Extracción k'úuts ultrasónico

Le extracción convencional u k'úuts jach jump'éel tuukula' lento yéetel lento, u implica u búukinta'al disolventes tóxicos ti' altas temperaturas, ba'ax ku beetik u le tuukula' bixake' sajbe'en.

Le extracción asistida tumen ultrasonidos alcaloides le k'úuts u páajtal ejecutar yéetel ja' wa disolventes leves ti' jump'éel tuukula' séeba'an u jump'éel minutos. Le alcaloides extraídos tumen ultrasonidos, bey le nicotina le k'úuts, liberan ti' jump'éel procedimiento séeba'an yéetel ma'alob eficiente, u proporciona ka'anatako'ob rendimientos jump'éel extracto espectro k'iini' (ba'ax ku taasik nicotina, nornicotine, ácido clorogénico (ácido 5-caffeoylquinic), rutina, ácido cafeico yéetel escopoletina, solanesol, etc.).

Extracción Ultrasónica u k'úuts

Le extracción asistida tumen ultrasonidos (EAU) leti' jump'éel método u extracción séeba'an, xoknáalo'obo' yéetel conveniente, ku basa ti' le ka'anatako'ob ultrasonidos potencia. Le ondas ultrasónicas intensas generan jump'éel séeba'an micromovimiento yéetel cavitación acústica te' sistemas sólido-líquidos (je'ebix, xooko'obo' vegetal ti' disolvente ti', je'ebix, le' k'úuts ti' etanol), ku resulta ti' asab transferencia juuch', bey jump'éel tuukula' u extracción acelerado. Ti' comparación yéetel uláak' yo'osal avanzadas u extracción je'el bix le extracción fluidos supercríticos yéetel le extracción iones-par ti', le extracción asistida tumen ultrasonidos significativamente asab leti', respetuosa yéetel u ka'a ambiente, asab segura yéetel asab ch'a'abil u biilankiltej. Tune', le extracción ultrasónica u ti'al tu láaka extracción preferida liberar compuestos bioactivos le botánicos.
Le extracción ultrasónica ku ts'aik bey resultado jump'éel extracto amplio espectro, ba'ax ku taasik nicotina, lela' le alcaloide primario ti' le k'úuts yéetel 94-98 ti chúumuk le contenido total ti' alcaloides, bey le alcaloides nornicotine, anabasine, anatabina, cotinina yéetel miosmina.

Le extracción ultrasónica le ampliamente utilizada utia'al u producción extractos botánicos bey CBD cannabis yéetel cáñamo. Ultrasonidos Jach ma'alob eficiente yéetel séeba'an.

Extracción Ultrasónica u Botánicos bey CBD Cannabis

SonoStation u Hielscher Ultrasonics jach jump'éel configuración ultrasónica ch'a'abil u biilankiltej utia'al u escala producción. (Beetik clic utia'al waaj a kóochkinsike'ex!).

SonoStation – juntúul t.u.m ultrasónico yéetel 2 x Ultrasonidos 2kW, tanque jíita'al yéetel bomba – Jach juntúul t.u.m ch'a'abil u biilankiltej utia'al u extracción.

Solicitud a'alajil t'aan

Yanak ti' tu yilaje' k Política yojeta'al mixba'al.

Extractos k'úuts espectro k'iini' yéetel sonicación

Alcaloides bey le nicotina yéetel nornicotine, ácido clorogénico, fenólico, solanesol yéetel uláak' compuestos bioactivos táan u béeytal u aislados jáan, eficientes yéetel seguros yo'osal extracción ultrasónica. Le extracción convencional u k'úuts implica u búukinta'al disolventes tóxicos bey le heptano altas temperaturas, ku p'áatal le tuukula' extracción ti' jump'éel procedimiento sajbe'en. Tuláakal le tuukula' extracción convencional uk' aprox. 24 h yéetel tune' le jach lento.
Le extracción ultrasónica u páajtal u bey extracción ja' fría wa utilizando disolventes suaves bey etanol wa mezcla etanol yéetel ja' temperatura ambiente wa temperaturas ligeramente elevadas. Le sonicación ku káaltal jump'éel minutos, ku p'áatal le extracción ti' jump'éel procedimiento séeba'an. Ku ts'o'okole', u búukinta'al ja' wa disolventes suaves le tuukula' le completamente seguro ka conveniente.

