I-Hielscher Ultrasound Technology

I-Ultrasonic Decarboxylation yama-Cannabinoids

Ama-cannabinoids ama-decarboxylated njenge-CBD, i-THC kanye ne-CBG phakathi kwamanye amaningi aziwa njengefomu elisebenzayo, elibonisa imiphumela ethinta kakhulu futhi ephumelelayo emzimbeni womuntu (isb uhlelo lwe-endocannbinoid). I-Ultrasonication iyindlela ephumelela kakhulu yokukhipha ama-decarboxylate cannabinoids (isb., I-CBDA, i-THCA, i-CBGA) kumafomu awo asebenza ngokweqile (isib, i-CBD, i-THC, i-CBG).

I-Decarboxylate Cannabinoids nge-Sonication

Cannabinoids such as CBD, THC, CBG etc. are extracted and decarboxylated by ultrasonication. I-CBD yaziwa kakhulu ngemiphumela yayo yokukhuthaza ezempilo kanye nokwelapha. Kepha kuzo zombili izinhlobo zesitshalo se-cannabis, e-hemp nensangu, kutholakala ikakhulukazi i-cannabidiolic acid (CBDA), kanti i-cannabidiol (CBD) itholakala kuphela ngamanani amancane.
What is the difference between CBD and CBDA?
I-CBDA ingumanduleli we-CBD futhi ineqembu eline-asidi elinamathele kumolekyuli ye-CBD, okuthiwa yi-carboxyl-group. Kokubili, i-CBD ne-CBDA, yizinto ezingadakisi, ezingezona ezokusebenza kwengqondo, okusho ukuthi azivezi umphumela "ophezulu". Kepha imiphumela ye-bioactive ye-CBD ne-CBDA yehluke kakhulu. I-CBDA iyifomu engathathi hlangothi, engasebenzi kakhulu, ngenkathi – lapho i-decarboxylated ibe yi-CBD – ama-molecule e-CBD agcwalisa imiphumela yawo ephelele yokukhuthaza impilo njenge-supplement yezemithi kanye nokudla.
I-decarboxylation ithinta zonke ezinye izinhlobo ze-acidic cannabinoid ezifana ne-THCA, i-CBGA nezinye. Iqembu le-carboxyl liyasuswa ukuze amafomu asebenzayo, isib, i-CBD, i-∆⁹9-THC (iTHC), i-CBG njll.
Ultrasonic decarboxylation turns the less active form into the more active cannabinoid form by removing the carboxyl group via intense ultrasound waves.

I-Ultrasonic Cannabinoid Decarboxylation

I-decarboxylation (i-decarbing) isinyathelo esivamile ekusetshenzisweni kwe-cannabis. Enqubeni ejwayelekile yokuhlukanisa, abakhiqizi basebenzisa ukushisa okomile ezingxenyeni zezitshalo ezintsha ukuze kuguqulwe i-CBDA ibe yi-CBD, ∆9-THC-acid (THCA) ibe yi-∆9-THC (THC), i-CBGA ibe yi-CBG njll. pre-processing step ngaphambi kokukhishwa futhi kudinga isikhathi namandla.
I-ultrasonic decarboxylation idlula i-decarboxylation ejwayelekile ngezinzuzo ezahlukahlukene. Okokuqala, i-ultrasonic decarboxylation akuyona inqubo eyengeziwe yenqubo, kepha kwenzeka ngasikhathi sinye lapho ama-cannabinoids ekhishwa nge-ultrasonication kusuka ku-hemp noma insangu. Ukwelashwa kwe-Ultrasonic cannabis kuyindlela ephezulu yokukhipha kanyekanye ne-decarboxylation ye-phytocannabinoids. Inqubo ye-ultrasonic idlula ngamanani aphezulu wokukhipha kanye ne-decarboxylation ngaphansi kwamazinga okushisa alawulwayo nezikhathi zokwelashwa ezimfushane. Lokhu kuvimbela ama-phytocannabinnoids ngokumelene nokubola: Kokukhishwa kwe-cannabinoid kwe-ultrasonically decarboxylated, akukho cannbinol (CBN) etholakalayo. i-cannabinol ingumkhiqizo ojwayelekile we-oxidation futhi umaka wekhwalithi. Lokhu kusho ukuthi imiphumela ye-ultrasonic decarbing kukhishwe ikhwalithi ephezulu ye-cannabis.
Furthermore, all ultrasonically obtained extraction and decarboxylation results are fully repeatable and reproducible. As all ultrasonic process parameters are precisely controllable, extraction and decarboxylation results can be reproduced with reliability. This enables producers to standardize their process and to offer their customers cannabis extracts of continuously highest quality.

