Ultrasonic Decarboxylation ʻo Cannabinoids

Decarboxylated cannabinoids hange ko e FBD, THC mo e FBG ʻi ha niʻihi tokolahi kehe ʻoku ʻiloa ko e foomu malohi, ʻa ia ʻoku ne fakahaaʻi ha ngaahi ola malohi mo ola lelei ange ʻi he sino ʻo e tangata (hange ko endocannbinoid System). Ko e Ultrasonication ko ha founga lelei ʻaupito ia ke toʻo ʻaki ha decarboxylate cannabinoids (e.g., FBDA, THCA, FBGA) ki heʻenau biologically ngaahi foomu malohi ange (e.g., FBD, THC, FBG).

Decarboxylate Cannabinoids mo Sonication

Cannabinoids such as CBD, THC, CBG etc. are extracted and decarboxylated by ultrasonication. ʻOku ʻiloa ʻa e FBD ʻi hono fakatupulaki e moʻui lelei mo e ngaahi ola fakafaitoʻo. Ka ʻi he ongo faʻahinga cannabis fakatouʻosi, ʻi he hemp mo e maliuana, ʻoku maʻu pe ʻa e ʻesiti cannabidiolic (FBDA) ʻi he lolotonga cannabidiol (FBD) ʻoku ʻi he kiʻi lahi siʻisiʻi pe.
Ko e ha hono faikehekehe ʻo e FBD mo e FBDA?
Ko e FBDA ko e fakaʻilonga ia ʻo e FBD pea ʻoku ʻi ai ha kulupu ʻesiti ʻoku fakapipiki ki he FBD molecule, ko ha kulupu carboxyl ʻoku ui ko e. ʻOku fakatou hoko ʻa e FBD mo e FBDA, ko ha ngaahi meʻa ʻoku ʻikai kona, ʻikai psycho, ʻa ia ko hono ʻuhinga ʻoku ʻikai ke nau ʻomi ha ola "maʻolunga". Ka ʻoku kehekehe ʻaupito ʻa e ngaahi ola bioactive ʻo e FBD mo e FBDA. ʻOku ʻikai ke ʻi ai ha faʻahi ʻa e FBDA, pea ʻoku mahuʻinga ʻaupito ia ki he fotunga maʻulalo, lolotonga ia – ʻi he taimi decarboxylated ai ki he FBD – ʻOku hanga ʻe he FBD molecules ʻo fakalahi ʻenau ngaahi ola bioactive moʻui lelei kakato ko ha fakalahi ki he meʻakai fakafaitoʻo mo e meʻakai.
ʻOku uesia ʻe he decarboxylation ʻa e ngaahi foomu cannabinoid kehe kotoa pe hange ko e THCA, FBGA mo e niʻihi kehe foki. ʻOku toʻo ʻa e kulupu carboxyl koeʻuhi ke maʻu ʻa e ngaahi foomu ngaue, hange ko e, e.g., FBD, ∆⁹-THC (THC), FBG.
ʻOku liliu ʻe fakaʻata decarboxylation ʻa e foomu mamalohi ki he foomu cannabinoid malohi ange ʻaki hono toʻo ʻa e kulupu carboxyl ʻo fakafou ʻi ha ngaahi peau lalahi fakaʻata.

