I-Hielscher Ultrasound Technology

Ukukhipha i-Ultrasonic Ukusebenzisa i-Hemp njengempahla ebonakalayo

  • Ukuze isitshalo se-cannabis sativa, izinhlobo ezimbili zingahlukaniswa: i-marijuana ne-hemp.
  • I-Ultrasonic iyaziwa ngokuthi iyindlela ephakeme yokuhlukanisa i-cannabinoids kokubili, i-mariju ne-hemp.

 

Hemp vs Marijuana

I-Cannabis sativa isitshaloI-Cannabis ngumndeni wezitshalo ezingahle zihlukaniswe C. Indica futhi C. Sativa. Ukuhlamba kanye nensangu yizinhlobo ze-Cannabis Sativa.
Uma kuqhathaniswa neHemp vs Marijuana, kukhona umehluko omkhulu; ngenkathi i-Hemp iqukethe ukuhlushwa okuphansi kakhulu kwe-THC (0.3% noma ngaphansi), i-Marijuana iningi ku-THC ngokugxila phakathi kuka-15% no-40%.
Ngakho-ke, kuze kube yilapho nje i-hemp ikhule ngokuyinhloko ngenhloso yezimboni. Namuhla, i-hemp ibaluleka ekuvuneni kwe-CBD, futhi. I-CBD iyi-non-psychoactive cannabinoid enezinto zokulwa nokuvuvukala, ze-anxiolytic. I-Marijuana ikhule ngokuyinhloko ngenxa yezinto zayo ze-THC, esetshenziselwa ukuzithokozisa kanye nokwelapha.

Hemp oyela kanye ne-CBD, i-cannabinoid eyinhloko etholakalayo e-hemp, yizinto ezithembisayo ezilawulwayo ukuze zisize ngezimo zezokwelapha ezifana nokukhathazeka, ukuvuvukala okungapheli, izifo ezizimele, ubuhlungu, izinhlungu zomzimba kanye ne-migraine, ukuphazamiseka kwamathumbu, ngaphandle kwamanye.

Ukukhishwa kwe-Ultrasonic ye-Cannabinoids

Ubuchwepheshe be-ultrasonic ubuchwepheshe bukhulu kakhulu ukukhulula ama-active acids (okungukuthi i-cannabinoids (I-CBD, I-THC, i-CBG), Amafutha abalulekile, Terpenes njll) kusuka emthini wezitshalo ezifana namahlumela, amaqabunga, neziqu.
Isizinda se-ultrasonic siphumelela ngaphandle kwamasu amasu avamile okukhipha izinkathazo eziningana izinzuzo ezihlukahlukene:
Isizinda se-Ultrasonically-basizwa (UAE) saziwa kakhulu njengenqubo yokwandisa inqubo, eyenza ngcono ukudluliselwa kwamandla nokukhishwa Izithelo Eziphakeme yamakhemikhali e-bioactive njenge-cannabinoids, i-terpenes njll.
I-Ultrasonication iveza izitshalo eziphezulu ngoba isizinda se-ultrasonic asidingi ukusetshenziswa kwamakhemikhali anonya, ayenobuthi ukuze akhululwe ama-cannabinoids. Isizinda se-ultrasonic singasetshenziswa ngamanzi, ingxube yamanzi, utshwala noma amafutha (umnqumo, ukhukhunathi) njenge Izixazululo, Ngokwesibonelo. Lokhu kwenza isizinda se-ultrasonically-basizwa (UAE) kakhulu umlingani wezemvelo.
Izimo zesikhumba esincane somphumela we-UAE ku-extract, enikeza okufanayo, kodwa izakhiwo eziqinile zomsindo (isib. I-hemp, i-marijuana) - enikeza imiphumela ephakeme yempilo, ukunambitheka, nokuphunga.
I-extractors ka-Hielscher ultrasonic ingalawulwa ngokuqondile. Ngokulawula ngokugcwele emigomeni yenqubo njengobuningi nokushisa, ikhwalithi ephakeme kakhulu yokukhipha ingatholakala. Njengoba sonication kuyinto a non-thermal indlela yokucubungula, ukuchithwa okushisayo kwezinsimbi ezibhekene nokushisa kugwenywe. Ukushisa kwamazinga okushisa phakathi kuka-0-60 ° C kulungele ukukhishwa okuphakeme.
Enye inzuzo ye-UAE yiyona inqubo esheshayo: Inqubo yonke yokukhipha ithatha amaminithi ambalwa ukukhulula ama-cannabinoid kusuka kumaseli esitshalo, kanti amanye amasu okukhishwa adinga amahora noma ngisho nezinsuku zokucubungula isikhathi.
Kokubili, izindleko zokutshala izimali kanye nokusebenza akuzona eziqhathaniswa nokuqhathaniswa namanye ama-extractors, isib. CO supercritical2 ama-extractors. Izinhlelo ze-ultrasonic izizinda zine I-RoI esheshayo kakhulu.

