Formulaciones u nano-THC solubles ichil ja' yéetel sonicación
Le formulación bebidas mejoradas yéetel THC jach jump'éel desafío. – Le bebidas yéetel infusión THC k'a'abéet u nanoemulsionadas utia'al u ts'aik jump'éel ka'anal biodisponibilidad yéetel, tune', potencia, estabilidad chowak plazo yéetel apariencia sáasil. Le nanoemulsificación ultrasónica ti' THC ti' a Jach ma'alob eficiente yéetel xoknáalo'obo', ku ts'aik bey resultado a THC superior.
THC nanoemulsionado tumen ultrasonidos
Con el Fin de Je'e túumben vías jant p'áatalij THC, u ti' aumento alternativas bey le bebidas enriquecidas yéetel THC yéetel le Janalbe'en. Le dispositivos emulsionantes ultrasónicos u utilizan utia'al u producir nanoemulsiones aptas uti'al alimentario, u etiqueta Cho' yéetel estables ichil ya'ab k'iin. Le emulsificación ultrasónica jach compatible yéetel estabilizantes grado alimentario (p'el. ej. Estuph nano-emulsionante), ku ti' paklan mentik nanoemulsiones transparentes u ka'anal calidad, estables chowak plazo yéetel yéetel juntúul biodisponibilidad extraordinariamente ka'anal. Le nanoemulsiones ultrasónicas suutikuba'ob le THC jump'éel mezcla nanomejorada soluble ja', u añadir u janalbe'eno'ob yéetel bebidas. Le emulsificación ultrasónica ma' interfiere yéetel le sabor yo'osal áantajil ti' u formulación.
Le ultrasonidos bin yano'ob sonda ku ts'áiko'ob nanoemulsiones u THC solubles te' ja' yéetel nanomejoradas yo'osal bebidas yéetel recetas Janalbe'en yéetel juntúul biodisponibilidad superior.
Ba'axten ka nanoemulsiones u THC.
Le nanoemulsiones THC ku emulsiones u k'aab tsaats ichil ja' (O leti' W) Buka'aj nanométrico, yaan jump'éel apariencia sáasil leti' transparente yéetel juntúul estabilidad in chowak plazo. Le THC jach jump'éel aceitoso compuesto ku, ti' circunstancias meyaj, ma' u xa'ak'pajal yéetel ja', ts'o'ok u le tsaats yéetel ja' ku rechazan paklan tsikbal. Le ultrasonicación proporciona jump'éel cizallamiento mecánico, u pa' le gotas u k'aab tsaats yéetel ja' tak chukpachtik jump'éel Buka'aj nanométrico. Debido a le Buka'aj le gotas ti' nanoescala, le nanoemulsiones yaan jump'éel bey transparente yéetel xane' yéetel le cinéticamente estables, ba'ax u k'áat u ya'al ti' le fases u k'aab tsaats yéetel ja' ma' u p'atikuba'ob. Le diminutas gotas le compuesto bioactivo aceitoso, es decir le THC, ku engullidas tumen gotas ja' jach mejen. Jump'éel emulsionante leti' surfactante áantaj tu le nanoemulsión bixake' estable in chowak plazo.
Le nanoemulsiones ultrasónicas ku ts'abal jump'éel biodisponibilidad superior, ba'ax k'a'ana'an utia'al u compuestos bioactivos bey le CBD, le THC, le vitaminas, le polifenoles, etcétera, u absorban plenamente yéetel comprendan u propiedades beneficiosas yo'osal ts'aak. Ti' le modo, le nanoemulsiones preparadas tumen ultrasonidos le ideales utia'al u formulaciones ti' le industria alimentaria, bebidas yéetel cosmética. Ti' le producir nanoemulsiones yéetel juntúul nuxi' biodisponibilidad, le nanoemulsificación ultrasónica u ti'al jump'éel láaka ch'a'abil ka fiable formular bebidas, Janalbe'en, suplementos dietéticos yéetel cosméticos ku ya'alik THC ma'alob biodisponible.