Ultrasonication is used to decarboxylate acidic cannabinoids (CBDA, THCA, CBGA) into their active forms such as CBD, THC and CBG.

I-ultrasonicator UP400St ingasetshenziselwa i-decarboxylation kanyekanye nokukhishwa kwama-cannabinoids avela ku-Cannabis Sativa L.

Isicelo solwazi




Qaphela kwethu Inqubomgomo yobumfihlo.


Izinzuzo ze-Ultrasonic Decarboxylation

  • Ukukhipha kanyekanye ne-decarboxylation
  • Inqubo Ebukhali, Engekho Eyashisayo
  • Ukwelashwa okusheshayo
  • Akukho ukubola kwama-cannabinoids
  • Ukuphindeka, ukukhiqiza kabusha
  • Kulula Futhi Kuphephile Ukusebenza
  • Iyatholakala nganoma iyiphi ivolumu
  • Ikhwalithi yomkhiqizo ezimile

Ungayinquma kanjani i-Cannabinoids nge-Sonication

I-Sonication ingaguqula ama-cannabinoids ane-asidi njenge-CBDA, ∆9-THC-acid / TCA, CBGA njll ezinhlotsheni ze-CBD, i--9-THC, i-CBG njll. Ukuthola i-decarboxylation nge-ultrasonication, ukwelashwa kwe-ultrasound kuhlanganiswe ne ukwelashwa kokushisa. Lokhu kwaziwa njenge-thermo-sonication. Izithelo ezinhle ze-CBD, ∆9-THC, ne-CBG zitholakala ku-110 ° C.

Ama-cannabinoids nemiphumela yawo emzimbeni womuntu

Isitshalo seCannabis Sativa L. sicebile ngezinhlobo ezingaphezu kuka-113 zama-cannabinoid. Isibonelo, i-CBD, i-CBDA, i-THC, i-THCA, i-CBG ne-CBGA phakathi kokunye konke kungama-cannabinoids (abizwa nangokuthi ama-phytocannabinoids) atholakala kusitshalo se-cannabis. Ama-cannabinoids nawo atholakala emzimbeni womuntu, lapho asebenza njengama-molecule okusayina ohlelweni lwe-endocrine. Ama-cannabinoids akhiqizwa ngumzimba womuntu aziwa ngokuthi ama-endocannabinoids. Ama-Endocannabinoids asebenza njengama-neurotransmitters abopha kuma-cannabinoid receptors. Uhlelo lwebhayoloji lwe-endocannabinoids kanye ne-cannabinoid receptors lubizwa ngokuthi uhlelo lwe-endocannabinnoid futhi ludlala indima ebalulekile ekulawulweni kwemisebenzi yomzimba.
Njengoba i-cannabinoids etholakala ezitshalweni ingangena emadokhumeni e-cannabinoid womuntu, ama-cannabinoids anikezwa njengokwelashwa / ukwelashwa futhi njengezithako zokudla ezikhuthaza impilo.

UIP2000hdT for decarboxylation of cannabinoids from Cannabis Sativa L.

