Hielscher News
Hielscher News highlights the latest research, innovations, and applications in ultrasonic processing. From extraction and formulation to particle size reduction and cell disruption, our news articles provide concise insights into current scientific findings, industrial trends, and real-world use cases. Stay updated with expert analyses and practical information on how ultrasonic technology drives efficiency and performance across industries.
Ultrazvuk unapređuje materijale za promjenu faze za skladištenje energije
, Kathrin HielscherIstraživači sve više koriste visokoučinsku ultrazvučnu obradu (sonikaciju) kako bi poboljšali učinak materijala koji mijenjaju fazu (PCM) korištenih u skladištenju termalne energije. Generiranjem intenzivne kavitacije i mikro-miješanja, ultrazvuk omogućava proizvodnju stabilnih PCM disperzija, nano-poboljšanih PCM-a i nanoenkapsuliranih materijala sa superiornim prijenosom toplote i dugoročnom stabilnošću. Studije pokazuju da sonikacija proizvodi homogenije smjese i manje agregate čestica u poređenju sa konvencionalnim metodama miješanja, što vodi ka pouzdanijem termalnom ponašanju i poboljšanoj učinkovitosti skladištenja energije.
Napredni ultrazvučni procesori, poput onih koje je razvio Hielscher Ultrasonics, omogućavaju preciznu kontrolu nad intenzitetom kavitacije i parametrima obrade, čineći ih moćnim alatima za PCM istraživanje i skalabilnu industrijsku proizvodnju. Tehnologija se već koristi za raspršivanje nanočestica, stvaranje parafinskih voskastih emulzija i izradu mikro- i nano-enkapsuliranih PCM-ova, pomažući istraživačima da razviju materijale nove generacije za kontrolu klime u zgradama, skladištenje obnovljive energije, hlađenje elektronike i termalno upravljanje baterijama.
Otpad od plastike i gume za jači i dugotrajniji asfalt
, Kathrin HielscherHigh-intensity ultrasonic mixing is emerging as a breakthrough method for turning waste plastic and crumb rubber into high-performance asphalt. Studies show recycled polymers like HDPE, LDPE, and PET can improve rutting resistance, moisture stability, and durability – but only when they are uniformly dispersed in bitumen. Hielscher Ultrasonics enables this with industrial-grade sonicators and a linearly scalable processing approach, allowing asphalt producers to move from lab trials to continuous inline production without changing the core mixing technology. This ultrasonic binder modification method supports stronger roads while helping reduce plastic pollution at scale.
https://www.hielscher.com/waste-plastic-and-rubber-for-stronger-longer-lasting-asphalt.htm
Liposomalni semaglutid bi mogao biti sljedeći veliki iskorak u isporuci GLP-1 lijekova
, Kathrin HielscherSemaglutid i drugi GLP-1 peptidi spadaju među najvažnije moderne terapije, ali naučnici koji razvijaju formulacije i dalje se suočavaju s osnovnom preprekom: peptidni lijekovi su teški za zaštitu i isporuku, posebno putem oralnog puta. Čak i odobreni oralni proizvodi semaglutida pokazuju bioraspoloživost ispod 1%, što zahtijeva visoke doze i složene strategije formulacije.
A growing technical focus in pharmaceutical development is liposomal encapsulation combined with high-intensity ultrasonic processing. Liposomes can stabilize GLP-1 peptides and enable nano-scale carrier systems, while ultrasound provides reproducible nano-sizing and a scalable manufacturing pathway. Semaglutide is particularly compatible with lipid carriers because studies indicate it can associate with vesicle membranes via its lipid tail, supporting efficient loading into lipid bilayers.
Sonikacija omogućava novi nivo kontrole u samoorganizaciji celuloznih nanokristala
, Kathrin HielscherSonication holda the key to unlocking more reliable, scalable production of cellulose nanocrystal (CNC) materials. A new study reveals that sonication doesn’t just break up CNC clusters – it actively reshapes how these sustainable nanomaterials self-assemble into cholesteric liquid crystal structures responsible for brilliant structural color. By observing CNC ordering inside tiny evaporating droplets, researchers found that ultrasound can delay gelation, shift kinetic arrest, and tune the helical pitch evolution with remarkable precision. The findings highlight sonication as an industrially relevant processing lever for programming reproducible CNC-based photonic coatings and advanced bio-based materials at scale.
https://www.hielscher.com/sonication-enables-a-new-level-of-control-in-cellulose-nanocrystal-self-assembly.htm
Sono-elektrokemijska sinteza poboljšava efikasnost u hemijskoj proizvodnji
, Kathrin HielscherResearchers are increasingly turning to sono-electrochemical synthesis to improve the efficiency of chemical manufacturing. By combining power ultrasound with electrochemistry, scientists report enhanced mass transfer, higher current efficiency, and reduced energy losses. Industrial-grade ultrasonic electrodes from Hielscher Ultrasonics are enabling scalable implementations of this technology, making ultrasound-assisted electrosynthesis a practical option for modern, energy-efficient chemical production.
