Hielscher faka'ata tekinolosia

Faka'ata'ata Nano-Emulsions 'aki 'a e filosefa Ph mo e Ultrasonics

Fakamahino'i nano-emulsions 'oku 'i ai ha ngaahi polokalama lahi kehekehe 'i he me'akai, kia, mo e fa'aformulations. 'Oku fakapotopoto 'a e ngaahi naunau 'oku faka'aonga'i ki ha ngaahi me'akai kehekehe, lelei 'a e emulsifiers ki hono teuteu'i ke mahino 'a e nano-emulsions ki hono ngaue 'aki 'i he me'akai, inu, tinctures, 'oku tafataha mo e totongi ki he fakama'a 'o e kili. Ultrasonic homogenisation 'o e lolo/vai 'oku fio 'aki e, 'oku tokoni 'a hono teuteu'i 'o e ki'i me'akai ki he maaka emulsifiers 'i ha lau sekoni pe.

Ta'epau Ph Nano-Emulsions ki he inu, tafataha mo e inu

'Oku emulsifiers ta'epau 'a e Ph emulsifying ko ha kau fakafofonga 'o e me'akai ki he teuteu'i 'o e nano-emulsions ki he inu, me'akai mo e ngaahi me'a 'oku 'i ai hono ngaahi naunau.Ta'epau Ph emulsifier 4514 ko ha emulsifier konga ua ia, 'a ia 'oku faingofua ke mahino nano emulsions. Load ho'o nano emulsion mo bioactive me'a ko'eni hange ko e cannabidiol (FBD), tetrahydrocannabinol (THC), cannabigerol (FBG), vaitamini, antioxidants, polyphenols, curcumin, resveratrol, CoQ10, quercitin pe ngaahi lelei pe nutritionally lelei ngaahi me'a. 'I he taimi 'oku leva me'a encapsulated ai 'i ha emulsion 'oku 'i ai hano nano 'i he vai, hydrophobic (= vai repelling) molecules hoko ko ha tokotaha soluble pea 'e lava pe ke 'ave 'i he fukahi vai 'oku fakava'e 'i he tahi ki he ngaahi selo 'o e fa'ahinga 'o e tangata, 'a ia 'e lava ke peluki ai 'e he ngaahi me'a bioactive 'enau ngaahi ola 'o e fakatupulaki e mo'ui lelei. 'I he taimi 'oku 'ikai ke leva me'a encapsulated ai 'i ha polokalama nano, 'oku fu'u masiva 'aupito 'a e bioavailability mo e absorption 'o e bioactive. Hange ko 'eni, ko e taimi 'oku fakahoko ai 'e he FBD 'a e fakamatala ngutu nano 'oku 'ikai lahi fe'unga, ko e approx pe. 6% FBD, ko e konga lahi 'oku excreted unmetabolized.
Nano-fakalelei'i bioactive 'oku malava ke ma'u ha me'a lahi ange, he ko e absorption mo e metabolisation 'oku mahu'inga 'aupito. 'Oku ola lelei ange 'a e ngaahi naunau ki he Nano-emulsified, 'a e me'akai mo e koloa mo'ui lelei pea 'oku ta'e'aonga mo e ngaahi me'a 'oku si'isi'i hono ngaue'i, pea 'oku lelei ange leva 'a e ngaue ki ai.
Laukonga lahi ange fekau'aki mo e ta'epau Ph emulsifier 4514 ki he inu, 'oku tafataha, 'a e ngaahi me'a fakasosiale mo e ngahi inu kehe!

Kole 'a e fakamatala




Fakatokanga'i ange 'etau Tu'utu'uni totonu fakatautaha.


Ta'epau Ph Nano-Emulsions ki he Edibles

There is an increasing demand from customers for nutritionally enriched edibles such as breads, cakes, muffins, sweets, confectionaries, chocolates, candies, gummies and other food products. To enrich food products effectively with health-promoting substances such as cannabinoids (e.g., CBD, CBD, THC, terpenes etc.), vitamins, antioxidants, polyphenols and other phyto-chemicals, those active ingredients must be made bioavailable. Nano-carriers such as nano-emulsions are the preferred technique to encapsulate bioactive compounds making them thereby water-soluble and increasing their bioavailability.
Laukonga lahi ange fekau'aki mo e ta'epau Ph emulsifier 4514 ki he edibles, lole mo e gummies!