Le' k'úuts ultrasónicamente desfavorecidas u p'atikuba'ob le compuestos extraídos ti' le disolvente.

The ultrasonically produced full spectrum extracts contain the primary alkaloid nicotine as well as the secondary or minor alkaloids such as anabasine or 3-(2-piperidinyl)pyridine, anatabine or 3-(2-1,2,3,6-tetrahydropyridyl)pyridine, cotinine or 1-methyl-5-(3-pyridyl)-2-pyrrolidinone), 2,3’-dipyridyl or isonicoteine, N-formylnornicotine or 2-(3-pyridyl)pyrrolidinecarbaldehyde, myosmine or 3-(1-pyrrolin-2-yl)pyridine, nornicotine or 3-(pyrrolidin-2-yl)pyridine, and beta-nicotyrine or 3-(1-methylpyrrol-2-yl)pyridine.

The content of these alkaloids varies depending on tobacco species and tobacco products. While nicotine is the primary alkaloid with 94–98% of the total alkaloid content, nornicotine and anatabine are the two most abundant secondary alkaloids, each accounting for approx. 2% to 6% of the total alkaloid content of tobacco.

Benefits of Ultrasonic Tobacco Extraction:

  • asab rendimiento
  • ka'anal calidad
  • extracción rápida
  • Tuukula' leve yéetel ma' térmico
  • Ja' wa disolvente
  • Simple & meyajo'ob segura
Ultrasonic tobacco extraction with the ultrasonicator UP400St (400W) and the probe S24d20L2 for higher nicotine yields in shorter processing time. Ultrasonic tobacco extraction can be run with mild solvents and is thereby an green, environmental-friendly method.

Ultrasonic extractor UP400ST for the extraction of nicotine from tobacco leaves

Choose from a Broad Selection of Solvents

Using ultrasonic extraction, you can select from various solvents, including water, alcohol, ethanol, methanol, ethanol-water mixtures or strong solvents such as heptane or hexane. All of the former named solvents have been already successfully tested and shown to be effective for the isolation of bioactive compounds such as alkaloids, terpenoids, phenolics and solanesol from tobacco plant materials. Sonication can be used in solvent-free cold-water extraction (e.g. to prepare organic extracts) or can be combined with a solvent of your choice.
Kaan asab yóok'ol le disolventes utia'al u extracción ultrasónica u yik'áalil botánicos!

Hielscher ultrasonicator UP400St with sonotrode S24d22L2 for extraction of nicotine and harmala from tobacco leaves.

Procesador ultrasónico UP400St (400 vatios). for the extraction of alkaloids such as nicotine and harmala from tobacco leaves.