Ultrasonic Cannabinoid Decarboxylation

Ko e Decarboxylation (decarbing) ko ha sitepu angamaheni ia ʻi cannabis ngaue. ʻI he founga decarbing angamaheni, ʻoku fakaʻaongaʻi ai ʻe he kau pule ʻa e vela momoa ki he ngaahi konga ʻakau foʻou kae lava ke fakaului ʻa e FBDA ki he FBD, ∆9-THC-ʻesiti (THCA) ki he ∆9-THC (THC), FBGA ki he FBG etc. Ko ha sitepu ngāue makehe ʻeni kimuʻa pea toʻo e ʻulí pea ʻoku fie maʻu ki ai ha taimi mo ha ivi.
Ultrasonic decarboxylation maʻolunga ange ia ʻi he decarboxylation angamaheni ʻaki ha ngaahi lelei kehekehe. ʻUluaki, ʻoku ʻikai ko ultrasonic decarboxylation ko ha sitepu makehe ia, ka ʻoku hoko ia ʻi he taimi ʻoku maʻu ai cannabinoids ʻo fakafou ʻi ultrasonication mei hemp pe maliuana. Ko ultrasonic cannabis faitoʻo ko e founga maʻolunga ange ia ki hoko toʻo ʻuli mo decarboxylation ʻo phytocannabinoids. ʻOku maʻolunga ange ʻa e founga ultrasonic ʻi he toʻo ʻuli maʻolunga mo decarboxylation ʻa e mafana ʻo e ʻea mo e taimi nounou ke fai ai ha faitoʻo. ʻOku taʻofi heni ʻa e phytocannabinnoids ki he decomposition: ʻi ultrasonically decarboxylated cannabinoid, ʻoku ʻikai maʻu ha cannbinol (FBN). ko e cannabinol ko ha oxidation angamaheni ia ʻi he koloa pea ʻoku fakaʻilongaʻi ai ʻa e tuʻunga lelei. ʻOku ʻuhinga ʻeni ultrasonic decarbing ngaahi ola ʻi ha cannabis lelei.
ʻIkai ngata ai, ʻoku repeatable kakato mo reproducible ʻa e ngaahi ola ultrasonically kotoa pe ʻoku maʻu. Ko e taimi ʻoku mapuleʻingofua ai ʻa e ngaahi fakangatangata ultrasonic kotoa pe, ʻe lava ke toe hiki ʻa e ngaahi ola toʻo hingoa mo decarboxylation ʻaki ʻa e ala falalaʻanga. ʻOku malava heni ke fakapapauʻi ʻe he kau pule ʻa ʻenau founga ngaue mo ʻoange ki heʻenau kau fakatau cannabis ha ngaahi meʻa ʻoku hokohoko maʻolunga taha.

Ultrasonication is used to decarboxylate acidic cannabinoids (CBDA, THCA, CBGA) into their active forms such as CBD, THC and CBG.

E ultrasonicator UP400St ʻe lava ke fakaʻaongaʻi ki hoko decarboxylation mo hono toʻo e ʻuli ʻo e cannabinoids mei cannabis Sativa L.

Kole 'a e fakamatala




Fakatokanga'i ange 'etau Tu'utu'uni totonu fakatautaha.


Ngaahi lelei ʻo ultrasonic Decarboxylation

  • Hoko toʻo e ʻuli mo e decarboxylation
  • Founga 'o e vaivai, 'ikai-thermal
  • Faitoʻo vave
  • ʻIkai ha decomposition ʻo cannabinoids
  • Repeatability, reproducibility
  • Faingofua mo malu ke ngaue
  • ʻAta ki ha faʻahinga tohi pe
  • Tuʻunga lelei ʻo e koloa Standarized

Founga ke Decarb Cannabinoids ʻe Sonication

Te Sonication lava ʻo liliu ʻa e ʻesiti cannabinoids hange ko e FBDA, ∆9-THC-ʻesiti/TCA, FBGA mo e ala meʻa pehe. ki he ngaahi foomu bioactive ʻo e FBD, ∆9-THC, FBG etc. Ke maʻu ha decarboxylation ʻo fakafou ʻi ultrasonication, ʻoku fakatahaʻi leva ʻa e faitoʻo fakaʻata mo e faitoʻo vela. ʻOku ʻiloa ʻeni ko fakapapauʻi-sonication. ʻOku maʻu ʻa e tokolahi ʻo e FBD, ∆9-THC, mo e FBG ʻi he 110 ° c.