U-UP400St we-Hielscher ungumbonisi onamandla we-ultrasonic (Chofoza ukuze ukhulise!)

UP400St ukukhishwa kwama-cannabinoid kusuka ku-hemp

Isicelo solwazi




Qaphela kwethu Inqubomgomo yobumfihlo.


Izinzuzo ze-Ultrasonic Extraction

  • Izitshalo eziphezulu zekhwalithi
  • isizinda esiphelele ngokwengeziwe
  • izinga eliphezulu lokukhipha
  • Ukukhishwa kwe-spectrum ephelele
  • Ukusetshenziswa kwama-solvents ahlukahlukene
  • non-toxic
  • Indlela engeyona eyashisayo (ebandayo)
  • Inqubo yokukhipha ngokushesha
  • Kuphephile futhi kulula ukuyisebenzisa
  • ukusabalalisa okulinganayo

Ukusebenza okuphezulu kwe-Ultrasonic Extractors

Hielscher Ultrasonics’ okunikezwayo encane, ubukhulu obuphakathi futhi Izimboni amaprosesa e-ultrasonic, angasetshenziswa 24/7. Kuncike ekutheni ivolumu yakho nenqubo yokusebenza, sikwazi ukukunikeza uhlelo lwe-ultrasonic yezizinda ezihambisana nezidingo zakho. Ungakhetha phakathi kwe-batch ne-extraction. Ngokukhamba kwesikhathi ukukhishwa kwamandla okusebenza okukhudlwana kungenziwa kalula kusukela izinqubo ze-ultrasonic zingahle zenziwe ngokulinganayo.
Izinhlelo ze-pilot kanye nezimboni ze-Hielscher zingakwazi ukuletha ama-amplitudes aphakeme kakhulu – okuvumela ukuqhuba amam amplitudes angafika ku-200μm athembeke futhi aqhubeke nokusebenza ku-24/7. Nge-amplitudes ephakeme nakakhulu, i-sonotrode e-ultrasonic eyenziwe ngezifiso iyatholakala. Ukuqina kwemishini ye-ultrasonic ye-Hielscher kuvumela imisebenzi enesimweni esindayo nasezindaweni ezinzima.
Njengomkhiqizi wesikhathi eside eside we-ultrasonic extractors, u-Hielscher ungumlingani wakho onokwethenjelwa wesakhiwo esiyinkimbinkimbi. Thina thintana futhi usize amakhasimende ethu ngolwazi lwethu futhi sibaqondise kusuka ekuhloleni okusemandleni ukufakwa kwezimboni.
Xhumana nathi manje! Siyajabula ukuxoxa ngezidingo zakho zokukhishwa nawe!

Xhumana nathi! / Cela Us!

Cela ulwazi oluthe xaxa

Sicela usebenzise ifomu elingezansi, uma ufisa ukucela ulwazi oluthe xaxa mayelana ne-homogenization yama-ultrasonic. Sizojabula ukukunikeza uhlelo lwe-ultrasonic ukuhlangabezana nezidingo zakho.









Sicela uqaphele wethu Inqubomgomo yobumfihlo.


UIP4000hdT (4kW) iprosesa ye-ultrasonic ye-extraction ye-cannabinoids (i-CBD, i-THC) kanye ne-terpenes kusuka ku-hemp kanye nensangu.

Ukufakwa kwama-Hielscher I-UIP4000hdT, udoti we-4kW ultrasonic, we-industrial extraction.

Izincwadi / Izinkomba

  • U-Uma Altaf, A Rouf, uVarsha Kanojia, uQudsiya Ayaz, u-Imtiyaz Zargar (2018): Ukwelashwa kwe-ultrasound: I-innovative technique yokulungisa ukudla. I-Pharma Innovation Journal 2018; 7 (2): 234-241.
  • U-Renata Vardanega, u-Diego T. Santos, uMnuz Angela A. Meireles (2014): Ukuqiniswa kwezinto eziphilayo eziyinkimbinkimbi ezivela kwezitshalo zokwelapha usebenzisa irradiation ye-ultrasonic. Umfundisi we-Pharmacogn 2014 Jul-Dec; 8 (16): 88-95.
  • U-Charu Agarwal, uKatalin Máthé, uTámas Hofmann, Levente Csóka (2018): Ukwenziwa kwe-Ultrasound-Ukusizwa kwama-Cannabinoids kusuka ku-Cannabis Sativa L. Ukulungiswa yi-Response Surface Methodology. Journal of Food Science, February 2018.


