Ukukhiqiza Okunenzuzo Kwe-Hydrogel nge-Ultrasonication

I-Sonication iyindlela esebenza kahle kakhulu, ethembekile futhi elula yokulungiselela ama-hydrogel asebenza kahle. Lawa ma-hydrogel anikezela ngezinto ezinhle kakhulu ezifana namandla wokumunca, i-viscoelasticity, amandla womshini, i-compression modulus, kanye nemisebenzi yokuziphilisa.

I-Ultrasonic Polymerization kanye nokuhlakazeka kweHydrogel Production

Ultrasonication is used to initiate cross-linking and polymerization during hydrogel production. Ultrasonic dispersion is used to distribute nanoparticles in hydrogels.Ama-Hydrogels angama-hydrophilic, ama-three-dimensional polymeric network akwazi ukumunca amanzi amaningi noma uketshezi. Ama-Hydrogel akhombisa amandla okuvuvukala angajwayelekile. Amabhulokhi wokwakha ama-hydrgel afaka phakathi i-polyvinyl alcohol, i-polyethylene glycol, i-sodium polyacrylate, ama-acrylate polymers, ama-carbomers, ama-polysaccharides noma ama-polypeptides anenani eliphezulu lamaqembu e-hydrophilic, namaprotheni emvelo afana ne-collagen, i-gelatine ne-fibrin.
Okubizwa ngokuthi yi-hybrid hydrogels kuqukethe izinto ezahlukahlukene ezingamakhemikhali, ezisebenzayo nezokuziphatha, njengamaprotheni, ama-peptides, noma ama-nano- / microstructures.
Ukusabalalisa kwe-Ultrasonic kusetshenziswa kabanzi njengenqubo esebenza kahle kakhulu futhi ethembekile yokwenza izinto ze-nano ezifana ne-carbon nanotubes (i-CNTs, i-MWCNTs, i-SWCNTs), i-cellulose nano-crystals, i-chitin nanofibres, i-titanium dioxide, ama-nanoparticles esiliva, amaprotheni nezinye izinto ze-micron- noma i-nanostructures kumatrix we-polymeric wama-hydrogel. Lokhu kwenza i-sonication ithuluzi eliyinhloko lokukhiqiza ama-hydrogel asebenza kakhulu anezimfanelo ezingavamile.

Isicelo solwazi




Qaphela kwethu Inqubomgomo yobumfihlo.


Ultrasonic cavitation promotes the cross-linking and polymerization during hydrogel synthesis. Ultrasonic dispersion facilitates the uniform distribution of nanomaterials for hybrid hydrogel fabrication.

I-Ultrasonicator I-UIP1000hdT nge-glass reactor ye-hydrogel synthesis

Okukhonjiswa Ucwaningo – Ukulungiselela i-Ultrasonic Hydrogel

Okokuqala, i-ultrasonication ithuthukisa ukuphendula kwe-polymerization kanye ne-cross-linking reaction ngenkathi kwakhiwa i-hydrogel.
Okwesibili, i-ultrasonication ibonakaliswe njengenqubo yokusabalalisa ethembekile nephumelelayo yokukhiqiza ama-hydrogel nama-nanocomposite hydrogels.

I-Ultrasonic Cross-Linking kanye ne-Polymerization yama-Hydrogels

I-Ultrasonication isiza ukwakheka kwamanethiwekhi e-polymeric ngesikhathi se-hydrogel synthesis ngesizukulwane samahhala esinamandla. Amagagasi amakhulu e-ultrasound akhiqiza i-acoustic cavitation edala amandla amakhulu okushefa, ukucheba kwamangqamuzana nokwakheka okukhululekile okukhulu.