Cannabinoids mo honau ngaahi nunuʻa ʻi he sino ʻo e tangata

ʻOku koloaʻia ʻa e Cannabis Sativa L. ʻakau ʻi ha faʻahinga ʻe 113 tupu cannabinoids. Hange ko ʻeni, ko e FBD, FBDA, THC, THCA, FBG mo e FBGA ʻi he niʻihi kehe ʻoku cannabinoids (ʻoku toe ui foki ko e phytocannabinoids) ʻoku maʻu ʻi he fuʻu ʻakau cannabis. ʻOku toe maʻu foki Cannabinoids ʻi he sino ʻo e tangata, ʻa ia ʻoku nau ngaue ai ko signalling molecules ʻi he polokalama endocrine. ʻOku ʻiloa ʻa cannabinoids ʻoku faʻu ʻe he sino ʻo e tangata ko endocannabinoids. Endocannabinoids hoko ko ha neurotransmitters ʻoku haʻi ki cannabinoid meʻa puke. ʻOku ui ʻa e founga totonu ʻo e endocannabinoids mo cannabinoid meʻa puke ko e polokalama endocannabinnoid pea ʻoku ne fakahoko ha konga mahuʻinga ʻi he ngaahi tuʻutuʻuni ʻo e ngaahi fatongia fakaesino.
ʻI he lava ko ia ke uafu ʻa e cannabinoids ki he cannabinoid ʻa e tangata meʻa puke, cannabinoids ʻoku fakahoko ia ko ha faitoʻo fakafaitoʻo/fakafaitoʻo pea mo ha fakalahi ki he meʻakai fakatupu moʻui lelei.

UIP2000hdT for decarboxylation of cannabinoids from Cannabis Sativa L.

UIP2000hdT ki he decarboxylation ʻo e ʻesiti cannabinoids (e.g. cannabinoidic ʻesiti BDA) ki he cannabidiol malohi (FBD)

Ultrasonic Extractors for Cannabinoid Decarboxylation

Ko ultrasonic toʻo hingoa mo e decarboxylation ko ha tekinolosia ngaue falalaʻanga, ʻa ia ʻoku ne fakafaingofuaʻi mo fakavaveʻi ange ʻa hono ngaohi ʻo e ngaahi meʻa lelei cannabinoid mei he Cannabis Sativa L. ʻakau (hemp mo e maliuana). ʻOku ʻufiʻufi ʻe Hielscher Ultrasonics lekooti ʻa e ngaahi meʻa kotoa mei he fale fakatotolo fakakemi ultrasonicators ki he ngaahi founga toʻo hingoa lalahi. ʻI heʻene pehee, te tau lava ai ʻi Hielscher ʻo ʻoatu ʻa e ultrasonicator feʻunga taha ki hoʻo founga ngaue envisaged. ʻE tokoniʻi koe ʻe heʻetau kau ngaue taimi loloa mei feasibility ngaahi sivi mo e founga ngaue optimisation ki hono fokotuʻu hoʻo polokalama ultrasonic ʻi he tuʻunga fakaʻosi.
ʻOku hanga ʻe he kiʻi paaki fute siʻisiʻi ʻo ʻetau ultrasonic extractors pea pehe ki heʻenau versatility ʻi he ngaahi fili ki hono fola, ʻo ʻai ke nau feʻunga mo ha feituʻu fakangatangata pe ʻo cannabis ngaue ki he ngaahi fale. ʻOku fokotuʻu ʻa ultrasonic processors ʻi he funga ʻo e mamani ʻi he meʻakai, pharma mo hono fakalahi atu ki he ngaahi fale.

Founga toʻo hingoa mo e Decarboxylation systems

ʻOku ʻufiʻufi ʻe Hielscher Ultrasonics e koloa lekooti ʻa e ngaahi ngaue maʻolunga kotoa pe ultrasonicator ki hono toʻo e ʻuli mo e decarboxylation mei he siʻisiʻi ki he meʻafua lahi. ʻOku fakaʻata ʻe he ngaahi naunau kehe ki he fakatahaʻanga faingofua taha ʻo e ultrasonic device ʻoku feʻunga mo hoʻo cannabis toʻo ʻuli/decarboxylation. ʻOku makatuʻunga ʻa e tokolahi lelei ultrasonic fokotuʻutuʻu ʻi he tuʻunga envisaged, voliume, naunau totongi, kulupu (batch) pe laine ʻo e laine mo e fakahokohoko.