Amaqiniso Okufanele Ukwazi

Isizinda se-Ultrasonic siphumelele kumasu ephumelela kakhulu nangomsebenzisi-friendly uma kuziwa esikhwameni samakhemikhali e-bioactive kusuka ku-botanicals. Isibonelo esivelele kunazo zonke sokufakelwa okuphumelelayo kungase kube ukuhlukaniswa kwe-CBD nezinye izidakamizwa ezivela ku-cannabis.

Ultrasonic vs. Izindlela zokwelapha ezivamile

Ukungena ku-ethanol kuyindlela elula, kodwa isikhathi esiningi kakhulu, inqubo yesikhundla sinciphile futhi izindleko zokuxazulula kanye nezamandla ziphezulu. I-solvent ehlala njalo emkhiqizo wokugcina iphazamisa umgomo wokukhiqiza ukukhishwa okusezingeni eliphezulu.
Ukusetshenziswa ngokusebenzisa uhlelo oluvaliwe lwe-hydrocarbon kudinga ukusetshenziswa kwamafutha, ukuze izinto ezibangelwa umdlavuza ezifana ne-benzene zingatholakala kumkhiqizo wokugcina.
I-CO eqoshiwe2 izinhlelo zokufakelwa ziphezulu ezindleko zokutshala izimali kanye nokusetshenziswa kwamandla. I-CO eqoshiwe2 I-extractors idinga abasebenzi abaqeqeshwe kahle ukuba basebenze kusukela CO yokucindezela phezulu2 izinhlelo ziyingozi ukusebenzisa. Uma i-CO2 ukuvuza kungabangela ukufa kwabasebenzi okwamanje.
Isizinda samanzi esiyingqayizivele kungenye indlela ephathelene nemvelo-friendly, okuyinto ephuthumayo futhi ikhishwa kuphela ingxenyana encane yezinhlanganisela eziphilayo.

Isizinda se-Ultrasonic

Isizinda se-ultrasonic yindlela yokuqinisa yesikhumba engasetshenziswa ngokuhlanganiswa nayo amanzi (okungenasombululo) kanye ne Izixazululo ezifana ne-ethanol, i-ethanol-water, i-glycerin, i-methanol, i-vegetable oils noma ezinye izixazululo ozikhethelayo. Isizinda se-Ultrasonic sithuthukisa ukudluliswa kwamandla ukuze ukhiqize isivuno sika 95-99% ingatholakala. I-Sonication ingenziwa kalula futhi ikhiqize izitshalo eziphezulu.
Udoti omncane we-ultrasonic onjalo I-UIP400St (400W) iyakwazi ukucubungula i-batch efika ku-10L phakathi no-5-15maminithi (kuye ngokuthi imingcele yezinqubo ezifana nokusetshenziswa okuluhlaza (okusha noma omisiwe; amaqabunga, amaqabunga, iziqu), i-solvent, izinga lokushisa). Umklomelo we-2kW onamandla we-ultrasonic I-UIP2000hdT ingaqhutshwa njengesistimu ehleliwe. Kumodi yokugeleza, i I-UIP2000hdT kalula ihamba 200 kuya ku-800L / hr (futhi kuye ngokuthi inqubo yezinqubo).
Izindleko zokutshala izimali zeproshini ye-ultrasonic ziphansi uma kuqhathaniswa ne-CO2 umcwaningi. Futhi izindleko zamandla zokusebenza azizinaki. I-ultrasonic extractors iphephile kakhulu ukusebenza, kulula ukuhlanza futhi idinga ukugcinwa okuphansi kakhulu.

Hielscher Ultrasonics 'extractors outperform ezejwayelekile izindlela zokukhipha izizinda ngekhwalithi ephezulu kanye nokukhishwa okuphelele okwengeziwe.