I-UIP2000hdT i-decarboxylation yama-cannabinoids ane-asidi (isib. i-cannabinoidic acid i-CBDA) ku-cannabidiol esebenzayo (i-CBD)

Ama-Ultrasonic Extractors we-Cannabinoid Decarboxylation

Isizinda se-Ultrasonic kanye ne-decarboxylation ubuchwepheshe bokusebenza obunokwethenjelwa, obusiza futhi busheshise ukukhiqizwa kokukhishwa kwekhwalithi ephezulu ye-cannabinoid esitshalweni se-Cannabis Sativa L. (i-hemp nensangu). Iphothifoliyo yeHielscher Ultrasonics ifaka uhla oluphelele kusuka kuma-compact lab ultrasonicators kuya kumasistimu wokukhipha ezimbonini. Ngaleyo ndlela, thina kwaHielscher singakunikeza i-ultrasonicator efaneleke kakhulu kunqubo yakho ebekiwe yenqubo. Abasebenzi bethu besikhathi eside abanolwazi bazokusiza ekuhlolweni okungenzeka nasekusebenziseni inqubo ekufakweni kohlelo lwakho lwe-ultrasonic ezingeni lokugcina lokukhiqiza.
Ukuphrinta konyawo okuncane kwama-extractors ethu e-ultrasonic kanye nokuguquguquka kwawo ekukhethweni kokufaka kubenza balingane ngisho nasendaweni elinganiselwe kakhulu yezindawo zokucubungula i-cannabis. Amaprosesa we-Ultrasonic afakiwe emhlabeni wonke ezindaweni zokukhiqiza zokudla, i-pharma nezomsoco.

Isistimu Yokukhishwa Ephucukile Ne-Decarboxylation Systems

Iphothifoliyo yomkhiqizo we-Hielscher Ultrasonics ihlanganisa uhla oluphelele lwe-ultrasonicator ephezulu yokusebenza yokukhipha kanye ne-decarboxylation kusuka kokuncane kuya kokukhulu. Izesekeli ezingeziwe zivumela ukuhlangana okulula kokucushwa okuhle kakhulu kwedivayisi ye-ultrasonic ngenqubo yakho ye-cannabis / decarboxylation. Ukusetha okulungile kwe-ultrasonic kuya ngomthamo ocatshangelwe, ivolumu, impahla eluhlaza, inqubo ye-batch noma i-inline kanye nomugqa wesikhathi.

I-Batch ne-Inline

Ama-ultrasonicators ama-Hielscher angasetshenziselwa ukuqhutshwa nokuqhutshwa kokugeleza okuqhubekayo. Ukucubungula kwe-batch ultrasonic kufanelekile ekuhlolweni kwenqubo, ukwenziwa kahle futhi kube sezingeni eliphansi lokukhiqiza likasayizi ophakathi. I-Ultrasonic decarboxylation ye-acidic phyto-cannabinoids (isib., I-CBDA, i-THCA, i-CBGA) ingenzeka ku-beaker evulekile noma evaliwe ye-ultrasonic kanye nasekwelapheni okuqhubekayo kusetshenziswa i-ultrasonic flow cell reactor .. I-Hielscher Ultrasonics inesizinda esifaneleka kakhulu ne-decarboxylation ukusetha ivolumu yakho ye-cannabis nezinqubo zenqubo.

Ama-Ultrasonic Extractors wawo wonke amandla womkhiqizo

UIP4000hdT flow flow cell for sonication inline esikalini ezimboniniUhla lomkhiqizo we-Hielscher Ultrasonics lumboza ububanzi obugcwele bama-processor we-ultrasonic kusuka kuma-compact lab ultrasonicators ngaphezulu kwebench-top kanye nezinhlelo zokushayela kumaprosesa asezimboni asebenza ngokugcwele anamandla wokucubungula ukulayisha amaloli ngehora. Uhla oluphelele lomkhiqizo lusivumela ukuthi sikunikeze nge-ultrasonic extractor / decarboxylator efaneleke kakhulu yempahla yakho eluhlaza ye-cannabis, amandla enqubo nezinhloso zokukhiqiza.
Izinhlelo ze-Ultrasonic benchtop zilungele ukuhlolwa okungenzeka nokusebenza kwenqubo. Ukulinganiswa komugqa ngokuya ngemingcele yenqubo esungulwe kwenza kube lula kakhulu ukukhulisa amandla wokucubungula kusuka ezinkatho ezincane kuya ekukhiqizeni ngokugcwele ukuthengisa. Ukukhuphula amandla kungenziwa ngokufaka iyunithi enamandla kakhulu yokukhipha i-ultrasonic noma ukuhlanganisa ama-ultrasonicators amaningi ngokufana. Nge-UIP16000, i-Hielscher inikeza i-extractor ye-ultrasonic enamandla kunazo zonke emhlabeni.