Kulupu (batch) mo e Tuhituhi

ʻE lava ke fakaʻaongaʻi ʻa e Hielscher ultrasonicators ki he kulupu (batch) mo e hokohoko atu ʻo e ngaue. ʻOku feʻunga ʻa e kulupu (batch) ultrasonic ki hono siviʻi ʻo e founga ngaue, optimisation mo e siʻisiʻi ki he tuʻunga ʻo e ngaohiʻanga koloa. Ultrasonic decarboxylation ʻo e ʻesiti phyto-cannabinoids (eg., FBDA, THCA, FBGA) ʻe lava ke hoko ʻi ha ava pe tapuni ultrasonic beaker pea pehe ki ha faitoʻo hokohoko ʻo fakaʻaongaʻi ha ultrasonic toʻotoʻo Seinopolo.. ʻOku maʻu ʻe Hielscher Ultrasonics ʻa e toʻo hingoa lelei taha mo decarboxylation fokotuʻutuʻu ki hoʻo tohi cannabis mo e ngaahi taumuʻa ki hono fakahoko.

Ultrasonic extractors ki he meʻa kotoa pe ʻe malava

UIP4000hdT fehufaki to'oto'o ki he sonication 'i he ngaue 'a e me'afuaʻOku ʻufiʻufi ʻe Hielscher Ultrasonics ʻa e tuʻunga kakato ʻo ultrasonic processors mei he loki fakatotolo fakakemi ultrasonicators ʻi he ngaahi founga ʻa e sea ki ʻolunga mo e pailate ki he ngaahi ultrasonic processors mo e malava ko ia ke ngaue fonu fonu loli ʻenau he houa. ʻOku fakaʻata kitautolu ʻe he koloa kakato ke tau ʻoatu ʻa e meʻa toʻo ʻuli ultrasonic/decarboxylator ki hoʻo naunau cannabis, founga ngaue mo e ngaahi taketi.
ʻOku lelei ʻa e ngaahi polokalama ultrasonic benchtop ki feasibility ngaahi sivi mo e founga ngaue optimization. ʻOku hanga ʻe he meʻafua ʻo e telinga ʻo makatuʻunga ʻi he ngaahi fakangatangata kuo fokotuʻu ʻo ʻai ke faingofua ʻaupito hono fakatupulaki ʻo e ngaue mei he fanga kiʻi meʻa iiki ange ki he faiva fakakomesiale kakato. ʻE lava ke fai ʻa e Scaling ʻaki hano fola ha ʻiuniti malohi ange ultrasonic pe clustering ha ultrasonicators ʻoku faitatau mo ia. ʻI he UIP16000,000, ʻoku ʻomi ai ʻe Hielscher ʻa e misini toʻo ʻuli malohi taha ultrasonic fakaemamani lahi.

