I-Hielscher Ultrasound Technology

Isizinda se-Ultrasonic se-Polysaccharides kusuka ku-Astragalus Membranaceus Umsuka

  • Izimpande ze-Astragalus membranceus (ebizwa nangokuthi i-Astragalus propinquus) ziqukethe i-saponin cycloastragenol, engase isebenzise i-telomerase futhi ngaleyo ndlela yandisa ubude be-telomeres. Ubude be-Telomere buhlobene nokuphila isikhathi eside.
  • Isizinda se-ultrasonic yindlela ephakeme yokuhlukanisa i-cycloastragenol namanye ama-phytochemicals abalulekile avela ku-Astragalus radix.
  • I-Sonication iyi-process non-thermal, elula futhi esheshayo, evumela ukukhiqiza okukhishwa okuphezulu kwe-Astragalus.

I-Astragalus Compounds

I-Astragalus polysaccharides ibalulekile izingxenye ze-bioactive ze-Astragali Radix, impande eyomile ye-Astragalus membranaceus. I-polysaccharides ye-Astragali Radix isetshenziselwa kakhulu imithi yesintu yamaShayina. Izimpande ze-Astragalius propinquus, eyaziwa ngokuthi i-Radix Astragali, zicebile kuma-phyto-amakhemikhali afana ne-polysaccharides, i-triterpenoids (isib. I-astragalosides njenge-Astragaloside IV), isoflavones (isb. Kumatakenin, calycosin, ifononetin) kanye nama-glycosides nama-malonate. I-saponin cycloastragenol, isakhi esitholakala ku-A. propinquus, ingase isebenze i-telomerase futhi ngaleyo ndlela yandisa ubude be-telomeres. I-Telomeres yiyona evikelayo “i-cap” ekupheleni kwe-DNA strand ekupheleni kwawo wonke ama-chromosomes. Ukuncishiswa kwe-Telomere kuhlobene nokuguga. Ukwengezwa nge-astragalus i-cycloastragenol ingase ikhulise ama-telomeres futhi ibambezele ukuguga.

Isizinda se-ultrasonic se-Phyto-Chemicals

I-Sonication iyaziwa njengendlela yokuqinisa isikhamo. I-cavitation ye-Ultrasonic iholela ekuqhekekeni kwendonga yesitshalo sesitshalo, ngaleyo ndlela ukwandisa isivuno se-polysaccharides. Isizinda se-Ultrasonic sisebenzise ngempumelelo ukukhipha ama-Astragalus polysaccharides ngenzuzo yokwanda kwesivuno sesithamo nokunciphisa isikhathi sokukhipha.
I-ultrasonication ingasetshenziswa ezintweni ezihlukahlukene zezitshalo ezifana namaqabunga, iziqu, izimbali nezimpande.
Inqubo yesikhumba se-ultrasonic iyindlela engavamile, evumayo yokumaketha, engasetshenziswa ekushiseni okukhethiwe ngokuqondile. Njengoba kuphelile ngokwanele, izinto zokushisa ezibucayi zingasetshenziswa ngaphandle kwesib. Isib by ultrasonic ezibandayo amanzi. Nge sonication, amanzi noma solvents ingasetshenziswa njengoba liquid. Lokhu kuvumela ukuguqulwa kahle kwezimiso zezizinda kumakhemikhali ahlosiwe.

Isizinda se-Ultrasonic ne-UP100H

Izinzuzo ze-Ultrasonic Astragalus Extraction:

  • isivuno esiphezulu
  • Ikhwalithi ephezulu
  • Ukukhipha okusheshayo
  • Inqubo Ebukhali, Engekho Eyashisayo
  • Amanzi noma Isixazululo
  • Okulula & Ukusebenza okuphephile
Amakhemikhali akhuthazayo ezempilo wezimpande ze-Astragalus angenziwa ngokuphumelelayo nge-ultrasonication.

I-Astragalus membranaceus

Isicelo solwazi




Qaphela kwethu Inqubomgomo yobumfihlo.


Ukusebenza okuphezulu kwe-Ultrasonicators

Hielscher Ultrasonics’ Imishini yokukhishwa kwe-ultrasonic isetshenziselwa emhlabeni jikelele ukulungiselela izitshalo eziphezulu ze-botanicals. Ama-phyto-amakhemikhali asetshenzisiwe nge-Ultrasonically asetshenziselwa imiphumela yabo yokwelapha kanye nezinzuzo zezempilo ku-pharma, ukwengezela, kanye nemikhiqizo yokudla. I-Hielscher inikeza i-spectrum egcwele kusuka kumabhanki amancane abamba ama-ultrasonicators kuma-ultrasonic ama-industrial for the production line inline. Ukuqina kwemishini ye-ultrasonic ye-Hielscher kuvumela ukusebenza komsebenzi we-24/7 emsebenzini obuthakathaka nasezindaweni ezinzima. Esinye isici esibalulekile samaphrosesa ase-Hielscher ase-ultrasonic ukulawula okuqondile phezu kwemigomo yezinqubo kanye nokurekhoda kwedatha okuzenzakalelayo yalezo zimingcele. Lokhu kwenza imiphumela ye-reproducible futhi inqubo yokusebenza.
Ithebula elingezansi linikeza isibonakaliso somthamo wokucubungula we-ultrasonicators wethu:

Iqoqwana Ivolumu flow Rate Amadivayisi ezinconyiwe
1 kuya ku-500mL 10 kuya ku-200mL / min UP100H
10 kuya ku-2000mL 20 kuya ku-400mL / min UP200Ht, UP400St
0.1 kuya ku-20L 0.2 kuya ku-4L / min I-UIP2000hdT
10 kuya ku-100L 2 kuya ku-10L / iminithi I-UIP4000hdT
na 10 kuya ku-100L / iminithi UIP16000
na sikhulu yinhlanganisela UIP16000

Xhumana nathi! / Cela Us!

