-as-high-tech-solution.htm
Otpad od plastike i gume za jači i dugotrajniji asfalt
, Kathrin HielscherHigh-intensity ultrasonic mixing is emerging as a breakthrough method for turning waste plastic and crumb rubber into high-performance asphalt. Studies show recycled polymers like HDPE, LDPE, and PET can improve rutting resistance, moisture stability, and durability – but only when they are uniformly dispersed in bitumen. Hielscher Ultrasonics enables this with industrial-grade sonicators and a linearly scalable processing approach, allowing asphalt producers to move from lab trials to continuous inline production without changing the core mixing technology. This ultrasonic binder modification method supports stronger roads while helping reduce plastic pollution at scale.
https://www.hielscher.com/waste-plastic-and-rubber-for-stronger-longer-lasting-asphalt.htm
Liposomalni semaglutid bi mogao biti sljedeći veliki iskorak u isporuci GLP-1 lijekova
, Kathrin HielscherSemaglutide and other GLP-1 peptides are among the most important modern therapeutics, but formulation scientists still face a fundamental barrier: peptide drugs are difficult to protect and deliver, especially by the oral route. Even approved oral semaglutide products show bioavailability below 1%, requiring high doses and complex formulation strategies.
A growing technical focus in pharmaceutical development is liposomal encapsulation combined with high-intensity ultrasonic processing. Liposomes can stabilize GLP-1 peptides and enable nano-scale carrier systems, while ultrasound provides reproducible nano-sizing and a scalable manufacturing pathway. Semaglutide is particularly compatible with lipid carriers because studies indicate it can associate with vesicle membranes via its lipid tail, supporting efficient loading into lipid bilayers.
Sonikacija omogućava novi nivo kontrole u samoorganizaciji celuloznih nanokristala
, Kathrin HielscherSonication holda the key to unlocking more reliable, scalable production of cellulose nanocrystal (CNC) materials. A new study reveals that sonication doesn’t just break up CNC clusters – it actively reshapes how these sustainable nanomaterials self-assemble into cholesteric liquid crystal structures responsible for brilliant structural color. By observing CNC ordering inside tiny evaporating droplets, researchers found that ultrasound can delay gelation, shift kinetic arrest, and tune the helical pitch evolution with remarkable precision. The findings highlight sonication as an industrially relevant processing lever for programming reproducible CNC-based photonic coatings and advanced bio-based materials at scale.
https://www.hielscher.com/sonication-enables-a-new-level-of-control-in-cellulose-nanocrystal-self-assembly.htm
Sono-elektrokemijska sinteza poboljšava efikasnost u hemijskoj proizvodnji
, Kathrin HielscherResearchers are increasingly turning to sono-electrochemical synthesis to improve the efficiency of chemical manufacturing. By combining power ultrasound with electrochemistry, scientists report enhanced mass transfer, higher current efficiency, and reduced energy losses. Industrial-grade ultrasonic electrodes from Hielscher Ultrasonics are enabling scalable implementations of this technology, making ultrasound-assisted electrosynthesis a practical option for modern, energy-efficient chemical production.
https://www.hielscher.com/sono-electrochemistry-improves-chemical-manufacturing.htm
Kako ultrazvučna disperzija poboljšava performanse mokrog kraja i smanjuje troškove
, Kathrin HielscherPapermakers are discovering that better chemistry doesn’t always mean more chemistry. A growing number of mills are turning to ultrasonic dispersion to improve how wet end additives are mixed and activated before they ever reach the stock. By using high-power ultrasound to break up agglomerates and homogenize chemical streams in-line, mills can improve retention, formation, and process stability while reducing chemical consumption and energy use. With linear scalability and industrial-grade sonicator systems from Hielscher Ultrasonics, ultrasonic dispersion is moving from the lab into full-scale paper production as a practical, cost-effective wet end upgrade.