Ama-Amplitudes Alawulekayo Kahle Emiphumela Engcono

Onke ama-ultrasonicators aseHielscher alawulwa kahle futhi ngaleyo ndlela enokwethenjelwa amahhashi omsebenzi ekukhiqizeni. I-amplitude ingenye yezinqubo ezibalulekile zenqubo ezithonya ukusebenza kahle nokusebenza kahle kwe-ultrasonic isizinda se-Cannabis Sativa L. kanye ne-decarboxylation kanyekanye yama-cannabinoids.
Hielscher's industrial processors of the hdT series can be comfortable and user-friendly operated via browser remote control.Zonke Hielscher Ultrasonics’ amaprosesa avumela ukumiswa okuqondile kwe-amplitude. I-Sonotrodes nezimpondo ze-booster yizinsiza ezivumela ukuguqula ubukhulu endaweni ebanzi kakhulu. Amaprosesa aseHielscher ezimboni ze-ultrasonic angaletha ama-amplitudes aphakeme kakhulu futhi ahambise amandla adingekayo e-ultrasonic wezicelo ezifunwayo. Amplitudes afika ku-200µm angaqhutshwa ngokuqhubekayo ngokuqhubekayo ekusebenzeni okungama-24/7.
Amasethingi we-amplitude aqondile nokuqapha unomphela kwemingcele yenqubo ye-ultrasonic nge-smart software kukunikeza ithuba lokuphatha impahla yakho ye-cannabis ngezimo ezisebenza kahle kakhulu ze-ultrasonic. I-sonication efanelekile yokukhipha okungcono nemiphumela ye-decarboxylation!
Ukuqina kwemishini ye-ultrasonic ye-Hielscher kuvumela ukusebenza kwe-24/7 emsebenzini osindayo nasezindaweni ezifunayo. Lokhu kwenza imishini ye-ultrasonic ye-Hielscher ithuluzi lomsebenzi elithembekile eligcwalisa izidingo zakho zokukhishwa.

Ukuhlola okulula, okungenazingozi

Izinqubo ze-Ultrasonic zingalinganiswa ngokuphelele. Lokhu kusho ukuthi yonke imiphumela oyizuzile usebenzisa ilebhu noma ibhentshi-phezulu i-ultrasonicator, ingakalwa ngokukhishwa okufanayo kusetshenziswa amapharamitha wenqubo efanayo. Lokhu kwenza i-ultrasonication ilungele ukuhlolwa okungenakho ubungozi, ukwenziwa kwenqubo nokwenza okulandelayo kokukhiqizwa kwezentengiso. Xhumana nathi ukuze ufunde ukuthi i-sonication ingakhuphula kanjani umkhiqizo wakho wokukhipha insangu.

Ikhwalithi ephezulu kakhulu – Yakhelwe Yakheka EJalimane

Njengebhizinisi eliphethwe ngumndeni neliphethwe ngumndeni, i-Hielscher ibeka phambili amazinga aphezulu ekhwalithi yamaprosesa ayo e-ultrasonic. Onke ama-ultrasonicators aklanyelwe, akhiqizwa futhi ahlolwa kahle ekomkhulu lethu lasekhaya eTeltow ngaseBerlin, eJalimane. Ukuqina nokuthembeka kwemishini ye-ultrasonic ye-Hielscher kuyenza ihhashi lomsebenzi ekukhiqizeni kwakho. Ukusebenza okungu-24/7 ngaphansi kokulayishwa okuphelele futhi ezindaweni ezifuna kakhulu kuyisici semvelo sama-ultrasonicators asebenza kahle kakhulu kaHielscher.