UP400St, jump'éel potente homogeneizador ultrasónico u 400 vatios, utia'al u producción bebidas u THC nanoemulsionadas.
Bix mentik nanoemulsiones THC transparentes yéetel solubles ti' ja' yo'osal sonicación
Le emulsionantes ultrasónicos le dispositivos fáciles ti' biilankiltej, ku ti' permiten formular u nanoemulsión tsaats ichil ja' THC. Dado ti' le ultrasonidos chéen aplican jump'éel cizallamiento mecánico ti' le mezcla je'ebix, THC ichil ja', le formulación resultante jach apta uti'al alimentario. Le sonicación jach compatible yéetel Óoli' je'el aj nu'uktaj emulsionante (xan k'ajóolta'an je'el bix estabilizador leti' surfactante). Le elección juntúul aj nu'uktaj emulsionante ye'esik uti'al alimentario (p'el. ej. Estuph nano-emulsionante) ti' ku yáantik mentik jump'éel elegante formulación nano-mejorada grado alimenticio yéetel u etiqueta Cho' u ku taasik THC ti' jump'éel bix ma'alob biodisponible.
Yaan u mentik jump'éel nanoemulsión ba'ax ku taasik tsaats THC, u componente le tsaats THC ku páajtal diluir ti' jump'éel tsaats portador, je'ebix, tsaats u yeek' cáñamo wa tsaats MCT. Tu continuación le fase oleosa ku emulsiona ti' le fase acuosa utilizando jump'éel ultrasonido bey le UP400St. Le sonicación proporciona jump'éel tuukula' nanoemulsificación séeba'an ka eficiente. Ka' jump'éel minutos le nanoemulsión tsaats ichil ja' transparente ka estable in chowak plazo u ts'o'ok.
Yéetel le ultrasonicación, le producción nanoemulsiones ch'a'abil jach.
- Nanoemulsiones transparentes yéetel ka'anal biodisponibilidad
- Séeba'an & Xoknáalo'obo'
- Estabilidad in chowak plazo
- Utia'al u industria alimentaria yéetel farmacéutica
- Yantio' & Chéen ch'a'abil u biilankiltej
Ultrasonidos u ka'anal rendimiento utia'al u nanoemulsiones THC
Hielscher Ultrasonics’ systems are reliable machines used in the pharmaceutical and supplement production to formulate high-quality supplement formulations, which range from nano-emulsions to liposomes, nanostructured lipid carriers, solid-lipid nanoparticles, and inclusions complexes that are loaded with vitamins, antioxidants, flavonoids, peptides, polyphenols and other bioactive compounds and provide highest bioavailability, great stability and functionality. For the nano-emulsification of THC into drinks, beverages, tinctures and supplements, Hielscher offers you powerful and reliable ultrasonicators at the size of your production requirements. To meet its customers’ demands, Hielscher supplies ultrasonicators from the compact hand-held lab homogenizer and bench-top ultrasonicators to fully industrial ultrasonic systems for the production of high-volumes of nootropics and smart drug formulations. Ultrasonic formulating processes can be run as batch or as continuous inline process using an ultrasonic flow-through reactor. A broad range of ultrasonic sonotrodes (probes) and reactor vessels are available to ensure an optimal setup for your liposome production. The robustness of Hielscher’s ultrasonic equipment allows for 24/7 operation at heavy duty and in demanding environments.
Le uláak' tabla ku ts'aik ti' jump'éel indicación le Buka'aj u ba'al u procesamiento aproximada u k ultrasonidos:
| Volumen lote | Gasto | Dispositivos recomendados |
|---|---|---|
| U 1 u 500 ml | U 10 ti' 200 ml leti' min | UP100H |
| U 10 ti' 2000 ml | Ti' 20 u 400 ml leti' min | UP200Ht, UP400St |
| 0. 1 u 20L | 0. 2 u 4L leti' min | UIP2000hdT |
| U 10 u 100L | U 2 u 10 l leti' min | UIP4000hdT |
| n.d. | U 10 ti' 100 L leti' min | UIP16000 |
| n.d. | Mayor | Racimo u UIP16000 |
Xook k! Leti' k'áatiko'ob k!