https://www.hielscher.com/how-ultrasonic-dispersion-improves-wet-end-performance-and-cuts-costs.htm
Kako sonikacija može pojačati lizozim za lizu bakterijskih ćelija
, Kathrin HielscherSonication boosts lysozyme efficiency in bacterial cell lysis: Researchers find a growing body of research shows that combining lysozyme with ultrasonic sonication dramatically improves bacterial cell lysis in biotechnology and protein production workflows. While lysozyme alone often struggles with dense or over-expressing bacterial cultures, sonication enhances enzyme effectiveness by weakening cell walls through cavitation-driven mechanical forces. The result is faster processing, more complete cell disruption, and higher protein yields. Laboratories increasingly use Hielscher sonicators to precisely control ultrasonic energy, reduce processing time, and achieve reproducible results across research and industrial-scale applications.
https://www.hielscher.com/sonication-supercharges-lysozyme-for-bacterial-cells.htm
Proizvodnja lijekova: Sonication oblikuje budućnost biogenih lijekova
, Kathrin HielscherThis news article presents how sonication is transforming biogenic drug manufacturing: Ultrasonic processing is rapidly emerging as a key technology in the manufacturing of biogenic drugs, enabling greener, more efficient production of bioactive compounds and nanomedicines. New research demonstrates that ultrasound-assisted synthesis, using plant extracts such as broccoli, can produce highly stable, biologically active gold nanoparticles with antioxidant, wound-healing, and selective anticancer properties. High-performance probe-type sonicators, including industrial systems from Hielscher Ultrasonics, play a critical role by enhancing extraction efficiency, accelerating green nanoparticle synthesis, and ensuring precise process control. As demand grows for sustainable pharmaceutical manufacturing, sonication is positioning itself as a scalable, GMP-compatible platform for next-generation biogenic drugs.
https://www.hielscher.com/sonication-shapes-biogenic-medicines.htm
Microplate Sonicator potvrđen u recenziranoj proteomskoj studiji
, Kathrin HielscherA peer-reviewed study published in Proteomics (2024) confirms that the UIP400MTP ultrasonic microplate sonicator delivers reliable, high-quality protein extraction for advanced shotgun proteomics and terminomics workflows. In a direct comparison with bead beating and bath sonication, the UIP400MTP achieved comparable proteome coverage and high quantitative reproducibility without inducing artificial proteolysis. The results validate ultrasonic microplate sonication as a robust, high-throughput solution for standardized mass spectrometry sample preparation.
https://www.hielscher.com/uip400mtp-sonicator-validated-in-peer-reviewed-study.htm
Nova Sonication tehnologija pojednostavljuje pripremu uzorka u standardnim Falcon cijevima od 50 mL
, Kathrin HielscherA new VialTweeter-spec sonicator designed for single 50 mL Falcon tubes is helping laboratories streamline sample preparation while reducing contamination risks. By enabling high-intensity, non-contact ultrasonic processing in closed tubes, the system allows researchers to perform ultrasonic lysis and move directly to centrifugation and downstream steps without transferring samples. The approach improves workflow efficiency, reproducibility, and safety-benefits that are especially relevant for applications such as extracellular vesicle research, proteomics, and other sensitive analytical procedures.
https://www.hielscher.com/new-sonication-technology-streamlines-sample-prep-in-standard-50-ml-falcon-tubes.htm
Novi mikropločni sonikatori za razbijanje tvrdokornih biofilmova
, Kathrin HielscherScientists are increasingly turning to high-performance multi-well plate sonicators such as the Hielscher UIP400MTP to tackle one of microbiology’s toughest challenges: dislodging stubborn biofilms from MBEC™ plates for accurate antibiotic resistance testing. New research shows that biofilm-embedded bacteria can become up to 32-fold more drug-resistant, making reliable ultrasonic disruption essential for clinical and laboratory diagnostics. The UIP400MTP’s uniform cavitation, programmable settings, and high-power 400-watt output deliver consistent, reproducible biofilm removal – helping researchers better assess real-world antimicrobial effectiveness as global antibiotic resistance continues to rise.
https://www.hielscher.com/research-highlights-plate-sonicators-for-breaking-biofilms.htm