Ko hono mapuleʻi Amplitudes ki he ngaahi ola lelei

Ko e ultrasonicators Hielscher kotoa pe ʻoku mapuleʻingofua pea ʻoku ʻi ai ha fanga hoosi ngaue falalaʻanga. Ko e amplitude ko e taha ia ʻo e ngaahi fakangatangata mahuʻinga ʻoku ne takiekina ʻa e lavameʻa mo e ola lelei ʻo ultrasonic toʻo ʻuli ʻo Cannabis Sativa L. mo e hoko decarboxylation ʻo e cannabinoids.
Hielscher's industrial processors of the hdT series can be comfortable and user-friendly operated via browser remote control.Hielscher ultrasonics kotoa pe’ processors fakaʻata ʻa e tuʻunga totonu ʻo e amplitude. Ko e Sonotrodes mo e meʻatui ʻoku ʻikai ke ʻi ai ha ngaahi naunau ia ʻoku ne fakaʻata ke liliu ʻa e amplitude ʻi ha ngaahi meʻa lahi ange. ʻE lava ʻe he ultrasonic processors ʻa Hielscher ʻo fakahaofi ha amplitudes maʻolunga ʻaupito pea ʻave ʻa e malohi ultrasonic ʻoku fie maʻu ki hono fakaʻaongaʻi. Amplitudes ʻo aʻu ki 200μm ʻe faingofua pe ke lele hokohoko ʻi he tafa 24/7.
ʻOku ʻoatu ʻe he ngaahi feituʻu amplitude totonu mo hono vakaiʻi maʻu pe ʻo e ngaahi fakangatangata ʻo e founga ngaue ultrasonic ʻo fakafou ʻi he polokalama smart Software ʻa e malava ko ia ke ke tokangaʻi hoʻo naunau cannabis ʻaki ʻa e ngaahi tuʻunga lelei taha ultrasonic. Tokolahi lelei sonication ki he toʻo hingoa lelei taha mo e ngaahi ola decarboxylation!
ʻOku fakaʻata ʻe he robustness ʻo e meʻangaue ultrasonic ʻa Hielscher ʻa e ngaue ʻe 24/7 ʻi he fatongia mamafa pea mo e ngaahi ʻatakai ʻoku femoʻuekina. ʻOku hoko heni ʻa e meʻangaue ultrasonic ʻa Hielscher ko ha meʻangaue falalaʻanga ʻoku ne fulfils hoʻo ngaahi fie maʻu toʻo hingoa.

Faingofua, Siviʻi ke Fakatuʻutamaki

ʻE lava ke hoko ʻa e ngaahi founga ultrasonic ko ha telinga kaka kakato. ʻOku ʻuhinga ʻeni ko e ola kotoa pe kuo ke aʻusia ʻi hono fakaʻaongaʻi ha fale fakatotolo fakakemi pe ultrasonicator ʻi ʻolunga, ʻe lava ke kaka ia ki he Output tatau pe ʻo fakaʻaongaʻi ʻa e ngaahi fakangatangata tatau. ʻOku ngaohi ʻe he meʻa ni ultrasonication lelei ki hono siviʻi taʻetotongi feasibility, founga optimization pea toki fakahoko ki he ngaohiʻanga fakakomesiale. Fetuʻutaki mai ke tau ʻilo e founga ʻe lava ai ʻe sonication ʻo fakatupulaki hoʻo cannabis toʻo e polokalama.

ʻulungaanga maʻolunga taha – Faʻu mo Manufactured ʻi Siamane

ʻI he hoko ʻa Hielscher ko ha pisinisi ʻa e famili mo e fakalele fakafamili, ʻoku ne fakamuʻomuʻa ʻa e ngaahi tuʻunga moʻui lelei taha ki hono ultrasonic processors. ʻOku fokotuʻutuʻu ʻa e ultrasonicators kotoa pe, manufactured mo siviʻi fakaʻauliliki ʻi homau ʻuluʻi ʻofisi ʻi Teltow ofi ki Pealini ʻi Siamane. ʻOku hanga ʻe he Robustness mo e ala falalaʻanga ʻo e meʻangaue ultrasonic ʻa Hielscher ʻo ʻai ke hoko ia ko ha hoosi ngaue ʻi hoʻo faiva. 24/7 ngaue ʻi he uta kakato pea ʻi he ngaahi ʻatakai ʻoku femoʻuekina, ko ha ʻulungaanga fakanatula ia ʻo e ultrasonicators ngaue maʻolunga ʻa Hielscher.

'Oku 'omi 'e he e tepile 'i lalo ha faka'ilonga ia 'o e tu'unga 'o e ngaue ki he fakafuofua'i 'o e hotau ultrasonicators:

Kulupu (batch) 'o e tohi 'Oku tafe mai 'a e 'ea 'Oku fokotu'u atu 'a e ngaahi me'angaue
mL 'o e 1 ki he 500 10 ki he 200mL/miniti 'e UP100H
mL 'i he 10 ki he 2000 20 ki he 400mL/miniti 'e UP200Ht, UP400St
0.1 ki he 20L 0.2 ke 4L/miniti 'e UIP2000hdT
10 ki he 100L 2 ki he 10L/miniti 'e UIP4000hdT
n.a. 10 ki he 100L/miniti 'e UIP16000
n.a. lalahi fakataha'i 'o e UIP16000

Fetu'utaki mai kiate kimautolu! / Kole kiate kitautolu!