UCass et al. (2010) kwalungiswa ama- “acrylic hydrogels” amaningi alungiswa nge-ultrasonic polymerization yama-monomers ancibilikiswa ngamanzi nama-macromonomers. I-Ultrasound yasetshenziselwa ukudala ama-radicals okuqala kuma-viscous aqueous monomer soluions kusetshenziswa izithasiselo i-glycerol, sorbitol noma i-glucose ohlelweni oluvulekile ku-37 ° C. Izithasiselo ezincibilikayo zamanzi zazibalulekile ekukhiqizeni i-hydrogel, i-glycerol iyona ephumelela kakhulu. Ama-Hydrogels alungiswa kusuka kuma-monomers 2-hydroxyethyl methacrylate, poly (ethylene glycol) dimethacrylate, dextran methacrylate, acrylic acid / ethylene glycol dimethacrylate ne-acrylamide / bis-acrylamide. ” [UCass et al. 2010] Ukusetshenziswa kwe-Ultrasound kusetshenziswa iphenyo i-ultrasonicator kwatholakala kuyindlela ephumelelayo yokwenza i-polymerization yama-monomers e-soluble vinyl amanzi kanye nokulungiselelwa okwalandela kwama-hydrogel. I-polymerization eqalwe nge-ultrasonically yenzeka ngokushesha ngokungabikho kwesiqalisi samakhemikhali.

Ukuhlakazeka kwe-Ultrasonic kweNano-Silica

Ukuhlakazeka kwe-Ultrasonic

  • ama-nanoparticles, isb. i-TiO2
  • ama-carbon nanotubes (CNTs)
  • ama-nanocrystals e-cellulose (ama-CNC)
  • ama-nanofibrils e-cellulose
  • izinsini, isib xanthan, sage seed gum
  • amaprotheni
Ultrasonic nano-dispersion with the i-ultrasonicator UP400St


Hydrogel formation via ultrasonically-assisted gelation using the ultrasonicator UP100H

Ukwakhiwa kwe-Hydrogel nge-gelation esizwe nge-ultrasonically kusetshenziswa i-ultrasonicator UP100H

Isicelo solwazi




Qaphela kwethu Inqubomgomo yobumfihlo.


I-Ultrasonication iyahambisana nazo zonke izinhlobo zama-polymers nama-biopolymers futhi ivumela ukuqinisa ama-hydrogels e-hybrid ngezinto ezakhiwe nge-nano ezifana nama-nanoparticles, ama-nanocrystals noma ama-nanofibres. Ukuqinisa ama-hydrogel anama-nanomaterial ahlukahlukene kuvumela ukuguqula nokulawula izakhiwo ze-physicochemical kanye ne-rheo-mechanical ye-nanocomposite hydrogels, ngoba ama-microstructures ayisici esiyinhloko sezinto ezitholakalayo.

Ultrasonication is applied to produce high-performance hydrogels containing nano-materials

I-SEM ye-poly (i-acrylamide-co-itaconic acid hydrogel equkethe i-MWCNTs. Ama-MWCNTs ahlakazeka nge-ultrasonically kusetshenziswa i-ultrasonicator UP200S.
isifundo nesithombe: Mohammadinezhada et al., 2018

Ukwenziwa kwePoly (i-acrylamide-co-itaconic acid) – I-MWCNT Hydrogel isebenzisa i-Sonication