Homogeneizadores ultrasónicos u ka'anal potencia ti' laboratorio Utia'al piloto y industrial escama.
Bibliografía leti' Referencias
- Daniel G. Barrus, Kristen L. Capogrossi, Sheryl C. Cates, Camille K. Gourdet, Nicholas C. Peiper, Scott P. Novak, Timothy W. Lefever, Jenny L. Wiley (2016): Tasty THC: Promises and Challenges of Cannabis Edibles. Methods Rep RTI Press. Nov. 2016.
- Kentish, S.; Wooster, T.; Ashokkumar, M.; Simons, L. (2008): The use of ultrasonics for nanoemulsion preparation. Innovative Food Science Emerging Technologies 9(2):170-175.
- Campelo, Pedro Henrique; Junqueira, Luciana Affonso; de Resende, Jaime Vilela; Domingues Zacarias, Rosana; de Barros Fernandes, Regiane Victória; Alvarenga Botrel, Diego; Vilela Borges, Soraia (2017): Stability of lime essential oil emulsion prepared using biopolymers and ultrasound treatment. International Journal of Food Properties Vol.20, No.S1, 2017. 564-579.
- Maphosa, Yvonne; Jideani, Victoria A. (2018): Factors Affecting the Stability of Emulsions Stabilised by Biopolymers. In: Science and Technology Behind Nanoemulsions (Edited by Selcan Karakuş). 2018.
Datos u tojol le su'utalil K'ajóolt
CBD vs THC
Le género le páak'alo' Cannabis ku páajtal distinguir ti' paak'alo'ob cáñamo yéetel marihuana.
Cannabidiol (CBD) is found in hemp and marijuana plants, whilst the compounds tetrahydrocannabinol (THC) is exclusively present in marijuana plants. Tetrahydrocannabinol (THC) and cannabidiol (CBD) are the two most important cannabinoids of at least 113 cannabinoids identified in cannabis. THC is the principal psychoactive constituent of cannabis, chemically known as (−)-trans-Δ9-tetrahydrocannabinol. Per definition, hemp plants are cannabis plants that contain less than 0.3 percent THC, while marijuana plants are cannabis plants that contain higher concentrations of THC. Hemp is also grown as crop to produce industrial fibre. CBD, the main bioactive compound in hemp, is a non-psychoactive substance, which means CBD does not make you “Ka'anal”. CBD is commercially available in various forms such as tinctures, gels, gummies, oils, tablets, capsules, full spectrum extracts, topicals (creams, lotions, balms, oils and ointments) etc..
THC is the main psychoactive bioactive substance in marijuana which is responsible for the “Ka'anal” feeling of euphoria. THC can be ingested via smoking a “xíiw” joint or by consuming THC-enriched edibles, e.g. brownies. It’s also available in oils, tinctures, capsules, and other forms of administration.
Je'el compuestos le cannabis, le CBD yéetel le THC, ku unen ti' le yaan endocannabinoide ch'íijsajil, ba'ale' Amal compuesto yaan táanil jach jejeláas (je'ebix, ma' psicoactivo kíinsa'ab tu táan psicoactivo).
Both, CBD and THC are known as therapeutics, which are used as drug or medicinal supplement to cure or relieve several diseases and medical conditions. CBD is known for its anti-inflammatory and relaxing effects. That’s why it is used to as supplemental treatment to help with various conditions such as seizures, inflammation, pain, psychosis or mental disorders (e.g. OCD), inflammatory bowel syndrome (IBS), nausea, head aches and migraines, depression, and anxiety.
Le THC ku administra utia'al u aliviar afecciones ts'akankil bey k'i'inan, le espasmos musculares, le glaucoma, le insomnio, le si'ipil wi'ijlajken, le náuseas yéetel le ansiedad.