Ukuqhathanisa phakathi kwe-ultrasonic (eluhlaza) nokulawula (okwesibhakabhaka) isizinda. Umthombo: Agarwal et al. 2018

i-cannabis

Izakhi eziphilayo ze-cannabis (kokubili, isitshalo se-hemp nesangu) ziye zathola ukunakwa okuningi esikhathini esidlule esiseduze. Ikakhulukazi ye-Cannabidiol ye-cannabidiol (i-CBD) izinzuzo eziningi zezempilo ziboniswe, ezifinyelela emithini yokulwa nomdlavuza kanye nezakhiwo eziphikisayo ukuze kutholakale ubuhlungu-ukukhulula nemiphumela ephikisayo. Ngaphandle kwe-cannabidiol, isitshalo se-cannabis siqukethe izinhlobo eziningi ze-cannabinoids njenge-THC (tetrahydrocannabinol), i-cannabinol (i-CBN), i-cannabigerol (i-CBG), i-cannabichromene (i-CBC), ne-cannabinodiol (i-CBND). Ama-cannabinoids abonise amandla amakhulu okuhlinzeka futhi asezinhlobonhlobo zocwaningo zocwaningo eziningi.
Ukusebenzisana kwama-cannabinoids ahlukahlukene nezinye izinto ezixubile njenge-terpenes, polyphenols, flavonoids, kanye ne-alkaloid kubukeka sengathi kuholela ezinzuzweni ezingcono kakhulu zezempilo. I-interplay yama-terpenes ahlukene, ama-cannabinoids ahlukile nezinye izakhi zezitshalo kuthiwa “umphumela we-entourage”. Ngenxa yempembelelo ye-entourage, ukukhishwa kwe-spectrum egcwele, okungatholakala ngokuphumelelayo nge-ultrasonically-assisted extraction (UAE), yaziwa ngemiphumela yokwelapha ehlukile.

I-Cannabis Terpenes

I-terpenoids yizingxenye ezibalulekile zamafutha, ezitholakala kubhodals. Isitshalo se-cannabis sicebile kakhulu Terpenes. E-cannabis, i-terpenes yenziwa ezinhlotsheni zesitshalo. I-trichomes yi-crystals ekhanyayo, enamathelayo ehambisana namagqabi namafihlethi. Lezi zinhlanzi ziwumthombo wokuzivikela wemvelo wesitshalo se-cannabis, esivikela isitshalo ngokumelene nezinambuzane nezilwane. Ngenxa iphunga elimnandi, i-terpenes yenza njengento ephikisayo. Kithina bantu, isici esivelele kakhulu se-cannabis terpenes yiphunga layo. Lezi zitshalo zifaka isandla ezintweni eziningi zempilo zesitshalo se-cannabis (i-hemp ne-marijuana). I-terpenes embalwa efana ne-THC isebenza njengemithi engasebenzi futhi ibangele “phezulu” umphumela.
Ngaphandle kwephunga elimnandi nelithunga elimnandi, ama-molecule e-terpene anezinto ezinamandla ezitshalo ezithinta izidakamizwa ezihlukahlukene.
Kokubili inambuzane kanye ne-hemp ye-Cannabis Sativa ihlobo lunezibalo eziningi ze-terpenoids futhi liqukethe izinhlobo ezingaphezu kwezingu-100 zalezi zinto.
I-terpene ngayinye inezakhiwo ezihlukile ezisukela ekuvukeni kuya ekuphakamiseni. Isibonelo, i-nerolidol inemiphumela yokuvumelanisa nokulwa nokukhathazeka, i-linalool isiza ukuphatha izimpawu zokukhathazeka ne-arthritis, kanti i-myccene iyaziwa ukuthi idambisa izinhlungu ezingapheli. I-terpenes β-Myrcene,? -Pinene kanye ne-humulene kunciphisa ukuvuvukala futhi kube nemiphumela ye-analgesic.
I-terpenes ehlukahlukene iyingqayizivele e-cannabis, kodwa eziningi ze-terpenes ezitholakala ku-cannabis zikhona kwezinye izitshalo eziningana, futhi. I-caryophyllene itholakala isib egumbini elihlaza okwesibhakabhaka, Hops kanye ne-rosemary ne-oregano. I-Limonene yiyona terpene enkulu etholakala ezithelo zamawolintshi ezinjengolamula namawolintshi.

Umthelela we-Entourage

I-terpene ngayinye iyaziwa ngemiphumela ethize yokwelapha. Kodwa-ke, ama-terpenes nezinye izinhlanganisela ze-botanical ezifana ne-polyphenols ne-flavonoid ziyaziwa zibonisa imiphumela ehlukile yes synergetic, okuholela ekutheni kube ne-Symbiosis ethuthukisiwe phakathi kwe-cannabinoids. Lokhu kuhlangana kwezindlela ezixubile zezinto eziphilayo ezaziwa ngokuthi “umphumela we-entourage“.
Umthelela we-entourage wenza ama-terpenes aphinde atholakale kakhulu futhi atsize umzimba ukuthi uthathe ama-cannabinoids ngokuphumelelayo.

