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MultiPhaseCavitator-Insert for Ultrasonic Flow Cell
The MultiPhaseCavitator Insert (InsertMPC48) is designed to improve the ultrasonic processing of liquid/liquid or liquid/gas mixes. 48 very fine cannulas inject liquid or gas into a liquid phase right in the cavitation zone. This creates very small suspended droplets or…
https://www.hielscher.com/multiphasecavitator-insert-for-ultrasonic-flow-cell-reactor.htmHow To Use Hielscher Ultrasonic Tissue Homogenizers
Before purifying or characterizing intracellular macromolecules such as proteins, organelles, enzymes, or active compounds, it is essential to employ an efficient method for tissue lysis and cell disintegration. Ultrasonication is a highly effective technique for cell preparation, quickly releasing intracellular…
https://www.hielscher.com/how-to-use-hielschers-ultrasonic-tissue-homogenizers.htmSample Preparation with the Ultrasonic VialTweeter
Sample preparation before analysis can require various pre-analytical processes such as tissue homogenization, lysis, extraction of proteins, DNA, RNA, organelles and other intracellular substances, dissolving and degassing. The VialTweeter is a unique ultrasonic device that prepares multiple sample tubes simultaneously…
https://www.hielscher.com/sample-preparation-with-the-ultrasonic-vialtweeter.htmBiosynthetic Production of Human Milk Oligosaccharides
The biosynthesis of human milk oligosaccharides (HMOs) via fermentation or enzymatic reactions is a complex, consuming and often low-yielding process. Ultrasonication increases the mass transfer between substrate and cell factories ans stimulates cell growth and metabolism. Thereby, sonication intensifies fermentation…
https://www.hielscher.com/human-milk-oligosaccharides.htmSonochemically Nanostructured Implants Improving Osseointegration
Implants, orthopedic prostheses and dental implants are made mainly from titanium and alloys. Sonication is used to create nanostructured surfaces on metallic implants. Ultrasonic nanostructuring allows to modify metallic surfaces generating uniformly distributed nano-sized patterns on implant surfaces. These nanostructured…
https://www.hielscher.com/sonochemically-nanostructured-implants-improving-osseointegration.htmGenetic Transformation in Plant Cells using Ultrasonics
Sonication-Assisted Agrobacterium-Mediated Transformation (SAAT) is an efficient method to infect plant cells with foreign genes using Agrobacterium as transporter. Ultrasonic cavitation causes sonoporation, which can be described as targeted micro-wounding of plant tissue. Via these ultrasonically creates micro-wounds, DNA and…
https://www.hielscher.com/genetic-transformation-in-plant-cells-using-ultrasonics.htmUltrasonic Lysis for Western Blotting
The western blot is an analytical procedure for the detection of specific proteins in a sample of tissue homogenate or cell extract. To run a Western blot or to measure enzyme activity, many assays require access to the materials (e.g.…
https://www.hielscher.com/ultrasonic-lysis-for-western-blotting.htmUltrasonic Disintegration of Cells
Ultrasonication is an effective means of disintegrating cell structures. Therefore, sonicators are widely used in laboratories to break open cells, extract intracellular molecules, proteins and organelles for research and analysis. On industrial scale, ultrasonic disintegration and lysis is used to…
https://www.hielscher.com/cell_disintegration_01.htmUltrasonic Solutions for Improved Vaccine Production
Sonication is used in various steps of vaccines preparation: for cell lysis, to homogenize cell suspensions, to stimulate cell growth, for encapsulation, for adjuvant protein binding etc. Hielscher sonicators are used in the antigen production, encapsulation and formulation as well…
https://www.hielscher.com/ultrasonic-solutions-for-improved-vaccine-production.htmUltrasonic Lysis of Drosophila Melanogaster Samples
Drosophila melanogaster is widely used in laboratories as model organism. Therefore, pre-analytical preparation steps such as lysis, cell disruption, protein extraction and DNA shearing of Drosophila melanogaster samples must be frequently carried out. Ultrasonic dismembrators are reliable and efficient and…
https://www.hielscher.com/lysis-of-drosophila-melanogaster-samples.htmUltrasonic Preparation of Platelet Rich Serum
Platelet-rich plasma (PRP) is blood plasma that has been enriched with platelets, which is used for medical and estethic treatments. Ultrasonic lysis and conditioning is an very effective method to prepare platelet-rich plasma. Hielscher Ultrasonics offers various ultrasonic systems matching…
https://www.hielscher.com/ultrasonic-preparation-of-platelet-rich-serum.htmSterile Sonication of Falcon Tubes
The VialTweeter VT26dxx is an ultrasonic sample homogenizer designed specifically for Falcon tubes. The VialTweeter VT26dxx sonicates the sample in a Falcon tube indirectly, avoiding the insertion of an ultrasonic probe into the sample. This allows cross-contamination and sample loss…
https://www.hielscher.com/sterile-sonication-of-falcon-tubes.htm