Mohammadinezhada et al. (2018) ikhiqize ngempumelelo i-superabsorbent hydrogel composite equkethe i-poly (i-acrylamide-co-itaconic acid) nama-carbon nanotubes anezindonga eziningi (i-MWCNTs). I-Ultrasonication yenziwa ngedivayisi ye-Hielscher ultrasonic UP200SUkusimama kwe-hydrogel kukhuphuke ngokwanda kwama-MWCNTs ratios, okungabangelwa isimo se-hydrophobic se-MWCNTs kanye nokwanda kwe-crosslinker density. Umthamo wokugcinwa kwamanzi (WRC) we-P (AAm-co-IA) hydrogel nawo wenyuswa lapho kukhona i-MWCNT (10 wt%). Kulolu cwaningo, imiphumela ye-ultrasonication ibalwe njengephakeme maqondana nokusatshalaliswa okufanayo kwe-carbon nanotubes ebusweni be-polymer. Ama-MWCNTs abephelele ngaphandle kokuphazamiseka esakhiweni se-polymeric. Ngokwengeziwe, amandla we-nanocomposite etholakele nomthamo wokugcinwa kwamanzi nokufakwa kwezinye izinto ezincibilikayo njenge-Pb (II) kwandisiwe. I-Sonication yephule i-initiator futhi yahlakaza ama-MWCNTs njengokugcwalisa okuhle kakhulu kumaketanga e-polymer ngaphansi kokushisa okwandayo.
Abaphenyi baphetha ngokuthi lezi "zimo zokuphendula azikwazi ukufinyelelwa ngezindlela ezivamile, futhi ukufana nokusabalalisa okuhle kwezinhlayiya kumphathi akunakutholakala. Ngaphezu kwalokho, inqubo ye-sonication ihlukanisa ama-nanoparticles ku-particle eyodwa, ngenkathi inyakazisa ayikwazi ukwenza lokhu. Enye indlela yokwehlisa usayizi umphumela wamagagasi anamandla e-acoustic ezihlangwini zesibili njengokuhlanganiswa kwe-hydrogen lapho le irradiation yephula ukuhlangana kwe-H kwezinhlayiya, futhi ngemuva kwalokho, ihlukanisa izinhlayiya ezihlanganisiwe futhi yenyuse inani lamaqembu ezikhangiso amahhala njenge -OH kanye ukufinyeleleka. Ngakho-ke, lokhu kwenzeka okubalulekile kwenza inqubo ye-sonication ibe yindlela ephakeme kunezinye njengokuvusa amandla kazibuthe asetshenziswe emibhalweni. ” [Mohammadinezhada et al., 2018]

Ama-Ultrasonicators Wokusebenza Okuphezulu we-Hydrogel Synthesis

I-Hielscher Ultrasonics ikhiqiza okokusebenza okuphezulu kwe-ultrasonic kokuhlanganiswa kwama-hydrogel. Kusuka kusayizi omncane naphakathi no-R&I-D kanye ne-pilot ultrasonicators ezinhlelweni zezimboni zokukhiqiza ezokuhweba nge-hydrogel ngemodi eqhubekayo, iHielscher Ultrasonics inezidingo zenqubo yakho ezihlanganisiwe
Ama-ultrasonicators ebanga lezimboni angaletha ama-amplitudes aphakeme kakhulu, avumela ukusabela okuthembekile kokuxhumanisa nokwenziwa kwamakhemikhali nokusabalalisa okufanayo kwezinhlayiya ze-nano. Amplitudes afika ku-200µm angaqhutshwa ngokuqhubekayo ngokuqhubekayo ekusebenzeni kwe-24/7/365. Ngama-amplitudes aphakeme kakhulu, ama-sonotrode e-ultrasonic akhethiwe ayatholakala.

Kungani i-Hielscher Ultrasonics?

  • ukusebenza kahle
  • Ubuchwepheshe besimanje
  • ukuthembeka & ukuqina
  • ibhethri & emugqeni
  • nganoma iyiphi ivolumu
  • isoftware ehlakaniphile
  • izici ezihlakaniphile (isb., ukuvumelanisa idatha)
  • I-CIP (ihlanzekile-endaweni)

Sibuze namhlanje imininingwane eyengeziwe yezobuchwepheshe, amanani entengo kanye nekhotheshini engabophezelekile. Abasebenzi bethu abanesikhathi eside benolwazi bayakujabulela ukukuthinta!
Ithebula elingezansi linikeza isibonakaliso somthamo wokucubungula we-ultrasonicators wethu:

Iqoqwana Ivolumu flow Rate Amadivayisi ezinconyiwe
1 kuya ku-500mL 10 kuya ku-200mL / min UP100H
10 kuya ku-2000mL 20 kuya ku-400mL / min UP200Ht, UP400St
0.1 kuya ku-20L 0.2 kuya ku-4L / min I-UIP2000hdT
10 kuya ku-100L 2 kuya ku-10L / iminithi I-UIP4000hdT
na 10 kuya ku-100L / iminithi UIP16000
na sikhulu yinhlanganisela UIP16000

Xhumana nathi! / Cela Us!