Extractores ultrasonido ka'anal rendimiento

Procesador ultrasónico UIP4000hdT (4kW) utia'al u extracción pectinas ti' jump'éel tuukula' industrial ti' internet ichil.Hielscher’s ultrasonic equipment is a commonly extraction tool for the isolation of bioactive compounds from botanicals. Supplying ultrasonic extractors for all process scales, Hielscher is able to recommend you the most suitable ultrasonic system for your needs. Starting with compact, yet powerful Sistemas laboratorio for analysis and feasibility testing, Hielscher offers the full range from lab and pilot plant ultrasonicators up to ultrasonido jaatsatako'ob industrial reactors. Offering the full band width of ultrasonic processors, Hielscher has the ideal setup for your extraction process. Depending on your process volume and goal, ultrasonic extraction can be performed in batch or continuous flow mode. Manifold accessories such as sonotrodes, booster horns, flow cells and reactors allow to equip the ultrasonic processor to fulfil the process targets ideally.
Hielscher’s ultrasonic processors can be precisely controlled and process data are automatically recorded on the integrated SD-card of our digital ultrasonic systems. The reliable control over the process parameters ensure a consistently high product quality. The automatic data recording of the process parameters allow for an easy process standardization and the fulfilment of Good Manufacturing Practices (GMP).
Robustez le nu'ukulil ultrasónico u Hielscher ku cha'antik jump'éel funcionamiento 24 leti' 7 ti' condiciones pesadas yéetel tu entornos exigentes. Operación ch'a'abil ka segura, bey le t'okik mantenimiento ku betiko'ob le kaambalilo'ob ultrasónicos u Hielscher le tsíimino' meyaj confiable ti' u producción.

Le uláak' tabla ku ts'aik ti' jump'éel indicación le Buka'aj u ba'al u procesamiento u aproximado k ultrasonicators:

Volumen lote Tasa flujo Dispositivos recomendados
0.5 u 1.5mL N.a. VialTweeter
1 u 500mL 10 200 mL leti' min UP100H
10 u 2000mL 20 400 mL leti' min. UP200Ht, UP400St
0.1 ti' 20L 0.2 u 4 L leti' min UIP2000hdT
10 ti' 100L 2 10 L leti' min UIP4000
N.a. 10 100 L leti' min UIP16000
N.a. asab nojoch Cluster u UIP16000

Contactar k bejla'e' utia'al a wojeltik! K máaxo'ob ku ma'alob kanasaj yéetel encantado u discutir u tuukula' u extracción yéetel tech!

Ti' máax ku yéetel to'on! Leti' k'áatiko'ob k!

Solicitar a wojeltik

Béet meyaj le uláak' formulario, wa k'áato' solicitar a'alajil t'aan adicional yo'osal homogeneización ultrasónica. Yaan k encantados u ofrecer juntúul t.u.m ultrasónico u satisfacer le requerimientos.

Yanak ti' tu yilaje' k Política yojeta'al mixba'al.

Hielscher Ultrasonidos fabrica ultrasonicadores ka'anal rendimiento utia'al u aplicaciones sonoquímicas.

Procesadores ultrasónicos u ka'anal potencia tak laboratorio tak le escala piloto yéetel industrial.

Le ultrasonicador industrial UIP2000hdT ti' jump'éel stand yaabilajech

UIP2000hdT, a 2kW powerful high-performance ultrasonicator

Hechos u tojol le su'utalil K'ajóolt

Why is Ultrasonic Extraction so Effective?

Ultrasonically-assisted extraction (UAE) is based on coupling highly intense ultrasound waves (acoustic waves) into a liquid or slurry. The acoustic waves create alternating high pressure / low pressure cycles, which result in the phenomenon of acoustic cavitation. The phenomenon of ultrasonic or acoustic cavitation is characterized by extreme, locally confined conditions of very high pressures, temperatures and shear forces. In proximity of the imploding cavitation bubbles, temperatures of up to 5000K, pressures of 1000 atmosphere, heating-cooling rate above 1010 K/s and liquids jets with up to 280m/s velocity, which appear as very high shear force and turbulences in the cavitational zone, can be measured. The combination of these factors (pressure, heat, shear and turbulence) disrupt cells (lysis) and intensify mass transfer during the extraction process. Thereby, the liquid-solid extraction of phytoconstituents from plant cells is promoted. The ultrasonic extraction technique is widely applied for the successful and efficient extraction of flavonoids, polysaccharides, alkaloids, phytosterols, polyphenols, and pigments from plants.

Le disruptores ultrasónicos u utilizan utia'al u extracciones fuentes fito (tumen ejemplo, paak'alo'ob, algas, hongos).