Ithebula elingezansi linikeza isibonakaliso somthamo wokucubungula we-ultrasonicators wethu:

Iqoqwana Ivolumu flow Rate Amadivayisi ezinconyiwe
1 kuya ku-500mL 10 kuya ku-200mL / min UP100H
10 kuya ku-2000mL 20 kuya ku-400mL / min UP200Ht, UP400St
0.1 kuya ku-20L 0.2 kuya ku-4L / min I-UIP2000hdT
10 kuya ku-100L 2 kuya ku-10L / iminithi I-UIP4000hdT
na 10 kuya ku-100L / iminithi UIP16000
na sikhulu yinhlanganisela UIP16000

Xhumana nathi! / Cela Us!

Cela ulwazi oluthe xaxa

Uyacelwa ukuthi usebenzise ifomu elingezansi ukucela ulwazi olungeziwe mayelana nezinhlelo zokusebenza ze-ultrasonic, izinhlelo zokusebenza nentengo. Sizokujabulela ukuxoxa ngenqubo yakho nawe futhi sikunikeze uhlelo lwe-ultrasonic oluhlangabezana nezidingo zakho!









Sicela uqaphele wethu Inqubomgomo yobumfihlo.


Ultrasonic high-shear homogenizers are used in lab, bench-top, pilot and industrial processing.

I-Hielscher Ultrasonics ikhiqiza ama-homogenizers asebenza ngokusebenza okuphezulu wokuxuba izinhlelo, ukusabalalisa, ukumisa nokukhipha ilebhu, umshayeli kanye nesikali sezimboni.



Amaqiniso Okufanele Ukwazi

Kungani ama-Decarboxylate Cannabinoids?

I-Decarboxylation inqubo yamakhemikhali lapho kususwa uchungechunge lwamakhemikhali njengeqembu le-carboxyl kwi-molecule. Esitshalweni se-cannabis, iningi lama-cannabinoids akhona ngendlela yawo ene-asidi njenge-CBDA, i-THCA, i-CBGA njll. Amafomu e-acidic aneqembu le-carboxyl elihlanganisiwe futhi laziwa njengefomu elingasebenzi kangako. Lawo mafomu ane-asidi ayizandulela zamafomu we-cannabinoid asebenzayo (isib. I-CBD, i-∆⁹9-THC, i-CBG njll.). Okwemithi yokwelapha, izithako zokwelapha nezempilo, ifomu le-decarboxylated, elisebenza kakhulu lama-cannabinoids kungenxa yezizathu ezisobala ezikhethwayo.
Ngakho-ke, iqembu le-acidic carboxyl lisuswa kuma-cannabinoids ngenqubo ebizwa nge- "decarboxylation".
Isibonelo, i-cannabis ingahlukaniswa nge-decarboxylated (colloquially also "decarbed") ngokusebenzisa ukushisa okomile. I-decarboxylation nayo iyenzeka lapho i-cannabis ishiywa ukwelashwa. Ngesikhathi sokuphulukiswa, uchungechunge lwe-carboxyl lwehla kancane, okuyinqubo edla isikhathi. Uma lokhu kwenzeka, i-CBDA namanye ama-cannabinoids ane-asidi alahlekelwa yi-asidi yawo. ngaleyo ndlela sisebenze ngokwengeziwe. I-Decarboxylation ingasheshiswa ngezinye izinqubo, njenge-thermo-sonication.

Mangaki ama-cannabinoids akwi-cannabis yami ekhishwe?

Ukuhlungwa kwama-cannabinoids kokukhishwayo kuncike kakhulu ohlotsheni lwesitshalo (uhlobo lwe-cannabis), indlela yokukhipha nokuthi ngabe isitshalo senziwe i-decarboxylated noma cha.