Ngaahi lelei 'o e ta'epau Ph Emulsifiers ki he Nano-Emulsions

  • Maaka e me'atokoni
  • Fotunga mahino
  • 'Olunga bioavailability
  • 'Ahi'ahi lahi, 'ikai ha flavour
  • 'Ikai ha kaunoa 'i he flavour, 'alaha, anga kimu'a
  • Faingofua mo malu ke faka'aonga'i

Ako lahi ange ki he ta'epau Ph emulsifiers ke mahino, soluble e vai nano-FBD formulations!

Ta'epau Ph Nano-Emulsions ki hono tokanga'i 'o e kili mo e Cosmetics

'Oku nano lelei 'a e Ph-emulsifier 1515 ko ha malohi emulsifying ia, 'a ia 'oku fe'unga ke fa'u 'aki ha kili creams, mata moisturizers, sino lotions, fotofota balms, fakalanulanu moisturizers mo concealers, serums, loungutu balms mo e glosses pea mo ha ngaahi naunau kehe. Ko hono emulsifiers ta'epau 'o e Ph 'oku ne fa'u ha nano 'oku lahi ai e lolo 'i he vai, 'a ia 'e lava pe ke fakafonu 'aki ha ngaahi me'a 'oku malohi hange ko e lipids, vaitamini, antioxidants, polyphenols mo ha ngaahi me'a 'aonga kehe. 'I he ta'epau Ph emulsifier 1515 'oku faingofua leva ke ne fa'u ha ngaahi naunau lahi ki hono ngaohi hono kili pea mo ha ngaahi faito'o 'oku 'afa'i. 'Oku fakafaingofua'i 'e he ngaahi ngaue 'a e nano 'a e hu mai 'a e kaingalotu ki he ngaahi selo, 'a ia te nau lava 'o peluki ai honau tu'unga kakato 'o e ngaahi ola lelei.
Laukonga lahi ange fekau'aki mo e pelepelengesi Ph emulsifier 1515 ki he tokanga'i 'o e kili, cosmetics mo e totongi fakatautaha!

Ultrasonic 'e he Emulsification 'ene ta'epau Ph Emulsifiers

Ultrasonicator UP400St ma'a e nano-emulsification 'i he fehokotaki mo e ta'epau Ph nano-emulsifier'Oku homogenisation 'e he ultrasonic 'a e fio ko ia 'a e filosefa Ph emulsifiers 'aki 'a e lolo/vai mixtures ke fa'u ha fale tauhi'anga mo ha nano. 'Oku poupou'i 'e ultrasonic emulsification 'a e encapsulation 'o e ngaahi me'a 'oku malohi hange ko e FBD, THC, vaitamini, polyphenols, antioxidants mo e ngaahi me'a kehe ke fakatupulaki 'i he mo'ui ni, ki he emulsions 'i he vai. 'Oku 'i ai ha potency ma'olunga ange 'i he ngaahi me'a ko ia kuo nano fakatupulaki pea 'oku lava ke ma'u ai 'a e ngaahi me'a 'oku ngaue malohi mei ai, he 'oku tuku mai 'a e ngaahi me'a 'oku ngaue'i 'i ha tu'unga ma'olunga ki he ngaahi selo. 'Oku 'uhinga 'a e metabolisation ma'olunga ange ki ha potency ma'olunga ange 'o ma'u ai ha ngaahi founga longomo'ui.
Ultrasonics 'o e Hielscher’ 'Oku falala'anga e ngaahi processors ngaue 'a e fanga hosi 'i honau ngaue'anga: 'Oku faka'ata 'e he robustness 'o e me'angaue ultrasonic 'a Hielscher, 'a e ngaue mamafa mo e 24/7 ngaahi 'atakai 'oku femo'uekina. Ko e fakamatala fakahangatonu protocolling 'o e ngaahi la'i kaati SD 'oku faka'ata ai 'a e koloa standardisation mo kei lelei 'aupito. 'Ai ke tu'unga ko ho'o ngaahi ki ki hono fa'u 'o ha founga standardised mo sonication Protocol 'o faka'aonga'i 'a e Hielscher ultrasonicators. 'Oku malava heni ke fakahoko 'a e founga ngaue Standadization mo e ngaahi founga ngaohi lelei (GMP).
'Oku 'omi 'e he e tepile 'i lalo ha faka'ilonga ia 'o e tu'unga 'o e ngaue ki he fakafuofua'i 'o e hotau ultrasonicators:

Kulupu (batch) 'o e tohi 'Oku tafe mai 'a e 'ea 'Oku fokotu'u atu 'a e ngaahi me'angaue
mL 'o e 1 ki he 500 10 ki he 200mL/miniti 'e UP100H
mL 'i he 10 ki he 2000 20 ki he 400mL/miniti 'e UP200Ht, UP400St
0.1 ki he 20L 0.2 ke 4L/miniti 'e UIP2000hdT
10 ki he 100L 2 ki he 10L/miniti 'e UIP4000hdT
n.a. 10 ki he 100L/miniti 'e UIP16000
n.a. lalahi fakataha'i 'o e UIP16000

Fetu'utaki mai kiate kimautolu! / Kole kiate kitautolu!

Kole ki ha fakamatala lahi ange

Kataki 'o ngaue 'aki e foomu 'i lalo ke kole ha toe fakamatala ki he ultrasonic processors, faka'aonga'i mo e totongi. Te mau fiefia ke alea'i e founga 'oku mo 'i ai mo ho'omou ngaahi fie ma'u ultrasonic he polokalama!









Kataki 'o fakatokanga'i ange 'etau Tu'utu'uni totonu fakatautaha.




Ngaahi mo'oni'i me'a 'oku mahu'inga ke 'ilo'i

Founga Emulsions mo e Emulsion-based

Emulsion-based delivery systems and particularly nano-emulsion systems are widely used in the cosmetics, pharma, food and beverage industries. Emulsions are colloidal dispersions that consist of two immiscible liquids in which one phase (dispersed phase) is dispersed as small droplets into another phase (continuous phase) in the presence of a surfactant (emulsifying agent).
'I he taimi ko ia 'oku 'ikai ha emulsion (ta'e kau ai ha surfactant), 'e motuhi pea mavahe atu ki hono tu'unga totonu 'i he'ene ngaue, ke faka'aonga'i 'a e ngaahi ivi 'o e emulsifiers mo e tumu'aki (e.g., sonication) kae lava ke teuteu kinetically emulsions.

Fa'ahinga Emulsion: Emulsion 'e lava ke differentiated ki he vai-ki he-tahi (o/w) mo e vai 'i he-lolo (u/o) pea pehe ki he fo'i veesi emulsions (o/w/o/o/o/w) emulsions.

Emulsion honau lalahi: 'Oku toe differentiated ange 'a e Emulsions 'i he lahi 'o e fo'i tulutaa. Fakatatau ki he fo'i tulutaa inisi honau matolu, 'oku ui 'a emulsion ko e macro-, nano, mo e Micro-emulsions.
'Oku Macroemusions ma'u ha droplets lahi pea 'avalisi inisi honau matolu lahi ange ia 'i 200nm. 'Oku turbid pe kaniva 'a honau fotunga.
Nanoemulsions ma'u ha 'avalisi 'o e fo'i tulutaa inisi honau matolu 'o e 20 – 200 NM. 'Oku Nanoemulsions mahino pe translucent.
Microemulsions ha ki'i fo'i tulutaa diameters 'o e 5 – 100 NM, 'o ke ma'u ai ha fotunga mahino. 'Oku thermodynamically 'a e tu'unga lelei ko e tupu mei he hoha'a hono fofonga ultralow 'i he vaha'a 'o e aqueous mo e lolo.

Maaka-Emulsions

Emulsions 'a e maaka 'o e me'atokoni ko e ngaahi konga kotoa pe 'o nanoemulsions (aqueous, lolo mo e emulsifier, kaunga-surfactant), 'oku malu ia ki he lau 'a e tangata pe ' ' 'iloa ko e malu ' (GRAS). 'Oku lahi e fetokanga'aki 'a e emulsions nano-encapsulation, pea kuo 'osi fokotu'u pe ia 'i he 'osi 'a e mo e fie ma'u ke fai ha ngaahi me'a, pea bioactive ha ngaahi me'a mo e ivi.
In nanoemulsion encapsulated active ingredients have an improved stability preventing the coalescence and separation of the droplets. Another very important advantage of nano-emulsions is the superior bioavailability and absorption rate. The nano-sized droplets show improved solubility and stability properties, offer enhanced oral bioavailability and biological efficacy of the encapsulated active substances.