Kole ki ha fakamatala lahi ange

Kataki 'o ngaue 'aki e foomu 'i lalo ke kole ha toe fakamatala ki he ultrasonic processors, faka'aonga'i mo e totongi. Te mau fiefia ke alea'i e founga 'oku mo 'i ai mo ho'omou ngaahi fie ma'u ultrasonic he polokalama!









Kataki 'o fakatokanga'i ange 'etau Tu'utu'uni totonu fakatautaha.


Ultrasonic high-shear homogenizers are used in lab, bench-top, pilot and industrial processing.

Hielscher Ultrasonics ʻa e ngaohiʻanga koloa maʻolunga ultrasonic homogenizers ki hono tuifio ʻo e ngaahi polokalama, fakamovetevetea, emulsification mo e toʻo hingoa ʻi he fale fakatotolo fakakemi, pailate mo e meʻafua ki he ngaahi meʻa fakapisinisi.



Ngaahi mo'oni'i me'a 'oku mahu'inga ke 'ilo'i

Ko e ha Decarboxylate Cannabinoids?

Ko e Decarboxylation ko ha kemikale ia ʻoku ʻiloa ko ha seini kemikale ʻoku ʻiloa ko carboxyl kulupu mei ha molecule. ʻI he fuʻu ʻakau cannabis, ko e konga lahi ʻo e cannabinoids ʻoku ʻi heʻenau foomu ʻesiti hange ko e FBDA, THCA, FBGA mo e ala meʻa pehe. ʻOku ʻi ai ha kulupu carboxyl ʻi he ngaahi foomu ʻesiti pea ʻoku nau ʻiloʻi ko ha foomu mamalohi. Ko e ngaahi foomu ʻesiti ko ia ko e precursors ia ki he ngaahi foomu cannabinoid malohi ange (e.g. FBD, ∆⁹-THC, FBG etc.). Ki he pharmaceuticals, fakafaitoʻo mo e moʻui lelei, ko e decarboxylated, mo e founga malohi ange ʻo e cannabinoids ko ha ngaahi ʻuhinga mahino ia ʻoku fie maʻu.
Ko ia ai, ʻoku toʻo ʻa e kulupu carboxyl ʻesiti mei he cannabinoids ʻi ha founga ʻoku ui ko e "decarboxylation".
Hange ko ʻeni, ʻe lava ke decarboxylated ʻa e cannabis (colloquially foki "decarbed") ʻaki hono fakaʻaongaʻi e vela momoa. ʻOku toe hoko foki ʻa e Decarboxylation ʻi he taimi ʻoku tuku ai cannabis ke faitoʻo. Lolotonga e moʻui, ʻoku malolo mamalie hifo ʻa e seini carboxyl, ʻa ia ko ha founga ʻoku fuʻu lahi hono taimi. ʻI he taimi ʻoku hoko ai ʻeni, ʻoku mole ʻa e acidity mo e ʻesiti kehe cannabinoids. ʻo fakaʻau ke malohi ange ai. ʻE lava ke fakavaveʻi e Decarboxylation ʻe ha ngaahi founga kehe, hange ko fakapaaki ʻo-sonication.

Ko e ha hono lahi ʻo e Cannabinoids ʻi heʻeku Cannabis toʻo?

ʻOku fakafalala lahi ʻa e tokanga ʻa e cannabinoids ʻi ha konga naʻe toʻo ʻi he faʻahinga ʻakau (cannabis faingataʻaʻia), founga toʻo ʻuli pea tatau ai pe pe kuo decarboxylated ʻa e fuʻu ʻakau pe ʻikai.