Cela ulwazi oluthe xaxa

Uyacelwa ukuthi usebenzise ifomu elingezansi ukucela ulwazi olungeziwe mayelana nezinhlelo zokusebenza ze-ultrasonic, izinhlelo zokusebenza nentengo. Sizokujabulela ukuxoxa ngenqubo yakho nawe futhi sikunikeze uhlelo lwe-ultrasonic oluhlangabezana nezidingo zakho!









Sicela uqaphele wethu Inqubomgomo yobumfihlo.


Ultrasonic high-shear homogenizers are used in lab, bench-top, pilot and industrial processing.

I-Hielscher Ultrasonics ikhiqiza ama-homogenizers asebenza ngokusebenza okuphezulu wokuxuba izinhlelo, ukusabalalisa, ukumisa nokukhipha ilebhu, umshayeli kanye nesikali sezimboni.

Izincwadi / Izikhombo



Amaqiniso Okufanele Ukwazi

Ama-Hydrogels asetshenziselwa ini?

Ama-Hydrogels asetshenziswa ezimbonini eziningi ezifana ne-pharma yokulethwa kwezidakamizwa (isb. Ukukhishwa kwesikhathi, ngomlomo, ngemithambo, ngezihloko noma ngokuletha izidakamizwa), umuthi (isb. Njengezikhafula ekwakhiweni kwezicubu, okufakelwa amabele, okokusebenza kwe-biomechanical, ukugqokwa kwamanxeba), izimonyo imikhiqizo, imikhiqizo yokunakekelwa (isib. amalensi oxhumana nabo, amanabukeni, napkin sanitary), ezolimo (isb. zokwenziwa kwezibulala-zinambuzane, ama-granules okubamba umswakama womhlabathi ezindaweni ezomile), ucwaningo lwezinto ezibonakalayo njengama-polymer asebenzayo (isib. isizukulwane), ukuchelela amalahle, iqhwa lokufakelwa, izithasiselo zokudla, neminye imikhiqizo (isib. iglu).

Ukuhlukaniswa kwama-Hydrogels

Lapho ukuhlukaniswa kwama-hydrogel kwenziwa ngokuya ngesakhiwo sawo kungahlukaniswa ngale ndlela elandelayo:

  • i-amorphous (non-crystalline)
  • i-semicrystalline: Ingxube eyinkimbinkimbi yezigaba ze-amorphous ne-crystalline
  • i-crystalline

Lapho igxile ekwakhiweni kwe-polymeric, ama-hydrogel nawo angahlukaniswa ngezigaba ezintathu ezilandelayo:

  • i-hydrogels ye-homopolymeric
  • i-copolymeric hydrogels
  • ama-hydrogel amaningi / ama-IPN hydrogels

Ngokuya ngohlobo lwe-crosslinking, ama-hydrogel ahlukaniswa abe:

  • amanethiwekhi axhumene namakhemikhali: izinhlanganisela ezihlala njalo
  • amanethiwekhi axhumeke ngokomzimba: izihlanganisi zesikhashana

Ukubukeka komzimba kuholela ekuhlukanisweni ku:

  • matrix
  • ifilimu
  • microsphere

Ukuhlukaniswa okususelwa kunethiwekhi kagesi:

  • i-nonionic (engathathi hlangothi)
  • ionic (kufaka phakathi i-anionic noma i-cationic)
  • i-amphoteric electrolyte (ampholytic)
  • i-zwitterionic (i-polybetaines)

Hielscher Ultrasonics supplies high-performance ultrasonic homogenizers from lab to industrial size.

Ukusebenza okuphezulu kwe-ultrasonics! Uhla lomkhiqizo kaHielscher lumboza isibonisi esigcwele kusuka ku-compact lab ultrasonicator ngaphezulu kwamayunithi ebhentshini-phezulu kuya ezinhlelweni ezigcwele zezimboni ze-ultrasonic.