Cela ulwazi oluthe xaxa

Sicela usebenzise ifomu elingezansi, uma ufisa ukucela ulwazi oluthe xaxa mayelana ne-homogenization yama-ultrasonic. Sizojabula ukukunikeza uhlelo lwe-ultrasonic ukuhlangabezana nezidingo zakho.









Sicela uqaphele wethu Inqubomgomo yobumfihlo.


Izincwadi / Izinkomba

  • Li, L., Hou, X., Xu, R., Liu, C., Tu, M. (2017): Ukubuyekezwa kocwaningo ngemiphumela yemithi ye-astragaloside IV. I-Fundam Clin Pharmacol, 31: 17-36.

Izinzuzo ze-Ultrasonic Extraction

  • Izitshalo eziphezulu zekhwalithi
  • isizinda esiphelele ngokwengeziwe
  • izinga eliphezulu lokukhipha
  • Ukukhishwa kwe-spectrum ephelele
  • Ukusetshenziswa kwama-solvents ahlukahlukene
  • non-toxic
  • Indlela engeyona eyashisayo (ebandayo)
  • Inqubo yokukhipha ngokushesha
  • Kuphephile futhi kulula ukuyisebenzisa
  • ukusabalalisa okulinganayo
I-Hielscher Ultrasonics ikhiqiza ama-ultrasonicators aphezulu ekusebenzeni kwezicelo ze-sonochemical.

Amaprosesa aphezulu aphezulu e-ultrasonic kusukela ebhuthini kuya ku-pilot nesilinganiso sezimboni.

Amaqiniso Okufanele Ukwazi

Astragalus propinquus

I-propinquus A. iyisitshalo sezimbali sase-Asia, esitholakala kakhulu e-Asia, esaziwa nangokuthi i-Astragalus membranceus, isixuku se-milk milk vetch noma i-Huang qi. E-Chinese Traditional Medicine (TCM), i-Astragalus ingenye yamakhambi ayisisekelo angu-50. I-Astragalus icebile kuma-polysaccharides, ama-triterpenoids, ama-isoflavones (isb. Kumatakenin, calycosin, ifononetin) kanye nama-glycosides nama-malonate. I-Astragaloside IV inqunywe njengenye yezinto ezinkulu kanye ezisemqoka ze-Astragalus membranaceus. Ucwaningo lubonisa ukuthi i-Astragaloside IV inemiphumela yokuzivikela ekugxilweni kwe-cerebral ischemia / ukuphindaphinda, isifo senhliziyo, isifo se-pulmonary, cirrhosis yesibindi, ne-nephropathy yesifo sikashukela. Ubufakazi obandayo busekela ukuphathwa kwe-Astragaloside IV ekwelapheni i-organ fibrosis, impendulo yokuvuvukala, ukucindezeleka kwe-oxidative, ne-apoptosis
Ucwaningo lwezemvelo lubonisa ukuthi i-Astragalus membranaceus ekhishwayo, eyakhiwa yi-polysaccharides, i-flavonoids, i-saponins namanye ama-phyto-amakhemikhali, ingandisa umsebenzi we-telomerase, futhi ine-antioxidant, anti-inflammatory, immunoregulatory, antiticancer, i-hypolipidemic, i-antihyperglycemic, i-hepatoprotective, i-neuroprotective, i-expectorant, i- kanye nemiphumela ye-diuretic.

I-Telomeres

I-Telomeres yizona zakhiwo ekupheleni kwama-chromosomes ngokuvamile avame ukufaniswa nekhanda ekugcineni kwejazi lesikhumba. Umsebenzi wabo ukuvimbela ijazi lesicathulo ngokumelene nokukhwabanisa. I-Telomeres inomsebenzi ofanayo wokuvikela emaphethelweni we-DNA emigqonyeni kuma-chromosomes. Ukuncishiswa kwe-Telomere kuyahambisana nokuguga. Ama-telomeres anciphisa phakathi nokuhlukaniswa kweseli bese ekugcineni asho isimo sokungabikho ukuboshwa kokuboshwa, okuyaziwa njenge-senescence yeselula.
I-Telomeres ibonakala ngokulandelana kwe-TTAGGG futhi inamaprotheni ahlobene ahlangene, abizwa ndawonye njengama-protein ase-shelter, adlala indima ebalulekile ekusimeni kwe-chromosome, umthethonqubo wezakhi, umdlavuza kanye nesenescence yeselula.

I-Polysaccharides

I-polysaccharides yi-biomacromolecules enamanye ama-monosaccharides ayishumi noma ngaphezulu okungafani nesakhiwo neshukela. Ama-polysaccharides ama-molecule e-polymeric carbohydrate akha ngamaketanga amade amamonithi e-monosaccharide ahlanganiswe ndawonye ngokuhlanganiswa kwe-glycosidic, futhi lapho i-hydrolysis inikeza ama-monosaccharides noma ama-oligosaccharides. Ihamba ngokuhlelwa kusuka kulayini kuya ku-branched kakhulu. Ucwaningo lubonise ukuthi i-Astragalus polysaccharides iqukethe i-glucose, ngaphezu kwe-rhamnose, i-galactose, i-arabinose, i-xylose, i-mannose, i-glucuronic acid, ne-galacturonic acid.