Izinhlobo ze-Bioactive Compounds

Inombolo, ukuhlushwa nokuhlukahluka kwamakhemikhali e-bioactive kubhekene nemithi yokwelapha ye-extract ye-botanical. Lezi zinhlanganisela ze-bioactive zihlanganiswa njenge-metabolites yesibili, engabambi ekukhuleni noma kwi-photosynthesis ezitshalweni. Noma kunjalo, zibalulekile ezitshalweni’ ukusinda nokuxhumana nemvelo yayo. Amakhemikhali e-botanical bioactive angafakwa kabanzi emaceleni amathathu ase-terpenes kanye ne-terpenoids, ama-alkaloids, nama-phenolic compounds. Ama-phenolic compounds yiqembu elalisakazwa kabanzi kunazo zonke ze-metabolites yesibili embusweni wezitshalo futhi ziyaziwa futhi zithandwa ngemiphumela yazo ye-antioxidative. Esinye isigaba esibalulekile samakhemikhali ama-phenolic esisisindo esincane esincane kakhulu yi-flavonoids, ekhombisa imiphumela enamandla kakhulu ye-antioxidative, futhi.
Ububanzi bezinhlanganisela ze-phenolic zihlanganisa i-phenolic acid njenge-benzoic ne-hydroxycinnamic acid, i-flavonoids njenge-flavones ne-flavonols, i-lignans, ne-stilbenes. Ukukhishwa kwe-spectrum ephelele (isb. Etholakalayo Isizinda se-ultrasonic kusuka ku-cannabis) ihlanganisa zonke lezi zakhi ezihlukahlukene ze-botanical, ezibonisa imiphumela yempilo ebanzi kakhulu.

I-Principle yokusebenza ye-Ultrasonic Extraction

Isizinda se-ultrasonic sisekelwe kuma-acoustic agesi (i-ultrasound) ehlanganiswe ibe yi-media ye-liquid. Amagagasi amakhulu e-ultrasound enza umjikelezo ophansi / ocindezelayo ophansi. Ngenxa yokungafani kwezingcindezi ngesikhathi kusakazwa amaza e-ultrasound nge-liquid, ama-bubble ama-cavitation ayenzeka. I-implosion yalezi zinhlayiya ze-cavitation iholela ezimweni ezinamandla-ezinomsoco.

Isizinda se-Ultrasonic samafutha abalulekile namakhemikhali asebenzayo avela kokuqukethwe kwe-botanical.

Isizinda se-ultrasonic samakhemikhali asebenzayo namafutha abalulekile kusekelwe esimisweni sokusebenza i-acoustic cavitation. Isibalo esingenhla sibonisa umphumela wokuwa kwe-cavitation bubble nokukhululwa kwamafutha abalulekile okuvela emthini wesitshalo
Umthombo: Altaf et al. 2018

Izimo eziseduze ne-imploding bubbles cavitation zingaba ngokweqile – kukhiqiza amazinga okushisa afinyelela ku-4500 ° C nezingcindezi ezifika ku-100 MPa. Ukwehlukahlukana okuphindayo nokuholela kokuphumula kuphumela emandleni aphezulu kakhulu e-shear nezidubedube endaweni eshisayo ye-cavitational. Ukuhlanganiswa kwalezi zinto zokuhlukaniswa kwengcindezi, umehluko wokushisa kanye nokugunda izinwele kugqugquzela ukuthunyelwa kweningi futhi ngaleyo ndlela izinqubo zokukhishwa. Ngamandla amakhulu we-ultrasonic cavitation, amaseli (isb. Zezitshalo, amagciwane, noma izicubu) ayaphazamiseka futhi izinto ezingaphakathi (ezinjengamafutha, i-lipid, amaprotheni, nezinto ezisebenzayo) zidedelwa ku-solvent ezungezile.
Ngakho-ke isizinda se-ultrasonic yindlela ekhethiwe yokuqinisa izinqubo zesikhumba.

I-ultrasonic / acoustic cavitation idala amabutho amakhulu kakhulu avula izindonga zeseli eziziwa ngokuthi i-lysis (Chofoza ukuze ukhulise!)

Isizinda se-ultrasonic sisekelwe ku-cavitation yama-acoustic namandla ayo we-hydrodynamic shear

I-Hielscher Ultrasonics ikhiqiza ama-ultrasonicators asebenzayo ngokugcwele okuvela ku-spectrum.

I-ultra-power ultrasonic extractors kusukela ebhayisini kuya ku-pilot kanye nesilinganiso sezimboni.