https://www.hielscher.com/sono-electrochemistry-improves-chemical-manufacturing.htm
Kako ultrazvučna disperzija poboljšava performanse mokrog kraja i smanjuje troškove
, Kathrin HielscherProizvođači papira otkrivaju da bolja hemija ne znači uvijek više hemije. Sve veći broj tvornica okreće se ultrazvučnoj disperziji kako bi poboljšali način na koji se dodaci za mokri kraj miješaju i aktiviraju prije nego što uopšte stignu do kaše. Korištenjem visokosnažnog ultrazvuka za razbijanje aglomerata i homogenizaciju hemijskih tokova u liniji, tvornice mogu poboljšati zadržavanje, formiranje i stabilnost procesa, dok smanjuju potrošnju hemikalija i energije. Sa linearnom skalabilnošću i industrijskim sonikatorima tvrtke Hielscher Ultrasonics, ultrazvučna disperzija prelazi iz laboratorija u proizvodnju papira u punoj skali kao praktično i isplativo unapređenje mokrog kraja.
https://www.hielscher.com/how-ultrasonic-dispersion-improves-wet-end-performance-and-cuts-costs.htm
Kako sonikacija može pojačati lizozim za lizu bakterijskih ćelija
, Kathrin HielscherSonication boosts lysozyme efficiency in bacterial cell lysis: Researchers find a growing body of research shows that combining lysozyme with ultrasonic sonication dramatically improves bacterial cell lysis in biotechnology and protein production workflows. While lysozyme alone often struggles with dense or over-expressing bacterial cultures, sonication enhances enzyme effectiveness by weakening cell walls through cavitation-driven mechanical forces. The result is faster processing, more complete cell disruption, and higher protein yields. Laboratories increasingly use Hielscher sonicators to precisely control ultrasonic energy, reduce processing time, and achieve reproducible results across research and industrial-scale applications.
https://www.hielscher.com/sonication-supercharges-lysozyme-for-bacterial-cells.htm
Proizvodnja lijekova: Sonication oblikuje budućnost biogenih lijekova
, Kathrin HielscherThis news article presents how sonication is transforming biogenic drug manufacturing: Ultrasonic processing is rapidly emerging as a key technology in the manufacturing of biogenic drugs, enabling greener, more efficient production of bioactive compounds and nanomedicines. New research demonstrates that ultrasound-assisted synthesis, using plant extracts such as broccoli, can produce highly stable, biologically active gold nanoparticles with antioxidant, wound-healing, and selective anticancer properties. High-performance probe-type sonicators, including industrial systems from Hielscher Ultrasonics, play a critical role by enhancing extraction efficiency, accelerating green nanoparticle synthesis, and ensuring precise process control. As demand grows for sustainable pharmaceutical manufacturing, sonication is positioning itself as a scalable, GMP-compatible platform for next-generation biogenic drugs.
https://www.hielscher.com/sonication-shapes-biogenic-medicines.htm
Microplate Sonicator potvrđen u recenziranoj proteomskoj studiji
, Kathrin HielscherA peer-reviewed study published in Proteomics (2024) confirms that the UIP400MTP ultrasonic microplate sonicator delivers reliable, high-quality protein extraction for advanced shotgun proteomics and terminomics workflows. In a direct comparison with bead beating and bath sonication, the UIP400MTP achieved comparable proteome coverage and high quantitative reproducibility without inducing artificial proteolysis. The results validate ultrasonic microplate sonication as a robust, high-throughput solution for standardized mass spectrometry sample preparation.
https://www.hielscher.com/uip400mtp-sonicator-validated-in-peer-reviewed-study.htm
Nova Sonication tehnologija pojednostavljuje pripremu uzorka u standardnim Falcon cijevima od 50 mL
, Kathrin HielscherA new VialTweeter-spec sonicator designed for single 50 mL Falcon tubes is helping laboratories streamline sample preparation while reducing contamination risks. By enabling high-intensity, non-contact ultrasonic processing in closed tubes, the system allows researchers to perform ultrasonic lysis and move directly to centrifugation and downstream steps without transferring samples. The approach improves workflow efficiency, reproducibility, and safety-benefits that are especially relevant for applications such as extracellular vesicle research, proteomics, and other sensitive analytical procedures.
https://www.hielscher.com/new-sonication-technology-streamlines-sample-prep-in-standard-50-ml-falcon-tubes.htm
Novi mikropločni sonikatori za razbijanje tvrdokornih biofilmova
, Kathrin HielscherScientists are increasingly turning to high-performance multi-well plate sonicators such as the Hielscher UIP400MTP to tackle one of microbiology’s toughest challenges: dislodging stubborn biofilms from MBEC™ plates for accurate antibiotic resistance testing. New research shows that biofilm-embedded bacteria can become up to 32-fold more drug-resistant, making reliable ultrasonic disruption essential for clinical and laboratory diagnostics. The UIP400MTP’s uniform cavitation, programmable settings, and high-power 400-watt output deliver consistent, reproducible biofilm removal – helping researchers better assess real-world antimicrobial effectiveness as global antibiotic resistance continues to rise.
https://www.hielscher.com/research-highlights-plate-sonicators-for-breaking-biofilms.htm