Extracción ultrasónica u células vegetales: le sección transversal microscópica (TS) ye'esik meyaj meyajo'ob ichil le extracción ultrasónica ti' células (magnificación 2000 x) [recurso: Vilkhu et el. 2011]


Various plants in the Nicotiana genus and the Solanaceae (nightshade) family are known as tobacco plants. Besides being the commonly used term for the plant, tobacco describes also the products prepared from the cured leaves of the tobacco plant. Whilst Nicotiana tabacum is the main crop use for tobacco and nicotine production, there are over 70 plant species of tobacco. N. tabacum is the dominant species used for tobacco products, however the more potent variant N. rustica can be found around the world and is used for.
Tobacco contains the stimulant alkaloid nicotine as well as harmala alkaloids. Dried and cured tobacco leaves are mainly used for smoking in cigarettes, cigars, pipes, shishas as well as e-cigarettes, e-cigars, e-pipes and vaporizers. Alternatively, they can be consumed as snuff, chewing tobacco, dipping tobacco and snus.

The tobacco plant family contains various (sub-)species, which exhibit different alkaloid and flavour profiles.
Oriental tobacco (Nicotiana tabacum L.) is a species of tobacco grown mainly in Turkey, Greece, and neighboring areas, which is used for the commercial production of cigarettes, cigars and chewing tobacco. It has a strong characteristic flavor, is relatively low in nicotine and high in reducing sugars, acids, and volatile flavor oil, which gives the tobacco products an intense aroma.

There are 67 natural species of tobacco known. Below the most common species are listed:

  • Nicotiana acuminata (Graham) Hook. – manyflower tobacco
  • Nicotiana africana Merxm.
  • Nicotiana alata Link & Otto – winged tobacco, jasmine tobacco, tanbaku (Persian)
  • Nicotiana attenuata Torrey ex S. Watson – coyote tobacco
  • Nicotiana benthamiana Domin
  • Nicotiana clevelandii A. Gray
  • Nicotiana glauca Graham – tree tobacco, Brazilian tree tobacco, shrub tobacco, mustard tree
  • Nicotiana glutinosa L.
  • Nicotiana langsdorffii Weinm.
  • Nicotiana longiflora Cav.
  • Nicotiana occidentalis H.-M. Wheeler
  • Nicotiana obtusifolia M. Martens & Galeotti – desert tobacco, punche,tabaquillo
  • Nicotiana otophora Griseb.
  • Nicotiana plumbaginifolia Viv.
  • Nicotiana quadrivalvis Pursh
  • Nicotiana rustica L. – Aztec tobacco, mapacho
  • Nicotiana suaveolens Lehm. – Australian tobacco
  • Nicotiana sylvestris Speg. & Comes – South American tobacco, woodland tobacco
  • Nicotiana tabacum L. – commercial tobacco grown for the production of cigarettes, cigars, chewing tobacco, etc.
  • Nicotiana tomentosiformis Goodsp.

The three species below are man-made hybrids:

  • Nicotiana × didepta N. debneyi × N. tabacum
  • Nicotiana × digluta N. glutinosa × N. tabacum
  • Nicotiana × sanderae Hort. ex Wats. N. alata × N. forgetiana

Types of Tobacco
The curing and subsequent aging process of tobacco leaves induces a slow oxidation and degradation of the present carotenoids in tobacco leaf. Due to the oxidation, certain compounds in the tobacco leaves are synthesized, which result in sweet hay, tea, rose oil, or fruity aromatic flavors, which contribute to thesmoothnessof the smoke. Starches are converted into sugars, which subsequently glycate proteins, and are oxidized into advanced glycation endproducts (AGEs). This is a caramelization process that also gives the smoke its flavor.
The preparation and curing method of tobacco influences its final aroma characteristics. Curing can be achieved by air-, fire-, flue-, and sun-curing. For example, flue-cured tobacco (e.g. from France) contains only low levels of alkaloids, whilst air-cured Burley tobacco (e.g. sourced from Guatemala) is known for its high content of alkaloids.